Mycology News and Research

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New understanding of ubiquitylation

It turns out there's more than one way to skin a gene. New research from Rockefeller University suggests that two closely related DNA unpackaging mechanisms may not work the way scientists thought.

10 May 2007

New understanding of infectious prion

Researchers have known for decades that certain neurodegenerative diseases, such as mad cow disease or its human equivalent, Cruetzfeldt-Jakob disease, result from a kind of infectious protein called a prion.

10 May 2007

Alzheimer's disease, Parkinson's disease, type 2 diabetes similar at the molecular level

Alzheimer's disease, Parkinson's disease, type 2 diabetes, the human version of mad cow disease (Creutzfeldt-Jakob disease), and other degenerative diseases are more closely related at the molecular level than many scientists realized, an international team of researchers, including an ESRF researcher, report in the journal Nature.

8 May 2007

New compounds promising candidates for neurodegenerative disease drug development

Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.

8 May 2007

New vitamin extends lifespan in yeast cells

Imagine taking a vitamin for longevity! Not yet, but a Dartmouth discovery that a cousin of niacin prolongs lifespan in yeast brings the tantalizing possibility a step closer.

4 May 2007

Scientists discover molecular mechanism that keeps HSV-1 activation restricted to a single gene for months or even years

By adulthood, most people have suffered at least one bout of painful cold sores brought on by the Herpes simplex virus 1, also known as HSV-1.

4 May 2007

To live longer - eat less!

Scientists have known for a long time that animals fed diets which border on starvation live longer, but they are now saying that a particular gene is linked to calorie restriction.

3 May 2007

Methods for marking molecules to identify gene alterations and metabolic shifts

Physical alterations of DNA in chromosomes can cause serious diseases such as Down syndrome, Prader-Willi syndrome, or cancer.

2 May 2007

Important step towards a spatially and temporally quantifiable model of the cell

Cell membranes are like two-dimensional fluids whose molecules are distributed evenly through lateral diffusion.

26 Apr 2007

New device to test for proteins that play important role in human health and disease

A new technology developed at the University of Toronto is revealing biochemical processes responsible for diseases such as cystic fibrosis and could one day pave the way for pharmaceutical applications.

15 Apr 2007

Scientists discover key player in embryonic muscle development

Muscle fibers are large cells that contain many nuclei. They begin, like all animal cells, as naive embryonic cells. These cells differentiate, producing intermediate cells called myoblasts that are now destined to become muscle.

12 Apr 2007

Analysis of Rhesus monkey genome provides new clues to primate biology

An international consortium of researchers has published the genome sequence of the rhesus macaque monkey and aligned it with the chimpanzee and human genomes.

12 Apr 2007

First measurement of a cellular heartbeat

Researchers have made a breakthrough by detecting the electrical equivalent of a living cell's last gasp. The work takes them a step closer to both seeing the 'heartbeat' of a living cell and a new way to test drugs.

12 Apr 2007

Researchers discover how cells fine-tune oxygen use

Researchers at Johns Hopkins have discovered how cells fine-tune their oxygen use to make do with whatever amount is available at the moment.

7 Apr 2007

No apparent increase in coronary heart disease for women who initiate hormone therapy

Wyeth Pharmaceuticals, a division of Wyeth ( NYSE:WYE ) , provides comment on a re- analysis of pooled data from both hormone therapy arms of the Women's Health Initiative (WHI) Study published today in the Journal of the American Medical Association.

4 Apr 2007

Penn State scientists reveal structure of gateways to gene control

Scientists at Penn State University will reveal in the 29 March 2007 issue of the journal Nature the first complete high-resolution map of important structures that control how genes are packaged and regulated throughout an entire genome.

31 Mar 2007

AACR's Sixth Annual Landon Awards recognize Richard Kolodner, Douglas Lowy and John Schiller

Scientists whose discoveries have led to fundamental advances in the science and treatment of cancer are the recipients of two prestigious international prizes offered by the Kirk A. and Dorothy P. Landon Foundation and the American Association for Cancer Research.

22 Mar 2007

Scientists alter electrical properties of cells inducing regeneration

Scientists at Forsyth may have moved one step closer to regenerating human spinal cord tissue by artificially inducing a frog tadpole to re-grow its tail at a stage in its development when it is normally impossible. Using a variety of methods including a kind of gene therapy, the scientists altered the electrical properties of cells thus inducing regeneration.

28 Feb 2007

Regulator of cholesterol production identified

By first probing the way primitive yeast make cholesterol, a team of scientists has discovered a long-sought protein whose human counterpart controls cholesterol production and potentially drug metabolism.

20 Feb 2007

Determinants of disease presentation and outcome during cryptococcosis

CRNS and the Institut Pasteur conducted research in France on patients diagnosed with cryptococcosis which ranks second among fatal opportunistic infections in patients infected by HIV and who are profoundly immunosuppressed.

12 Feb 2007

Mycology News and Research

New understanding of ubiquitylation

New understanding of infectious prion

Alzheimer's disease, Parkinson's disease, type 2 diabetes similar at the molecular level

New compounds promising candidates for neurodegenerative disease drug development

New vitamin extends lifespan in yeast cells

Scientists discover molecular mechanism that keeps HSV-1 activation restricted to a single gene for months or even years

To live longer - eat less!

Methods for marking molecules to identify gene alterations and metabolic shifts

Important step towards a spatially and temporally quantifiable model of the cell

New device to test for proteins that play important role in human health and disease

Scientists discover key player in embryonic muscle development

Analysis of Rhesus monkey genome provides new clues to primate biology

First measurement of a cellular heartbeat

Researchers discover how cells fine-tune oxygen use

No apparent increase in coronary heart disease for women who initiate hormone therapy

Penn State scientists reveal structure of gateways to gene control

AACR's Sixth Annual Landon Awards recognize Richard Kolodner, Douglas Lowy and John Schiller

Scientists alter electrical properties of cells inducing regeneration

Regulator of cholesterol production identified

Determinants of disease presentation and outcome during cryptococcosis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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