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Abnormally low level of SMN protein linked to movement problems in spinal muscular atrophy

An abnormally low level of a protein in certain nerve cells is linked to movement problems that characterize the deadly childhood disorder spinal muscular atrophy, new research in animals suggests.

12 Apr 2012

Johns Hopkins cardiologists support use of statins for primary prevention of heart attack

Writing the first commentary for a new feature in the Journal of the American Medical Association (JAMA), called Viewpoint, Johns Hopkins cardiologists make the case for why a 55-year-old man with a 10 percent estimated risk of heart attack over the next 10 years should be offered statin medication. They were invited to debate a professor who argues against prescribing statins for "primary" prevention—for those who have not had a cardiovascular event, such as a heart attack—even though they may be considered at "intermediate" risk because of elevated cholesterol or other factors.

12 Apr 2012

Study: Stem cells from pelvic bone marrow may help hearts beat stronger

Stem cells from the pelvic bone may help hearts beat stronger. Doctors and other clinicians at the Orlando Health Heart Institute are researching the use of stem cells from pelvic bone marrow to restore tissue and improve heart function after muscle damage from heart attacks.

12 Apr 2012

Biogen Idec launches FAMPYRA in Canada

Today, Biogen Idec Canada announces that FAMPYRA (fampridine sustained release tablets or fampridine SR) is now available for prescription for patients living with multiple sclerosis (MS) in Canada.

12 Apr 2012

Mayo Clinic to offer novel device for patients with GERD

Mayo Clinic in Florida will be one of the first health care institutions in the United States to offer a newly approved device to treat gastroesophageal reflux disease (GERD). The condition, also known as acid reflux disease, can lead to serious health problems.

12 Apr 2012

Takeda enters definitive agreement to acquire URL Pharma

Takeda Pharmaceutical Company Limited and URL Pharma Inc. jointly announced that Takeda's wholly-owned subsidiary, Takeda America Holdings, Inc. and URL Pharma have entered into a definitive agreement to acquire URL Pharma – a privately-held pharmaceutical company headquartered in Philadelphia, Pennsylvania, for an upfront payment of $800 million and future performance-based contingent earn out payments.

12 Apr 2012

Pelvic floor muscle training effective for adult women with urinary incontinence

A type of exercise called pelvic floor muscle training is effective for treating adult women with urinary incontinence (the involuntary loss of urine) without risk of side effects, according to a new report from the U.S. Department of Health and Human Services' (HHS) Agency for Healthcare Research and Quality (AHRQ). The report also found that drug-based treatments can be effective, but the degree of benefit is low and side effects are common.

11 Apr 2012

NYU Langone announces opening of Center for Musculoskeletal Care

NYU Langone Medical Center ushered in the next generation of orthopaedic, rheumatologic and rehabilitative care with the opening of the Center for Musculoskeletal Care (CMC) at 333 East 38th Street in Manhattan last week.

11 Apr 2012

Neutra to initiate new round of clinical trials on Pure Plus Weight Loss formula

Neutra Corp., an emerging provider of nutraceutical products, announced today that it's gearing up to start a new round of clinical trials on the company's Pure Plus Weight Loss formula, which now includes new ingredients raspberry ketone and African mango.

10 Apr 2012

UCSD surgeon implants new INX device in a 29-year old patient with GERD

On Monday, April 9, Santiago Horgan, MD, chief of minimally invasive surgery at UC San Diego Health System implanted the new FDA-approved LINX device in a 29-year old patient suffering from gastroesophageal reflux disease (GERD), a chronic digestive disease that can lead to severe inflammation, stricture, Barrett's esophagus and esophageal cancer.

10 Apr 2012

Higher blood glucose levels may improve survival rates for heart failure patients with diabetes

Lowering glucose levels for people with diabetes is normally critical to improving health outcomes. But for those with heart failure, that might not always be the case, say UCLA researchers.

10 Apr 2012

KLF15 gene governs the body's ability to burn fat during exercise

While exercise is accepted universally as the most beneficial prescription physicians can write for patients, little is known about the molecular mechanisms that generate its widespread health benefits. Researchers from Case Western Reserve School of Medicine have shed light on this mystery by discovering that a genetic factor, Kruppel-like Factor 15 (KLF15), governs the body's ability to burn fat during exercise.

