Mutation News and Research

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Scientists develop new approach to accelerate evolution of biomolecules in lab

Scientists at Harvard University have harnessed the prowess of fast-replicating bacterial viruses, also known as phages, to accelerate the evolution of biomolecules in the laboratory.

11 Apr 2011

Research on rare cancers

A cancer diagnosis can be a life-changing event. Many questions arise, with one of the first being, "Where should I be treated?" Patients diagnosed with rare cancers may have difficulty finding a physician knowledgeable in treating their type of cancer.

11 Apr 2011

IDSA, U.S. health officials describe ways to respond to global threat of antimicrobial resistance

To coincide with World Health Day on Thursday, the Infectious Diseases Society of America (IDSA) released a policy paper with nine recommendations for how to control the "ever-growing threat of antimicrobial resistance," CIDRAP News reports.

11 Apr 2011

New nonviral method to create cardiac cells

Johns Hopkins scientists have developed a simplified, cheaper, all-purpose method they say can be used by scientists around the globe to more safely turn blood cells into heart cells. The method is virus-free and produces heart cells that beat with nearly 100 percent efficiency, they claim.

11 Apr 2011

Polaris' ADI-PEG 20 exhibits potential against AML, GBM and bladder cancer

Polaris Group announced today that data from preclinical studies suggest ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, may be effective in treating acute myeloid leukemia (AML), glioblastoma multiforme (GBM) and bladder cancer.

8 Apr 2011

Researchers identify new gene that predisposes people to both autism, epilepsy

Researchers from the CHUM Research Centre have identified a new gene that predisposes people to both autism and epilepsy.

8 Apr 2011

New discovery in cancer and gene therapy

DNA's role as the master blueprint of the cell means that even small sequence changes can have catastrophic consequences. For this reason, much of our understanding of cancer development comes from studying how cells copy DNA and repair sequence errors--and how these processes can go wrong.

8 Apr 2011

CFFT, Vertex collaborate to develop new medicines for cystic fibrosis

Vertex Pharmaceuticals Incorporated and Cystic Fibrosis Foundation Therapeutics, Inc. today announced they will collaborate on the continued discovery and development of new medicines known as correctors that aim to treat the underlying cause of cystic fibrosis in people with the most common form of the disease.

8 Apr 2011

Experts to discuss about links between metabolic function and disease at EB2011

Metabolism encompasses the biochemical reactions that sustain life and is usually thought of as two complementary systems: one that breaks down nutrients to generate energy and another that harnesses this energy to produce the building blocks cells need to thrive.

8 Apr 2011

Johns Hopkins scientists identify autism gene linked to severity of social interaction deficits

With the help of two sets of brothers with autism, Johns Hopkins scientists have identified a gene associated with autism that appears to be linked very specifically to the severity of social interaction deficits.

7 Apr 2011

Superbugs and antibiotic resistance

Health experts come together today (Thursday) to warn that a new form of superbug that gives bacteria the power to resist virtually all known antibiotics is spreading quickly, posing a global health disaster. It is called New Delhi metallobeta-lactamase, or NDM-1 for short. This enzyme destroys carbapenems, an important group of antibiotics used for difficult infections in hospitals, and has been found in a wide variety of bacterial types. British researchers last August reported that infections involving NDM-1 had been found in patients in Bangladesh, India, Pakistan and Britain.

6 Apr 2011

Increased risk of virologic failure associated with NNRTI-based regimens in HIV-1 drug resistance mutations

An analysis of data from 10 studies indicates that the presence of low frequency (also called "minority") human immunodeficiency virus type 1 (HIV-1) drug resistance mutations, particularly those involving nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, are significantly associated with an increased risk of first-line antiretroviral treatment failure, according to an article in the April 6 issue of JAMA.

6 Apr 2011

Researchers identify genetic anomaly that may drive rare subset of prostate cancers

Researchers at the University of Michigan Comprehensive Cancer Center have identified a genetic anomaly that may drive the aggressive spread of a rare subset of prostate cancers.

5 Apr 2011

Synta presents ganetespib and elesclomol study data in cancer at AACR meeting

Synta Pharmaceuticals Corp. today presented five posters at the American Association for Cancer Research 102nd Annual Meeting. Three posters reported results from studies of ganetespib, and two posters reported results from studies of elesclomol, a small-molecule mitochondria metabolism inhibitor.

5 Apr 2011

American Cancer Society awards 85 institutions with $49,213,000 for new research, training

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has awarded 132 national research and training grants totaling $49,213,000 to 85 institutions nationwide in the second of two grants cycles for 2011.

5 Apr 2011

UC researchers sequence individual glioblastoma genomes and track abnormalities through the bloodstream

Medical scientists know this about glioblastoma multiforme: the malignant brain tumor is aggressive, it is elusive, and it appears in different permutations.

5 Apr 2011

Curis presents vismodegib Phase II data in basal cell nevus syndrome at AACR meeting

Curis, Inc., a drug development company seeking to develop next generation targeted small molecule drug candidates for cancer treatment, today announced the presentation of interim Phase II clinical data on Hedgehog pathway inhibitor vismodegib in patients with basal cell nevus syndrome, which is also commonly referred to as Gorlin syndrome.

5 Apr 2011

Mutation News and Research

Scientists develop new approach to accelerate evolution of biomolecules in lab

Research on rare cancers

IDSA, U.S. health officials describe ways to respond to global threat of antimicrobial resistance

New nonviral method to create cardiac cells

Polaris' ADI-PEG 20 exhibits potential against AML, GBM and bladder cancer

Researchers identify new gene that predisposes people to both autism, epilepsy

New discovery in cancer and gene therapy

CFFT, Vertex collaborate to develop new medicines for cystic fibrosis

Experts to discuss about links between metabolic function and disease at EB2011

Johns Hopkins scientists identify autism gene linked to severity of social interaction deficits

Superbugs and antibiotic resistance

Increased risk of virologic failure associated with NNRTI-based regimens in HIV-1 drug resistance mutations

Researchers identify genetic anomaly that may drive rare subset of prostate cancers

Synta presents ganetespib and elesclomol study data in cancer at AACR meeting

American Cancer Society awards 85 institutions with $49,213,000 for new research, training

UC researchers sequence individual glioblastoma genomes and track abnormalities through the bloodstream

Curis presents vismodegib Phase II data in basal cell nevus syndrome at AACR meeting

AACR President-elect to host press conference on cancer risk factors and genetics

Known cancer-linked gene involved in subset of advanced prostate tumors

Women with ovarian cancer having BRCA2 gene mutations are more likely to survive

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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