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Genta commences tesetaxel Phase 2b clinical trial as 1st-line chemotherapy for metastatic breast cancer

Genta Incorporated today announced that the Company has initiated a new Phase 2b clinical trial of tesetaxel as 1st-line chemotherapy for women with metastatic breast cancer. Tesetaxel is the leading oral taxane currently in clinical development. The new trial will be conducted at Memorial Sloan-Kettering Cancer Center, New York, NY and at the Accelerated Community Oncology Research Network (ACORN) based in Memphis, TN.

9 Nov 2010

Raptor initiates dosing in DR Cysteamine Phase 2 clinical trial for Huntington's Disease

Raptor Pharmaceutical Corp., today announced that the first patient has been dosed in its Phase 2 clinical trial of DR Cysteamine for the potential treatment of Huntington's Disease. The Phase 2 clinical trial is being conducted under a previously announced collaboration agreement with The Centre Hospitalier Universitaire d'Angers ("CHU d'Angers"), which has commenced enrolling patients at eight clinical sites throughout France.

8 Nov 2010

New findings could help scientists devise optimal therapies for Friedreich's ataxia

Scripps Research Institute scientists have taken a step closer to understanding the cause of Friedreich's ataxia, a debilitating neurological condition that affects tens of thousands of people worldwide, and so far has no cure.

8 Nov 2010

DJOFL third quarter net sales decrease to $233.6 million

DJO Incorporated, a global provider of medical device solutions for musculoskeletal health, vascular health and pain management, today announced financial results for its operating subsidiary, DJO Finance LLC ("DJOFL"), for the third quarter of 2010, ended October 2, 2010.

4 Nov 2010

Aestus receives $244,000 grant from QTDP program

Today Aestus Therapeutics, Inc. announced that it has been awarded a $244,000 grant from the U.S. Government's Qualifying Therapeutic Discovery Project program.

4 Nov 2010

New antibody with SGN-35 drug produces remission in Hodgkin lymphoma

An antibody loaded with an anti-cancer agent produced complete or partial remissions in 38 percent of patients with relapsed or therapy-resistant Hodgkin lymphoma enrolled in a phase I clinical trial, investigators report in the Nov. 4 issue of the New England Journal of Medicine.

4 Nov 2010

Eye implant restores some vision in retinitis pigmentosa

According to a new scientific breakthrough, a device - a tiny, three-by-three millimetre microchip, has allowed patients with inherited blindness to detect objects with their eyes, unlike a rival approach that uses an external camera. The procedure details are outlined in the journal Proceedings of the Royal Society B.

3 Nov 2010

Top 10 Medical Innovations for 2011

From pill-sized cameras to radioactive compounds that let doctors "see" inside a patient's brain, Cleveland Clinic's Top 10 Medical Innovations for 2011 showcases new techniques, therapies and approaches to treating a host of diseases.

3 Nov 2010

Image Guided IMRT preserves sexual function in men after prostatectomy

Men battling prostate cancer who receive Image Guided Intensity Modulated Radiation Therapy after undergoing prostatectomy have an excellent chance of retaining sexual function, according to a study by Allegheny General Hospital (AGH) cancer specialists presented this week at the annual meeting of the American Society for Therapeutic Radiation and Oncology in San Diego.

3 Nov 2010

Eli Lilly's new research center to focus on diabetes in China

Eli Lilly and Company announced today plans to open a research center focused on diabetes in China, where the incidence of the disease has reached epidemic proportions.

2 Nov 2010

OptiNose presents sumatriptan Phase II trial results at 2nd European Headache and Migraine Trust International

OptiNose Inc. announced the results from an analysis comparing the Phase II clinical trial obtained with its novel delivery technology to that of other formulations. The analysis suggests rapid absorption rate alone may not explain the efficacy in migraines treated with sumatriptan delivered with the Company's novel bi-directional technology. The results will be presented at the 2nd European Headache and Migraine Trust International on 28th of October 2010.

30 Oct 2010

Eating disorders negatively affect oral health

While the connection between oral health and systemic health has been well-established, what most people don't know is that dentists often are in a position to detect systemic conditions. According to an article published in the October 2010 issue of AGD Impact, the monthly newsmagazine of the Academy of General Dentistry (AGD), dentists may be the first health care providers to notice evidence of an eating disorder, such as anorexia nervosa, bulimia nervosa, binge eating disorder, and pica.

29 Oct 2010

Pfizer announces approval of Lyrica capsules for peripheral neuropathic pain

Pfizer Inc announced that the Japanese Ministry of Health, Labour and Welfare approved Lyrica (pregabalin) capsules for the treatment of peripheral neuropathic pain. This follows the recent approval in Japan of Lyrica for the treatment of postherpetic neuralgia on April 16, 2010. Lyrica is the first medication approved for peripheral neuropathic pain in Japan where it is co-promoted with Eisai Co., Ltd.