10 Apr 2012

Researchers question wisdom of blocking DP1 in patients prone to cardiovascular disease

Niacin, or vitamin B3, is the one approved drug that elevates "good" cholesterol (high density lipoprotein, HDL) while depressing "bad" cholesterol (low density lipoprotein , LDL), and has thereby attracted much attention from patients and physicians. Niacin keeps fat from breaking down, and so obstructs the availability of LDL building blocks.

9 Apr 2012

FDA grants IDE approval for Arteriocyte's Magellan MAR01 Phase I Compartment Syndrome clinical trial

Arteriocyte, a leading biotechnology company with offices in Cleveland, Ohio and Hopkinton, Massachusetts announced today approval from the Food and Drug Administration (FDA) to initiate a Phase I clinical trial using its Magellan MAR01 technology in the treatment of Compartment Syndrome.

7 Apr 2012

Hot topics in the Journal of Bone and Joint Surgery

Airport security screening has increased substantially during the past decade, while joint replacement procedures also continue to rise. According to the American Academy of Orthopaedic Surgeons (AAOS), in 2009, nearly 300,000 total hip replacements (THR) were performed in the United States.

6 Apr 2012

Tonix completes TNX-102 pharmacokinetic study on fibromyalgia syndrome

Tonix Pharmaceuticals Holding Corp., a specialty pharmaceutical company developing therapies for challenging disorders of the central nervous system completed a pharmacokinetic (PK) study of the first formulation of its lead drug, TNX-102, for the treatment of fibromyalgia syndrome.

6 Apr 2012

Astellas' mirabegron for OAB receives FDA advisory committee approval

Astellas Pharma US, Inc., a U.S. subsidiary of Tokyo-based Astellas Pharma Inc., announced today that the Reproductive Health Drugs Advisory Committee of the U.S. Food and Drug Administration voted that the overall risk/benefit assessment supports approval of mirabegron for the treatment of overactive bladder.

6 Apr 2012

Spectrum’s apaziquone Phase 3 trials on bladder cancer do not meet primary endpoint

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced that the two double blind, randomized, placebo controlled, Phase 3 clinical trials for apaziquone did not meet their primary endpoint of a statistically significant difference in the rate of tumor recurrence at 2 years between the two arms.

6 Apr 2012

Financial incentives for purchasing a healthier food option

The aging baby boomers and subsequent generations will be looking to the food industry to provide products that can help them live longer, healthier and more active lives than previous generations, according to research presented at the Institute of Food Technologists' Wellness 12 meeting.

5 Apr 2012

Vaccination most promising against asthma

Asthma is a chronic inflammatory and respiratory disease caused by an abnormal reactivity to allergens in the environment. Of the several avenues of exploration that are currently being developed, vaccination appears to be the most promising approach.

5 Apr 2012

Muscle News and Research

Abnormally low level of SMN protein linked to movement problems in spinal muscular atrophy

Johns Hopkins cardiologists support use of statins for primary prevention of heart attack

Study: Stem cells from pelvic bone marrow may help hearts beat stronger

Biogen Idec launches FAMPYRA in Canada

Mayo Clinic to offer novel device for patients with GERD

Takeda enters definitive agreement to acquire URL Pharma

Pelvic floor muscle training effective for adult women with urinary incontinence

NYU Langone announces opening of Center for Musculoskeletal Care

Neutra to initiate new round of clinical trials on Pure Plus Weight Loss formula

UCSD surgeon implants new INX device in a 29-year old patient with GERD

Higher blood glucose levels may improve survival rates for heart failure patients with diabetes

KLF15 gene governs the body's ability to burn fat during exercise

Researchers question wisdom of blocking DP1 in patients prone to cardiovascular disease

FDA grants IDE approval for Arteriocyte's Magellan MAR01 Phase I Compartment Syndrome clinical trial

Hot topics in the Journal of Bone and Joint Surgery

Tonix completes TNX-102 pharmacokinetic study on fibromyalgia syndrome

Astellas' mirabegron for OAB receives FDA advisory committee approval

Spectrum’s apaziquone Phase 3 trials on bladder cancer do not meet primary endpoint

Financial incentives for purchasing a healthier food option

Vaccination most promising against asthma

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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