Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Assessing the safety of inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy children and adolescents

New clinical trial data, recently published in The Lancet’s Infectious Diseases, presents an initial report on the effect of an inactivated SARS-CoV-2 vaccine, CoronaVac, on children and adolescents from ages 3-17 in a double-blind, randomized setting.

30 Jun 2021

BUSM receives $2.7 million grant to reduce disparities in cardio-oncology

With a growing need to better understand the many links between heart disease and cancer, the two leading causes of death worldwide, the American Heart Association, the world's leading voluntary organization dedicated to a world of longer, healthier lives, announced grants focused on this area of scientific research.

29 Jun 2021

New study investigates alternative ways to prevent, treat kidney infections

Ten IU School of Medicine researchers out of a team of 11 scientists, are responsible for the findings of a new study they conducted to investigate alternative ways to treat kidney infections.

29 Jun 2021

Cationic peptides inhibit SARS-CoV-2 cell entry

In a paper recently published in Pathogens, in silico affinity studies by researchers at the University of Illinois, USA, reveal several potential peptide binding sites required for HS-spike protein and ACE2-spike protein bond formation, and synthesis of suitable peptide inhibitors reveals impaired SARS-CoV-2 cell entry.

29 Jun 2021

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Amyloid diseases, including Alzheimer's, Parkinson's, type-2 diabetes and other life-threatening diseases, involve pathologic deposits of normally soluble proteins or peptides as insoluble amyloid fibrils. When this happens in vital organs, such as the brain, kidney, liver and heart, it causes organ damage and, if left untreated, death. Unfortunately, the available treatment options are very limited.

29 Jun 2021

Clinical trial demonstrates safety of new approach to treat invasive kidney cancer

A new approach using precisely targeted, high-dose radiation to treat invasive kidney cancer proves safe, based on a clinical trial by the UT Southwestern Harold C. Simmons Comprehensive Cancer Center's kidney cancer program. The study, published in the International Journal of Radiation Oncology*Biology*Physics, could offer new hope for patients with a historically dismal condition.

29 Jun 2021

New tool allows surgeons to pinpoint breast tumors more easily

Breast surgeons at Hackensack Meridian Hackensack University Medical Center have a new tool that allows them to pinpoint breast tumors more easily, with many benefits to the patient.

29 Jun 2021

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

A new review of the emerging variants of concern (VOCs) of the SARS-CoV-2, which has caused the COVID-19 pandemic, shows that there is a major need to constantly re-evaluate the utility of existing therapeutics and vaccines against the virus and to develop new ones.

28 Jun 2021

Why SARS-CoV-2 delta variant is more infectious

German experts recently explained why the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant is more infectious and pathogenic than its ancestor. By conducting a series of in vitro experiments, they have revealed that increased ability to induce cell-to-cell fusion (syncytia) and reduced susceptibility to vaccine and infection-induced antibodies make the delta variant more infectious than previously circulating variants. The study is currently available on the bioRxiv* preprint server.

28 Jun 2021

UTHSC researchers publish new findings on how obesity impacts cancer treatments

Liza Makowski, PhD, professor in the Department of Medicine and the UTHSC Center for Cancer Research, has long been interested in how the immune system is altered by obesity and how this impacts cancer risk and treatment.

25 Jun 2021

New blood test can accurately detect 50 types of cancer before symptoms emerge

Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher risk of the disease, including patients aged 50 years or older, without symptoms.

25 Jun 2021

Study shows how SARS-CoV-2 virus enters cells to cause infection

Early in the COVID-19 pandemic, scientists identified how SARS-CoV-2, the virus that causes COVID-19, gets inside cells to cause infection.

24 Jun 2021

New microscopy technique reveals the cellular make-up of Wilm's tumors

A new technique to look at tumors under the microscope has revealed the cellular make-up of Wilm's tumors, a childhood kidney cancer, in unprecedented detail.

24 Jun 2021

Study: A subset of patients with localized prostate cancer may benefit from immunotherapies

In recent years, cancer immunotherapy has been effective in treating patients with immunogenic, or so-called "hot" tumors with increased levels of inflammation and the presence of immune cells in and around the tumors.

24 Jun 2021

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

A new study describes the varying ways in which the virus co-opts the machinery of the host cell following infection to evade or modulate the host immune response, alter the pattern of translation of viral proteins, and the release of new viral particles.

24 Jun 2021

Black and Hispanic Americans suffer most in biggest US decline in life expectancy since WWII

Although James Toussaint has never had covid, the pandemic is taking a profound toll on his health.

24 Jun 2021

Researchers identify the origins of seven types of kidney cancer

The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH), the Princess Máxima Center for Pediatric Oncology and Oncode Institute.

24 Jun 2021

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

A new analysis of current data indicates that remdesivir does not show efficacy in regulating the severity of the illness.

23 Jun 2021

In utero exposure to high levels of manganese, selenium may protect children from high blood pressure

Children who were exposed to higher levels of trace minerals manganese and selenium during their mothers' pregnancy had a lower risk of high blood pressure in childhood, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

23 Jun 2021

Study finds higher mortality and lower transplant rates among Black patients with cirrhosis

Black patients with cirrhosis - late-stage liver disease - are about 25% more likely to die compared to non-Hispanic white patients and four times less likely to receive a liver transplant, reports a new Northwestern Medicine study.

23 Jun 2021

Nephrology News and Research

Further Reading

Assessing the safety of inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy children and adolescents

BUSM receives $2.7 million grant to reduce disparities in cardio-oncology

New study investigates alternative ways to prevent, treat kidney infections

Cationic peptides inhibit SARS-CoV-2 cell entry

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Clinical trial demonstrates safety of new approach to treat invasive kidney cancer

New tool allows surgeons to pinpoint breast tumors more easily

Vaccines and drugs must be adapted to combat emerging SARS-CoV-2 variants, says study

Why SARS-CoV-2 delta variant is more infectious

UTHSC researchers publish new findings on how obesity impacts cancer treatments

New blood test can accurately detect 50 types of cancer before symptoms emerge

Study shows how SARS-CoV-2 virus enters cells to cause infection

New microscopy technique reveals the cellular make-up of Wilm's tumors

Study: A subset of patients with localized prostate cancer may benefit from immunotherapies

SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

Black and Hispanic Americans suffer most in biggest US decline in life expectancy since WWII

Researchers identify the origins of seven types of kidney cancer

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

In utero exposure to high levels of manganese, selenium may protect children from high blood pressure

Study finds higher mortality and lower transplant rates among Black patients with cirrhosis

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Expanding research and clinical options for children with cancer

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