Mutation News and Research

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Another case of bird flu appears in Laos

World Health Organization (WHO) officials say it is likely 42-year-old woman who died in Laos had bird flu.

4 Mar 2007

Bird flu vaccine offers limited protection but 'better than nothing'

Despite evidence it will not protect most people, a panel of health advisers have recommended that the Food and Drug Administration (FDA) in the United States approve the first vaccine against bird flu.

28 Feb 2007

First 3-D structure from key influenza protein revealed

In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently H5N1, another highly infectious avian strain has caused outbreaks of bird flu around the world.

27 Feb 2007

Genetically caused deafness may be reversible by compensating for a missing protein

Emory University researchers have found that in mice, increasing the amount of the protein connexin26 in the ear's cochlea compensates for an absence of another protein, connexin30.

26 Feb 2007

Irregular heartbeat linked to genetic mutation

Every day for 10 years, a seemingly heart-healthy 53-year-old woman experienced rapid and irregular heartbeats. She had no personal or family history of hypertension or hyperthyroidism. She did not suffer from myocardial or coronary artery disease, or any abnormalities of the heart as best doctors and medical science could determine.

25 Feb 2007

microRNA directly regulates a gene implicated in human cancers

MicroRNAs are tiny snippets of RNA that can repress activity of a gene by targeting the gene's messenger RNA (which copies DNA information and starts the process of protein production).

22 Feb 2007

Entire genetic blueprints of more than 2,000 human and avian influenza viruses completed and made public

The Influenza Genome Sequencing Project, funded by the National Institute of Allergy and Infectious Diseases (NIAID), announced today that it has achieved a major milestone.

21 Feb 2007

More Moscow suburbs affected by bird flu

Russian officials say two more localities near Moscow have reported what appears to be the highly pathogenic H5N1 strain of bird flu.

21 Feb 2007

New test identifies suitable lymphoma patients likely to respond to new therapy

Researchers at the Albert Einstein College of Medicine of Yeshiva University have discovered a genetic signature identifying cases of lymphoma that are uniquely susceptible to a newly developed molecular targeted therapy. As a result, physicians organizing clinical trials of the new therapy will be able to enroll patients who'll be most likely to benefit from it.

20 Feb 2007

Cancer cells 100 times more likely to genetically mutate

When cells become cancerous, they also become 100 times more likely to genetically mutate than regular cells, researchers have found. The findings may explain why cells in a tumor have so many genetic mutations, but could also be bad news for cancer treatments that target a particular gene controlling cancer malignancy.

20 Feb 2007

Transmission of drug-resistant tuberculosis among treated patients in Shanghai

A newly released study suggests that the majority of cases of drug-resistant tuberculosis (TB) among patients undergoing treatment for the disease may be due to new infections, not acquired resistance.

20 Feb 2007

Genetic mutations make people susceptible to schizophrenia

Gene mutations governing a key brain enzyme make people susceptible to schizophrenia and may be targeted in future treatments for the psychiatric illness, according to MIT and Japanese researchers.

20 Feb 2007

Popular Russian pet market the source of latest bird flu outbreak

Russian veterinary officials have closed down a popular pet market in Moscow after the recent outbreaks of the deadly bird flu were all traced back to the market.

19 Feb 2007

Scientists discover vulnerable area on HIV that could lead to development of HIV/AIDS vaccine

Scientists on Wednesday announced they had identified a vulnerable area on HIV that might be susceptible to antibodies and could prevent the virus from infecting human cells, Reuters Health reports. The findings are published in the Feb. 15 issue of the journal Nature.

19 Feb 2007

Fourth outbreak of bird flu threatens Moscow

According to Russian authorities a fourth outbreak of the H5N1 bird-flu virus has been discovered in suburban Moscow.

18 Feb 2007

Researchers determine a critical factor in workings of proteins

Scientists know that a better understanding of how proteins bond could lead to more effective treatments for genetic disorders and other life-threatening conditions.

18 Feb 2007

New targets in cancer mutation puzzle

University of Rochester scientists, while investigating the two most frequent types of mutations in cancer, discovered a possible new route to treatment that would take advantage of the mutations instead of trying to repair them.

18 Feb 2007

Bird flu - latest case in Egypt

The World Health Organization (WHO) has confirmed that an Egyptian woman has tested positive for the H5N1 bird flu virus.

18 Feb 2007

Study shows PanK2 enzyme within mitochondria is triggered by the first step in fatty acid breakdown

Just as homes have smoke detectors, cells have an enzyme that responds to a buildup of fatty acids by triggering the production of a key molecule in the biochemical pathway that breaks them down, according to investigators at St. Jude Children's Research Hospital. This provides the cell energy while reducing the chance that excess fatty acids will accumulate.

15 Feb 2007

Survey finds perceived risk of recurrence is low in African American breast cancer survivors

A unique survey of African American breast cancer survivors at heightened risk for hereditary breast cancer has found the majority do not believe they have an increased chance of developing the cancer again.

15 Feb 2007