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Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism -; the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

Study assesses the effectiveness of photobiomodulation (PBM) treatment in a mouse model of Alzheimer's disease and finds no significant impact on behavioral performance or neurodegeneration, suggesting the need for further research into PBM's therapeutic potential.

16 Nov 2023

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

A subtype of CD8 T cells, which are classically known to promote immune system responses, may be in fact regulating the immune system by suppressing immune cells causing self-destructive responses leading to autoimmune disorders and organ graft rejection.

15 Nov 2023

Study sheds new light on key cellular processes involved in Parkinson's disease progression

In a study published in Nature Communications, investigators at Beth Israel Deaconess Medical Center (BIDMC) shed new light on key cellular processes involved in the progression of Parkinson's disease (PD).

15 Nov 2023

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model."

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

New research reveals broccoli sprouts may alleviate Crohn's disease symptoms in youth

The impact of broccoli sprouts and its role in resolving Crohn’s disease symptoms.

14 Nov 2023

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Psychedelic compounds such as psilocybin, a substance found in various mushroom species, are garnering more research support as novel treatments for psychiatric disorders, but questions remain concerning who they may help the most.

13 Nov 2023

Changing environment can have long-term, significant effects on the brain

Changes in a person's environment can have long-term, significant effects on the brain, whether it's the inhalation of wildfire smoke or the experience of childhood trauma.

13 Nov 2023

Broccoli sprouts diet protects mice from Crohn's disease, study shows

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD), according to a study conducted in mice.

9 Nov 2023

New study reveals link between autism brain states and early life memory retention

Neuroscientists have discovered a fascinating connection between the retention of early life memories and brain developmental trajectories associated with autism [Wednesday 8th November 2023].

8 Nov 2023

Diabetes breakthrough: Scientists uncover novel route to stimulate beta cell growth

Researchers at Weill Cornell Medicine have uncovered a novel route to stimulate the growth of healthy insulin-producing pancreatic beta cells in a preclinical model of diabetes.

8 Nov 2023

New drug shows exciting promise for the treatment of ALS

In science, a simple but thorough observation can kick-start the most surprising findings. Researchers at the Hollings Cancer Center at the Medical University of South Carolina noticed that mice lacking a protein of interest in cancer research were showing visible signs of abnormal motor functions as they aged, including loss of coordination and strength.

8 Nov 2023

Mouse Model News and Research

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

Study sheds new light on key cellular processes involved in Parkinson's disease progression

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

New research reveals broccoli sprouts may alleviate Crohn's disease symptoms in youth

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Changing environment can have long-term, significant effects on the brain

Broccoli sprouts diet protects mice from Crohn's disease, study shows

New study reveals link between autism brain states and early life memory retention

Diabetes breakthrough: Scientists uncover novel route to stimulate beta cell growth

New drug shows exciting promise for the treatment of ALS

Yabing Chen receives NIH grants to advance vascular disease research

Telomouse model provides a valuable resource for in-depth aging and cancer research

Overcoming T-cell exhaustion: A new hope for CAR-T cell therapy

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Citrus compounds show zesty promise in type 2 diabetes management

Gut bacteria promote social behavior and wound healing through oxytocin signaling

LHPP gene identified as a potential target for treatment-resistant depression

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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