Musculoskeletal News and Research

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FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

The U.S. Food and Drug Administration today expanded the approved use of Imbruvica (ibrutinib) to treat patients with chronic lymphocytic leukemia (CLL) who carry a deletion in chromosome 17 (17p deletion), which is associated with poor responses to standard treatment for CLL. Imbruvica received a breakthrough therapy designation for this use.

29 Jul 2014

EMA CHMP adopts positive opinion for Janssen’s IMBRUVICA to treat CLL and MCL

Janssen-Cilag International NV announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorisation for IMBRUVICA (ibrutinib) in the European Union.

29 Jul 2014

Genetics involved with menarche may hold keys to preventing diabetes or osteoporosis in later life

A novel study shows that the age girls reach puberty is influenced by 'imprinted genes'-a subset of genes whose activity differs depending on which parent contributes the gene.

26 Jul 2014

EMA recommends full marketing approval for IMBRUVICA in the European Union

Pharmacyclics, Inc. today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency issued a positive opinion recommending the granting of full marketing approval for IMBRUVICA (ibrutinib) in the European Union.

25 Jul 2014

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis (MS), can actually protect the brain from traumatic brain injury (TBI) and may slow the progression of neurodegenerative diseases, according to Cleveland Clinic research published today in the online journal Nature Communications.

22 Jul 2014

Telecare approach improves chronic musculoskeletal pain management

A collaborative care approach delivered by telephone is effective for managing chronic musculoskeletal pain, show findings from the Stepped Care to Optimize Pain Care Effectiveness study.

21 Jul 2014

Research roundup: ACA lawsuit primer; ACA strategies in 4 states; competitive plans for those eligible for Medicare and Medicaid

In 2012, the U.S. Supreme Court upheld the constitutionality of the ACA, but that did not end attacks against the law. Since the decision in National Federation of Independent Business v. Sebelius, objecting parties have filed more than 100 cases in federal courts nationwide.

21 Jul 2014

Viewpoints: GOP's 'cynical' lawsuit against Obama; debt crisis is not over

There's not much that Republicans like about the 2010 Affordable Care Act, but one thing they particularly dislike is the requirement that employers with 50 or more full-time workers provide comprehensive health insurance.

18 Jul 2014

Once-a-day pill for patients experiencing opioid-induced constipation

Opioids - strong morphine-based painkillers - are widely prescribed to patients experiencing chronic severe pain. While these drugs are very effective for treating and managing pain, they have one particularly bothersome side effect: constipation.

17 Jul 2014

Phase III research shows that new drug improves symptoms related to plaque psoriasis

Randomized, phase III research from the University of Alabama at Birmingham shows that a new drug improves symptoms related to moderate to severe plaque psoriasis, a chronic skin disease of scaling and inflammation.

17 Jul 2014

Investigators identify gene that underlies devastating autoinflammatory condition in children

Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy (SAVI).

17 Jul 2014

$Reducing the risk of fractures in older women$

Reducing the risk of fractures in older women

Reducing the risk of fractures in older women is the aim of a research study at Griffith University.

16 Jul 2014

Telecare intervention leads to improvement in chronic musculoskeletal pain

A telephone-delivered intervention, which included automated symptom monitoring, produced clinically meaningful improvements in chronic musculoskeletal pain compared to usual care, according to a study in the July 16 issue of JAMA.

16 Jul 2014

Acute episodes of low back pain not linked to weather conditions

Australian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pressure, wind direction and precipitation.

10 Jul 2014

Complications from partial knee replacement is very small than total knee replacement

Partial knee replacement surgery is safer than total knee replacement, according to a new study published in The Lancet today (July 8).

8 Jul 2014

Lung cancer patients could benefit from new 'QTA' technique

Lung cancer patients could receive more precise treatment, and their progress could be better tracked, using a new high-tech method of non-invasive medical imaging analysis, according to a study published today by the journal PLOS ONE.

3 Jul 2014

Stryker Corporation to acquire all assets of Small Bone Innovations for $375M

Small Bone Innovations, Inc. (SBi) today announced that Stryker Corporation will acquire substantially all the assets of SBi in an all cash transaction for up to $375 million.

From Stryker 30 Jun 2014

Keele University researchers awarded grant to develop new treatment for musculoskeletal problems

Researchers at Keele University in the UK have been awarded a £1.93 million National Institute of Health Research (NIHR) Programme Grant for a new five year programme of research to develop a new treatment model for people with musculoskeletal problems in primary care, in which treatment will be tailored to patients' risk of persistent pain and disability.

28 Jun 2014

Street football improves fitness, multiple health markers in homeless men

Research carried out by the Copenhagen Centre for Team Sport and Health in Denmark shows that street football (soccer) improves fitness and multiple health markers in homeless men.

26 Jun 2014

CHEO, ONF jointly launch first comprehensive pediatric concussion guidelines

Pediatric emergency medicine researchers at the Children's Hospital of Eastern Ontario together with the Ontario Neurotrauma Foundation today launch the first comprehensive pediatric concussion guidelines.

25 Jun 2014

Musculoskeletal News and Research

FDA approves use of Imbruvica to treat patients with chronic lymphocytic leukemia

EMA CHMP adopts positive opinion for Janssen’s IMBRUVICA to treat CLL and MCL

Genetics involved with menarche may hold keys to preventing diabetes or osteoporosis in later life

EMA recommends full marketing approval for IMBRUVICA in the European Union

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

Telecare approach improves chronic musculoskeletal pain management

Research roundup: ACA lawsuit primer; ACA strategies in 4 states; competitive plans for those eligible for Medicare and Medicaid

Viewpoints: GOP's 'cynical' lawsuit against Obama; debt crisis is not over

Once-a-day pill for patients experiencing opioid-induced constipation

Phase III research shows that new drug improves symptoms related to plaque psoriasis

Investigators identify gene that underlies devastating autoinflammatory condition in children

Reducing the risk of fractures in older women

Telecare intervention leads to improvement in chronic musculoskeletal pain

Acute episodes of low back pain not linked to weather conditions

Complications from partial knee replacement is very small than total knee replacement

Lung cancer patients could benefit from new 'QTA' technique

Stryker Corporation to acquire all assets of Small Bone Innovations for $375M

Keele University researchers awarded grant to develop new treatment for musculoskeletal problems

Street football improves fitness, multiple health markers in homeless men

CHEO, ONF jointly launch first comprehensive pediatric concussion guidelines

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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