Neglected Tropical Disease News and Research

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Post-infection treatment with NanoViricides FluCide reduces lung lesions caused by lethal influenza infection

NanoViricides, Inc. reports that post-infection treatment with its optimized FluCide™ drug candidates resulted in dramatic reduction in the number of lung lesions that are caused by a lethal influenza virus infection. These findings were seen in the most recent H1N1 influenza animal study.

5 Apr 2011

Recent releases in Global Health

A Lancet Infectious Diseases editorial describes the growing public concerns over a global rise in antimicrobial resistance. "Bearing in mind that our objective is to contain antibiotic resistance rather than eradicate it, several policies could be adopted to help guarantee a future for antibiotics," the editorial states, adding, "We need reliable data to tackle antibiotic resistance.

2 Apr 2011

ISEFC, TB Alliance to establish Global Health R&D Center of China

The International Scientific Exchange Foundation of China, a technical public foundation dedicated to promoting and advancing scientific development, cooperation, and exchange, today signed a Memorandum of Understanding with the Global Alliance for TB Drug Development, to work together to establish the Global Health R&D Center of China, a world-class organization focused on developing innovative new treatments for public health diseases, including tuberculosis, malaria, and HIV/AIDS.

24 Mar 2011

Report finds neglected diseases research funding up in 2009, funding for related non-profits down

"A rise in global funding for research into neglected diseases needs to be matched by a continued focus on delivering practical new ways to curb sickness in the developing world," according to the third annual report by the Global Funding of Innovation for Neglected Diseases released on Wednesday, Reuters reports.

18 Feb 2011

RRD enters partnership with NIH Therapeutics for Rare and Neglected Diseases program

RRD International, a strategy-driven biotech and pharmaceutical product development company, announced today that it has entered into a partnership with the National Institutes of Health (NIH) Therapeutics for Rare and Neglected Diseases (TRND) program as a regulatory support and development partner.

25 Jan 2011

Positive interim data from ongoing V5 Phase IIb imm01 trial against tuberculosis

Immune Network, a company in the business of development and commercialization of immune therapies, announced today that its newly acquired business, Immunitor, has published interim data from the ongoing Phase IIb imm01 clinical trial of V5 in tuberculosis conducted at its second site in Ukraine.

24 Jan 2011

Approaches designed to motivate drug development for children needed

Recent legislative and regulatory actions make great strides toward establishing much needed incentives for pharmaceutical companies and others to develop and test more medications for pediatric rare diseases, including pediatric cancers, according to commentary by experts from Children's National Medical Center. The commentary appears in the January 19 issue of Science Translational Medicine.

21 Jan 2011

RTS,S offers 46 percent protection against malaria for at least 15 months after vaccination, Study finds

A Phase II trial published Friday in Lancet Infectious Diseases has shown that RTS,S, the "experimental malaria vaccine from GlaxoSmithKline provides African children with long-lasting protection" against malaria, Reuters reports.

18 Jan 2011

Opinions: U.S. HIV funding; Global fund accountability; World food supply

President Barack Obama's Global Health Initiative is "pitting AIDS against other diseases by making investments in new areas of global health contingent on flat funding for efforts to fight the HIV epidemic," HIV/AIDS advocate and Yale College student Gregg Gonsalves writes in a Washington Post opinion piece.

18 Jan 2011

Reuters looks at cost-effectiveness of pursuing malaria vaccine, eradication

Reuters examines the effort to create an effective malaria vaccine and asks: "[I]s the vaccine - and the global health community's aim of completely eradicating a disease that kills a child every 45 seconds - really worth the money?"

15 Dec 2010

NIH to create new translational science center

National Institutes of Health (NIH) Director Francis Collins on Tuesday announced the agency is moving forward on plans to create a new research center focused on translational science, after NIH's advisory board voted to create the new center, Science's "Science Insider" blog reports (Kaiser, 12/7).

9 Dec 2010

Campaign to inoculate millions across Africa against meningitis kicks off in Burkina Faso

On Monday, a campaign started in Burkina Faso to "inoculate tens of millions of West Africans with a new vaccine in what scientists hope will be the beginning of the end of ravaging meningitis epidemics" across the continent, the New York Times reports.

7 Dec 2010

IDRI awarded $1.8M contract to develop adjuvant formulations for pandemic influenza

The Infectious Disease Research Institute has been awarded an $1.8 million contract from the Biomedical Advance Research and Development Authority. IDRI's work will focus on development of adjuvant formulations with options up to $8.5 million over three years when further development and manufacture of priority candidates are approved by the agency.

