Muscle News and Research

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Etanercept and chemo might reduce fatigue in cancer patients

Researchers here have found evidence that combining a drug typically used to treat rheumatoid arthritis with chemotherapy might help reduce fatigue and muscle wasting that often afflicts cancer patients.

3 May 2006

Epstein-Barr virus may trigger multiple sclerosis

Researchers have found that patients with multiple sclerosis (MS) carry a population of immune cells that overreact to Epstein-Barr virus.

3 May 2006

Early myocardial enhancement defects (dark spots) on multidetector CT are valuable predictors of myocardial viability

...in patients who have suffered a heart attack, reported doctors from the departments of cardiology and radiology at Rambam Medical Center in Haifa, Israel.

3 May 2006

New drug to treat rare Pompe disease gets FDA approval

The Food and Drug Administration in the U.S. has given approval for the first drug to treat a rare, debilitating muscle disease that can kill infants within a year.

1 May 2006

HCM detection rates doubled when genetic testing and imaging information are combined

Currently that genetic test correctly detects HCM only 40 percent of the time. But coupled with imaging information, the detection power of the test nearly doubles, to 79 percent, says Steve Ommen, M.D., director of Mayo's HCM Clinic and co-lead investigator of the Mayo Clinic research team.

28 Apr 2006

Transplanted stem cells hoped to be able to regenerate damaged heart muscle in first heart attack victims

Rush cardiologists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue.

28 Apr 2006

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Researchers believe they have found a way to change the action of 60 percent of currently available medications, in some cases making them many times more effective, according to an article published in the April 21 edition of the journal Science. The discovery has the potential to improve treatments for diseases including heart disease, cancer, diabetes, depression and arthritis. The study describes a new way to manipulate perhaps the most important signaling mechanism in human cells: G-protein coupled receptors (GPCRs).

28 Apr 2006

Studies indicate stem cells are flexible enough to become any cell in the body

Two studies in the April 21, 2006 Cell report new details of the "genetic program" that affords embryonic stem cells the flexibility to give rise to any cell type in the body. Both groups identified mechanisms by which the embryonic stem cells of mice or humans keep from going down any one particular developmental path--that of muscle or nervous tissue, for example--while remaining "poised for activation."

26 Apr 2006

Studies indicate stem cells are flexible enough to become any cell in the body

26 Apr 2006

Genetic clue found to Chronic Fatigue Syndrome

According to researchers from the Centers for Disease Control and Prevention (CDC), in the United States, there may well be a genetic reason why some people develop Chronic Fatigue Syndrome (CFS).

24 Apr 2006

Research into toxins points to development of better medicines

Researchers have combined magnetic resonance spectroscopy with special protein synthesis procedures to uncover how potassium channels and toxins combine and change in structure. This work could make it possible to develop medications for high blood pressure and many other diseases connected to potassium channel failure .

23 Apr 2006

Protein discovery opens up new therapeutic possibilities for epilepsy and neurodegenerative diseases

UC Irvine researchers have found that a protein best known for building connections between nerve cells and muscle also plays a role in controlling brain cell activity.

23 Apr 2006

Australian scientists tackle deadly Q fever

Scientists at James Cook University have taken the lead in developing a new vaccine against a highly infectious cattleyard disease caused by a bacteria which has the potential to be developed as a bioterrorist weapon.

20 Apr 2006

Corticosteroids do not improve survival in patients with late-stage acute respiratory distress syndrome

The study is the first multi-center randomized clinical trial to evaluate the effects of moderate doses of steroids in ARDS patients when treatment is started 7 days or more after the onset of the condition.

20 Apr 2006

New methods for revealing nerve-muscle activity in live animals

Picking up a pencil, running a marathon, even the simple act of breathing - every time we move a muscle we depend on a series of finely-tuned interactions at the junction of nerve fiber and muscle cell.

20 Apr 2006

Muscles burn lactic acid as well as carbos

In the lore of marathoners and extreme athletes, lactic acid is poison, a waste product that builds up in the muscles and leads to muscle fatigue, reduced performance and pain.

20 Apr 2006

Forearm support reduces pain linked to computer use

Providing forearm support is an effective way to prevent musculoskeletal disorders of the upper body and helps reduce upper body pain associated with computer work, according to a study reported in the April 18 issue of the British Journal of Occupational and Environmental Medicine.

20 Apr 2006