Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

One in ten people over 40 in the UK has Type 2 diabetes, new analysis finds

One in ten people over 40 in the UK is now living with a diagnosis of Type 2 diabetes, according to new analysis released today by Diabetes UK. The new figures show that there are 3.8 million people living with a diagnosis of diabetes in the UK, and 90 per cent of those with Type 2.

26 Feb 2019

Pitt engineer wins $500,000 NSF CAREER award to study impact of harmful man-made chemicals

Per- and polyfluorinated alkyl substances are man-made chemicals that are useful in a variety of industries because of their durability, but do not naturally break down in the environment or human body.

26 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

Penn researchers cure nine HCV patients following heart transplants from infected donors

Nine patients at Penn Medicine have been cured of the Hepatitis C virus (HCV) following lifesaving heart transplants from deceased donors who were infected with the disease, according to a study published in the American Journal of Transplantation.

25 Feb 2019

Overweight, obesity in adolescence associated with increased risk of renal cancer later in life

Being overweight has been linked with a higher risk of developing a form of kidney cancer called renal cell carcinoma among adults, but it's unclear if this risk is present during adolescence.

21 Feb 2019

Study: Number of calls to U.S. Poison Control regarding kratom exposure increased

In recent years, kratom has become popular as a treatment for chronic or acute pain as well as mood conditions such as depression and anxiety.

21 Feb 2019

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

The body's ability to adapt to changing conditions and shifting physiologic demands is essential to survival. To do so, each cell must be able to dispose of damaged or unnecessary proteins--a quality-control mechanism critical for cellular performance and for the health of the entire organism.

21 Feb 2019

Johns Hopkins scientists find new compound that may prevent reperfusion injury

In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.

21 Feb 2019

New screening method could catch organ rejection much earlier without a biopsy needle

Too often, it's only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and a urine test could catch rejection much earlier, more comprehensively, and without a biopsy needle.

20 Feb 2019

Newly released national framework identifies obstacles to improving EMS systems

As part of nationwide efforts to improve emergency medical care, researchers at the Mount Sinai Health System, in collaboration with UC San Diego Health, have released a national framework report titled "Promoting Innovations in Emergency Medical Services" that identifies regulatory, financial, and technological obstacles to improving local and state EMS systems.

20 Feb 2019

Common acid reflux drugs tied to elevated risk for kidney disease

Proton pump inhibitors, which include well-known brand names Prilosec, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of adults in the United States take these drugs for frequent heartburn, acid reflux and gastroesophageal reflux disease.

19 Feb 2019

First molecular test predicts treatment response for kidney cancer

Immunotherapy drugs such as PD-L1 checkpoint inhibitors represent the front-line treatment for kidney cancer. But immunotherapy is expensive, benefits only a subset of patients and is futile in the majority of patients.

19 Feb 2019

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease.

19 Feb 2019

Multinational initiative to study familial primary distal renal tubular acidosis

In addition to regulating the body's fluid balance, by excreting greater or smaller amounts of urine, the kidneys also maintain the proper balance of electrolytes (salts) and the pH (an acid-base equilibrium) within our body.

19 Feb 2019

Drug combinations could become first-line treatment for metastatic kidney cancer

A combination of two drugs - one of them an immunotherapy agent - could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

18 Feb 2019

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

The conformance of genetic characteristics is essential for the long-term function after kidney transplantation. This is the central result of a recent study in the top journal “The Lancet” with more than 500 patients after kidney transplantation, conducted by a global consortium led by Rainer Oberbauer and his colleagues Roman Reindl-Schwaighofer and Andreas Heinzel from the Division of Nephrology and Dialysis at MedUni Vienna.

15 Feb 2019

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

$4.1 million funding for heart research on Valentine's Day

Valentine's Day is a time to celebrate love and romance, but the holiday has also become an opportunity to promote heart health, a tradition that continues as Clemson University bioengineers announce the launch of two separate research projects.

14 Feb 2019

Physiological age is a better predictor of survival than chronological age, shows study

It's often said: It's not how old you are, it's how old you feel. New research shows that physiological age is a better predictor of survival than chronological age. The study is published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

14 Feb 2019

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $12.5 million grant from the National Institute on Aging, part of the National Institutes of Health, for a five-year program called the U19 that consists of four multidisciplinary projects in aging biology.

14 Feb 2019

Nephrology News and Research

Further Reading

One in ten people over 40 in the UK has Type 2 diabetes, new analysis finds

Pitt engineer wins $500,000 NSF CAREER award to study impact of harmful man-made chemicals

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

Penn researchers cure nine HCV patients following heart transplants from infected donors

Overweight, obesity in adolescence associated with increased risk of renal cancer later in life

Study: Number of calls to U.S. Poison Control regarding kratom exposure increased

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

Johns Hopkins scientists find new compound that may prevent reperfusion injury

New screening method could catch organ rejection much earlier without a biopsy needle

Newly released national framework identifies obstacles to improving EMS systems

Common acid reflux drugs tied to elevated risk for kidney disease

First molecular test predicts treatment response for kidney cancer

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Multinational initiative to study familial primary distal renal tubular acidosis

Drug combinations could become first-line treatment for metastatic kidney cancer

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

Large-scale clinical trial begins to study liver transplantation between people with HIV

$4.1 million funding for heart research on Valentine's Day

Physiological age is a better predictor of survival than chronological age, shows study

Mount Sinai awarded $12.5 million NIH grant for research program in aging biology

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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