Muscle News and Research

RSS

Apnex HGNS System shows promising results in people suffering from OSA

Apnex Medical announced today that preliminary data from a first-in-man clinical study showed significant improvements in sleep for people suffering from obstructive sleep apnea. The Apnex HGNS™ System, developed by the St. Paul-based company, is a device designed to treat OSA, which is a serious life-threatening illness characterized by fragmented sleep and excessive day-time sleepiness.

18 May 2010

Celldex Therapeutics commences screening in CDX-1307 Phase 2 study for bladder cancer

Celldex Therapeutics, Inc. today announced that the first patient has been screened in a randomized Phase 2 study of the Company's novel, first-in-class antibody-based vaccine candidate from its Precision Targeted Immunotherapy (PTI) platform. This study will evaluate the CDX-1307 regimen in both neoadjuvant and adjuvant settings in patients with newly diagnosed muscle-invasive bladder cancers that express hCG-beta.

17 May 2010

Tufts University's School of Arts and Sciences receives $9.5M grant to create research space

Tufts University's School of Arts and Sciences has received a $9.5 million grant to create research space that will house a Collaborative Cluster in Genome Structure and Developmental Patterning in Health and Disease.

17 May 2010

Obese patients with COPD improve following pulmonary rehabilitation program: Research

Obese patients with chronic obstructive pulmonary disease stand to gain as much from pulmonary rehabilitation as their slimmer counterparts, even though as a group they have a lower exercise capacity, according to new research from the University Hospitals of Leicester in the UK.

17 May 2010

Female sex hormones may work with estrogen in reducing airway constriction: Research

Female sex hormones may work with beta-agonists in reducing airway constriction, according to new bench research from the Mayo Clinic.

17 May 2010

Blood flow restriction combined with resistance exercise can increase muscle-mass in older men

For years, researchers have known that resistance exercise training -such as weightlifting, in which muscles work against gravity or another force - can be one of the most effective ways to fight the debilitating muscle loss caused by aging.

15 May 2010

Duchenne Muscular Dystrophy Awareness Week declared to honor work of PPMD

The Pennsylvania House of Representatives has passed a resolution declaring the week of May 24, 2010 as "Duchenne Muscular Dystrophy Awareness Week" to help honor the work of Parent Project Muscular Dystrophy, the largest non-profit organization in the United States focused on finding a cure for Duchenne muscular dystrophy.

15 May 2010

Fat tissue different in men and women

The age-old question of why men store fat in their bellies and women store it in their hips may have finally been answered: Genetically speaking, the fat tissue is almost completely different.

15 May 2010

Small anti-abortion advocacy group flexes muscle in midterm elections

The Washington Post reports on the increasingly important role of a small antiabortion advocacy group, the Susan B. Anthony List, which is targeting Senate Majority Leader Harry Reid in his bid for re-election.

15 May 2010

Male physical competition central in winning mates among human ancestors: Penn State

Male physical competition, not attraction, was central in winning mates among human ancestors, according to a Penn State anthropologist.

14 May 2010

Rensselaer professor selected to receive NSF CAREER Award

David T. Corr, assistant professor in the Department of Biomedical Engineering at Rensselaer Polytechnic Institute, has won a Faculty Early Career Development Award from the National Science Foundation.

14 May 2010

GRNCM1 do not cause cardiac arrhythmias after transplantation: Preclinical study

Geron Corporation today reported positive preclinical study data showing that GRNCM1, Geron's cardiomyocyte product derived from human embryonic stem cells, does not cause cardiac arrhythmias after transplantation into a model of chronic heart damage designed to test this potential safety concern.

14 May 2010

Mild-mannered organelles can detect virus invasion signals: Researchers

Within cells, an ancient antiviral duo can deliver a one-two knockout to thwart invading viruses, report researchers who have just unmasked the cellular sidekick that throws the first punch. The findings mean scientists must rethink the design of antiviral immunity and how the body fends off viruses of all types, including influenza and HIV.

14 May 2010

Canadian tourist bitten by a Katipo spider in New Zealand

A Canadian tourist suffered a serious heart inflammation called myocarditis after he was bitten by a poisonous spider when he went swimming nude in New Zealand.