4 Dec 2010

Anacor, UCSF and NYBC collaborate to discover drug therapies for river blindness

Anacor Pharmaceuticals, the University of California San Francisco (UCSF) Sandler Center and the Lindsley F. Kimball Research Institute (LFKRI) of the New York Blood Center (NYBC) today announced the establishment of a research and development collaboration to discover new drug therapies for the treatment of river blindness (onchocerciasis), a parasitic disease that is the second leading cause of infectious blindness worldwide, and is most prevalent in Africa.

1 Dec 2010

Fake antimalarial medications uncovered across Ghana

Substandard and counterfeit versions of thirteen key antimalarial medicines were uncovered in multiple locations across Ghana by the Medicines Quality Monitoring surveillance program. Set up by the Ghana Food and Drugs Board (FDB) in collaboration with the U.S. Pharmacopeial Convention (USP) and the U.S. Agency for International Development (USAID), the program samples antimalarials across the public and private sectors.

9 Nov 2010

Issuing first report on NTDS, WHO aims for 'complete control' by 2015

The WHO said on Thursday that it was aiming for 'complete control' by 2015 of tropical diseases that affect one billion impoverished people and kill an estimated 534,000 people each year, Agence France-Presse reports.

15 Oct 2010

ASTMH recommends FDA to include neglected infections of poverty in orphan classification

Today, U.S. scientists committed to finding answers to reducing and eliminating what are known as neglected tropical diseases (NTDs) that plague the world's poorest people in developing countries, urged the FDA to include in its orphan classification the neglected infections of poverty that also affect Americans, and expressed support for stronger relationships with the FDA to ultimately halt these ancient scourges.

24 Sep 2010

Anonymous Funding promotes drug development for Fragile X syndrome treatment

Funding from an anonymous wealthy family has been the secret to progress, at long last, in developing drugs that show promise for helping millions of people worldwide with Fragile X syndrome, the most common genetic cause of autism. That's the topic of a fascinating article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine.

16 Sep 2010

AAPCHO launches campaign to raise chronic hepatitis B awareness

The U.S. Department of Health and Human Services' Office of Minority Health, the Hepatitis B Foundation and the Association of Asian Pacific Community Health Organizations (AAPCHO) today launched a new campaign to raise awareness of the epidemic of chronic hepatitis B among Americans of Asian and Pacific Islander heritage.

15 Sep 2010

Recent releases in Global Health

In view of World Humanitarian Day, a Huffington Post blog discusses the "lessons" of disaster response and the global "proliferation of humanitarian crises." First, the authors write that "the number of people affected by disasters is on the rise," mostly due to conflict and natural disasters. "Second, and in spite of these trends, U.S. humanitarian assistance is a sound investment. Though only about one-tenth of one percent of the federal budget, our aid not only saves lives, but promotes security and well-being where despair and misery threaten."

21 Aug 2010

Neglected Tropical Disease News and Research

Post-infection treatment with NanoViricides FluCide reduces lung lesions caused by lethal influenza infection

Recent releases in Global Health

ISEFC, TB Alliance to establish Global Health R&D Center of China

Report finds neglected diseases research funding up in 2009, funding for related non-profits down

RRD enters partnership with NIH Therapeutics for Rare and Neglected Diseases program

Positive interim data from ongoing V5 Phase IIb imm01 trial against tuberculosis

Approaches designed to motivate drug development for children needed

RTS,S offers 46 percent protection against malaria for at least 15 months after vaccination, Study finds

Opinions: U.S. HIV funding; Global fund accountability; World food supply

Reuters looks at cost-effectiveness of pursuing malaria vaccine, eradication

NIH to create new translational science center

Campaign to inoculate millions across Africa against meningitis kicks off in Burkina Faso

IDRI awarded $1.8M contract to develop adjuvant formulations for pandemic influenza

Anacor, UCSF and NYBC collaborate to discover drug therapies for river blindness

Fake antimalarial medications uncovered across Ghana

Issuing first report on NTDS, WHO aims for 'complete control' by 2015

ASTMH recommends FDA to include neglected infections of poverty in orphan classification

Anonymous Funding promotes drug development for Fragile X syndrome treatment

AAPCHO launches campaign to raise chronic hepatitis B awareness

Recent releases in Global Health

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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