29 Oct 2010

New computer program shows how brain's complex fiber tracks mature as we grow up

The brain's inner network becomes increasingly more efficient as humans mature. Now, for the first time without invasive measures, a joint study from the Ecole Polytechnique F-d-rale de Lausanne (EPFL) and the University of Lausanne (UNIL), in collaboration with Harvard Medical School, has verified these gains with a powerful new computer program. Reported in the PNAS early online edition last week, the soon-to-be-released software allows for individualized maps of vital brain connectivity that could aide in epilepsy and schizophrenia research.

28 Oct 2010

NICE issues PTNS guidance for overactive bladder

Uroplasty, Inc. announced today that the United Kingdom's National Institute for Health and Clinical Excellence (NICE) issued a guidance document titled "Percutaneous Posterior Tibial Nerve Stimulation for Overactive Bladder Syndrome," reinforcing the safety and effectiveness of PTNS for overactive bladder.

28 Oct 2010

Monitoring glucose levels in brain can help predict second-wave of damage in head injury patients

Why do some of the one million people who sustain head injuries annually in United States experience a mysterious second wave of brain damage days after the initial injury - just when they appear to be recovering? Limited clinical trials using an innovative new device to monitor brain chemistry on a second-by-second basis are underway to answer that life-and-death question, according to an article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine. Brain injury is the leading cause of death and disability worldwide.

28 Oct 2010

Researchers develop software tool to study wiring of brains

A team of researchers at the Eindhoven University of Technology has developed a software tool that physicians can use to easily study the wiring of the brains of their patients. The tool converts MRI scans using special techniques to three-dimensional images. This now makes it possible to view a total picture of the winding roads and their contacts without having to operate.

28 Oct 2010

Causes, prevention, and management of inferior alveolar nerve injury during implant dentistry

Although implant dentistry has become widely accepted to restore esthetics and function of teeth, it is not without risks. One serious complication that can occur is alteration of sensation due to nerve injury. Some reports place this occurrence as high as 13%. For dental practitioners, thorough understanding of anatomy, surgical procedures, and implant systems along with proper planning of treatment are essential to reduce this complication.

28 Oct 2010

Advanced procedure for microsurgical breast reconstruction offered at Baptist Health hospitals

When pediatrician Julie A. Buckley, MD, learned that she had breast cancer last year, she chose breast reconstruction using the “DIEP flap” procedure. DIEP (Deep Inferior Epigastric Artery Perforator) flap is available mainly at regional academic centers in the United States.

27 Oct 2010

Diabetes threatens the eyesight of many unsuspecting Americans

Diabetes causes more new cases of legal blindness among working-age Americans than any other disease. If diabetics are monitored regularly by their ophthalmologist, this vision loss is almost always avoidable. Yet, tragically, more than half of all people living with diabetes do not get the recommended annual dilated eye exam. As the number of people with Type 2 diabetes rises in the U.S., the CDC projects that the number of adults with diabetic retinopathy will double by the year 2050. Yet 90 percent of diabetic eye disease can be prevented simply by proper regular examinations and treatment and by controlling blood sugar.

27 Oct 2010

Nerve News and Research

Genta commences tesetaxel Phase 2b clinical trial as 1st-line chemotherapy for metastatic breast cancer

Raptor initiates dosing in DR Cysteamine Phase 2 clinical trial for Huntington's Disease

New findings could help scientists devise optimal therapies for Friedreich's ataxia

DJOFL third quarter net sales decrease to $233.6 million

Aestus receives $244,000 grant from QTDP program

New antibody with SGN-35 drug produces remission in Hodgkin lymphoma

Eye implant restores some vision in retinitis pigmentosa

Top 10 Medical Innovations for 2011

Image Guided IMRT preserves sexual function in men after prostatectomy

Eli Lilly's new research center to focus on diabetes in China

OptiNose presents sumatriptan Phase II trial results at 2nd European Headache and Migraine Trust International

Eating disorders negatively affect oral health

Pfizer announces approval of Lyrica capsules for peripheral neuropathic pain

New computer program shows how brain's complex fiber tracks mature as we grow up

NICE issues PTNS guidance for overactive bladder

Monitoring glucose levels in brain can help predict second-wave of damage in head injury patients

Researchers develop software tool to study wiring of brains

Causes, prevention, and management of inferior alveolar nerve injury during implant dentistry

Advanced procedure for microsurgical breast reconstruction offered at Baptist Health hospitals

Diabetes threatens the eyesight of many unsuspecting Americans

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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