13 May 2010

Repligen files IND for Phase 1 study of RG2833 selective HDAC-3 inhibitor for Friedreich's ataxia

Repligen Corporation announced today that it has filed an Investigational New Drug Application (IND) with the Food and Drug Administration (FDA) for a Phase 1 study of RG2833, a selective histone deacetylase 3 (HDAC-3) inhibitor. This is a double-blind, single ascending dose, Phase 1 study in healthy volunteers to evaluate the pharmacokinetic and safety profile of RG2833 in up to 40 subjects.

13 May 2010

25% of adults quit their overactive bladder medication: Study

Study of 5,392 adults found that a quarter had quit their overactive bladder medication, with nine out of ten saying it didn't work as expected or they couldn't tolerate it. A follow-up study found that being a current smoker raised the risk of quitting by 80%, having an enlarged prostate by 74% and believing that bladder medication caused side effects by 111%.

13 May 2010

Trubion Pharmaceuticals to present promising data from Phase 1 studies of SBI-087, SBI-087

Trubion Pharmaceuticals, Inc. today announced the acceptance of two Phase 1 data presentations on SBI-087 (PF-05230895) at the 2010 annual congress of the European League Against Rheumatism (EULAR) in Rome, Italy. Presentations will include promising data from a Phase 1 study of SBI-087 for the treatment of rheumatoid arthritis (RA) and a Phase 1 study of SBI-087 for the treatment of systemic lupus erythematosus (SLE). Copies of both abstracts are available at http://www.eular.org. SBI-087 is Trubion's next-generation CD20-directed small modular immunopharmaceutical (SMIP™) product candidate and is being developed in collaboration with Pfizer.

13 May 2010

Pfizer to acquire terguride from Ergonex Pharma GmbH for treatment of PAH

Pfizer Inc. and Ergonex Pharma GmbH announced today that they have entered into an agreement under which Pfizer will acquire terguride, which is in development as a potential treatment for Pulmonary Arterial Hypertension.

13 May 2010

Bioniche third-quarter consolidated revenues increase 111% to $15.6 million

Bioniche Life Sciences Inc., a research-based, technology-driven Canadian biopharmaceutical company, today announced financial results for its Fiscal 2010 third quarter, ended March 31, 2010.

12 May 2010

Optivia Biotechnology launches OptiDDI Suite for assessing transporter-related DDIs

Optivia Biotechnology Inc., a leading provider of in vitro transporter assay services, today announced the launch of the OptiDDITM Suite, a novel assay panel that assesses the most clinically significant transporter-related drug-drug interactions (DDIs), as identified by the International Transporter Consortium (ITC) in its report "Membrane Transporters in Drug Development" (Nature Reviews-Drug Discovery, March 2010).

12 May 2010

Muscle News and Research

Apnex HGNS System shows promising results in people suffering from OSA

Celldex Therapeutics commences screening in CDX-1307 Phase 2 study for bladder cancer

Tufts University's School of Arts and Sciences receives $9.5M grant to create research space

Obese patients with COPD improve following pulmonary rehabilitation program: Research

Female sex hormones may work with estrogen in reducing airway constriction: Research

Blood flow restriction combined with resistance exercise can increase muscle-mass in older men

Duchenne Muscular Dystrophy Awareness Week declared to honor work of PPMD

Fat tissue different in men and women

Small anti-abortion advocacy group flexes muscle in midterm elections

Male physical competition central in winning mates among human ancestors: Penn State

Rensselaer professor selected to receive NSF CAREER Award

GRNCM1 do not cause cardiac arrhythmias after transplantation: Preclinical study

Mild-mannered organelles can detect virus invasion signals: Researchers

Canadian tourist bitten by a Katipo spider in New Zealand

Repligen files IND for Phase 1 study of RG2833 selective HDAC-3 inhibitor for Friedreich's ataxia

25% of adults quit their overactive bladder medication: Study

Trubion Pharmaceuticals to present promising data from Phase 1 studies of SBI-087, SBI-087

Pfizer to acquire terguride from Ergonex Pharma GmbH for treatment of PAH

Bioniche third-quarter consolidated revenues increase 111% to $15.6 million

Optivia Biotechnology launches OptiDDI Suite for assessing transporter-related DDIs

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News