Muscle Wasting News and Research

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Myostatin inhibitors may make injuries more likely

Block the action of a protein that normally regulates muscle mass, and watch your muscles grow.

23 Jan 2008

Stem cell therapy restores muscle function in mice with muscular dystrophy

Scientists in Texas have been able to restore muscle function in mice with muscular dystrophy by using embryonic stem cells.

21 Jan 2008

New insight into factors that drive muscle-building stem cells

A report in the January issue of Cell Metabolism, a publication of Cell Press, provides new evidence explaining how stem cells known as satellite cells contribute to building muscles up in response to exercise.

9 Jan 2008

Discovery of molecular signal that helps muscle regenerate and protects it from atrophy

It does not take much to injure a muscle. Sometimes one sudden, inconsiderate movement does the job.

20 Dec 2007

Reprogrammed human adult stem cells rescue diseased muscle in mice

Scientists report that adult stem cells isolated from humans with muscular dystrophy can be genetically corrected and used to induce functional improvement when transplanted into a mouse model of the disease.

13 Dec 2007

Study to look at effect of exercise and nutrition on muscle in old age

Experts at The University of Nottingham are looking to recruit men of two specific age groups to help understand the effect of exercise and nutrition on muscle in old age.

29 Nov 2007

Discovery of gene responsible for statin-induced muscle pain

Statins, the popular class of drugs used to lower cholesterol, are among the most commonly prescribed medications in developed countries.

27 Nov 2007

Researchers identify compound that eliminates myotonia - a symptom of muscular dystrophy

Researchers at the University of Rochester Medical Center (URMC) have identified a compound that eliminates myotonia - a symptom of muscular dystrophy - in mice. The research was published online in the Journal of Clinical Investigation.

16 Nov 2007

Male contraception

For decades, pundits have predicted new contraceptives for men within the next 5 to 10 years.

29 Sep 2007

Call for more genetic research in the sport and exercise sciences

Genetic research into athletic ability should be encouraged for its potential benefits in both sport and public health, a leading group of scientists meeting at the University of Bath said today.

13 Sep 2007

NASA and NIH to use International Space Station to answer questions about health and diseases

A Sept. 12 signing of a memorandum of understanding marked a key milestone for NASA and the National Institutes of Health in their long partnership to advance scientific discovery.

13 Sep 2007

Novel mutation associated with muscle identified

The study demonstrates that muscle weakness experienced by persons with a regulatory protein tropomyosin mutation is directly related to a mechanism by which the mutant tropomyosin modulates contractile speed and force-generation capacity.

17 Jun 2007

Existence of muscle-building stem cells points to regenerative therapies for muscular disease

A new report in the June 1 issue of the journal Cell, a publication of Cell Press, confirms the existence of some apparently uncommitted stem cells amongst cells responsible for generating the bulging biceps of body builders and the rippling abs of fitness buffs.

1 Jun 2007

Scientists discover pathway that promotes muscle cell survival in mice

Scientists at the Salk Institute for Biological Studies have identified an enzyme that pumps up a cell's ability to maintain healthy muscle and restores normal muscle function in genetically engineered mice with weak muscles.

30 Apr 2007

UNC-45 protein critical to proper formation of muscles

Proper formation of the proteins that power heart and skeletal muscle seems to rely on a precise concentration of a "chaperone" protein known as UNC-45, according to a new study.

24 Apr 2007

New drug offers hope to muscular dystrophy and cystic fibrosis sufferers

Scientists in the United States say an experimental drug may be able to compensate for the genetic error responsible for some cases of Duchenne Muscular Dystrophy (DMD) and cystic fibrosis.

23 Apr 2007

Weight-lifting exercises during dialysis improves muscle mass, strength, quality of life

Performing high-intensity weight-lifting exercise during dialysis sessions brings meaningful improvements in muscle mass, strength, quality of life, and other important health outcomes in patients with end-stage renal disease (ESRD), reports a study in the May Journal of the American Society of Nephrology.

5 Apr 2007