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Mild-mannered organelles can detect virus invasion signals: Researchers

Within cells, an ancient antiviral duo can deliver a one-two knockout to thwart invading viruses, report researchers who have just unmasked the cellular sidekick that throws the first punch. The findings mean scientists must rethink the design of antiviral immunity and how the body fends off viruses of all types, including influenza and HIV.

14 May 2010

New Infrared Relief therapy now available for patients with diabetic neuropathies

Genesis Spine Associates now offers Infrared Relief - a new, highly effective pain management therapy using infrared light for patients suffering from diabetic neuropathies. This new therapy offers a simple, painless option for managing patients' pain without potentially dangerous drugs or surgery.

14 May 2010

Being physical and mental activity delays onset of Huntington’s disease: Research

Melbourne researchers report in a study that regular physical and mental activities can delay the onset of the dreaded genetic Huntington's disease. This disease is hereditary and it goes on to destroy the brain and nerve cells leading to loss of all or most faculties. It affects one in 10,000 people between ages 30 and 50 and there is no cure. Since it is passed on to the children at least 50% of the time the decision to have children also becomes an agonizing one for many sufferers.

13 May 2010

Repligen files IND for Phase 1 study of RG2833 selective HDAC-3 inhibitor for Friedreich's ataxia

Repligen Corporation announced today that it has filed an Investigational New Drug Application (IND) with the Food and Drug Administration (FDA) for a Phase 1 study of RG2833, a selective histone deacetylase 3 (HDAC-3) inhibitor. This is a double-blind, single ascending dose, Phase 1 study in healthy volunteers to evaluate the pharmacokinetic and safety profile of RG2833 in up to 40 subjects.

13 May 2010

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

Regeneron Pharmaceuticals, Inc. (REGN) provided an update on two antibody product candidates in its pipeline and scheduled its first Investor Day to be held in New York City on July 15, 2010. Both product candidates, REGN727 (SAR236553) and, REGN475 (SAR164877) are being developed with sanofi-aventis under a global, strategic collaboration to discover, develop, and commercialize fully human antibodies.

13 May 2010

Daily dose of iron reduces breath-holding spells in children by 90%: Studies

An estimated one in 20 kids suffer from breath-holding spells, which come when they are upset, in pain or surprised. In some cases, the children twitch and jerk around involuntarily, as if they are having a seizure. Their faces sometimes turn blue or pale and they often faint.

12 May 2010

Neurimmune Therapeutics honored with ZKB TECHNOPARK Pioneer Award

The ZKB TECHNOPARK® Pioneer Award, which has been sponsored by the Zürcher Kantonalbank since 2000, was presented for the 20th time at TECHNOPARK® Zurich. The award is given for technological innovations which - thanks to pioneering entrepreneurial achievements - are about to be launched on the market. This year's award winner is Neurimmune Therapeutics AG, represented by Dr. Jan Grimm, Professor Christoph Hock, Professor Roger Nitsch and Dr. Michael Salzmann.

12 May 2010

St. Jude Medical launches Promote Quadra CRT-D in Europe

St. Jude Medical, Inc., a global medical device company, today announced the European launch of its Promote Quadra™ cardiac resynchronization therapy defibrillator (CRT-D). The Promote Quadra CRT-D is the industry's first quadripolar pacing system, which offers physicians the ability to more effectively and efficiently manage the ever-changing pacing needs of patients with heart failure.

12 May 2010

NeuroMetrix first-quarter total revenues decrease to $3.7 million

NeuroMetrix, Inc., a health care company transforming patient care through neurotechnology, today announced its financial results for the three months ended March 31, 2010.

11 May 2010

UCF receives $1.9M NIH grant for exploring new ways of reversing damage caused by MS

A National Institutes of Health grant will help University of Central Florida researchers explore new ways to potentially reverse the damage caused by multiple sclerosis and other neurological disorders.

11 May 2010

Exposure to fine particulate matter can trigger cardiovascular deaths, heart attacks

The scientific evidence linking air pollution to heart attacks, strokes and cardiovascular death has "substantially strengthened," and people, particularly those at high cardiovascular risk, should limit their exposure, according to an updated American Heart Association scientific statement.

11 May 2010

UT Southwestern researchers uncover core function of gene involved in Fragile X syndrome

Researchers at UT Southwestern Medical Center have discovered how the genetic mutation that causes Fragile X syndrome, the most common form of inherited mental retardation, interferes with the "pruning" of nerve connections in the brain. Their findings appear in the April 29 issue of Neuron.

10 May 2010

Majority of Iraq and Afghanistan veterans experience multi-symptom pain disorders

Dr. Gallagher further noted the VA's pain care challenge is magnified by a 90 percent injury survivor rate from these conflicts compared with only 40 percent in the Vietnam War. VA clinicians are now challenged to manage pain in blast survivors with one or several other consequences of blast, such as head injuries causing mild to severe TBI, physical disfigurement and social stigma, emotional trauma, and often post traumatic stress disorder (PTSD).

10 May 2010

Fragile X syndrome iPS cells and embryonic stem cells behave differently: Study

In the last three years, a new technique for reprogramming adult cells has given scientists an easier and less controversial way to harness the power of embryonic-like stem cells to study human disease from its earliest beginnings in hopes of gleaning new insights into the root causes of disease and developing new therapies.

7 May 2010

High resolution ultrasound can be used to evaluate patients with foot drop: Study

High resolution ultrasound should be the imaging test of choice when evaluating patients with foot drop (an inability or difficulty in moving the ankle and toes causing uncontrolled slapping of the foot while taking a step), according to a study to be presented at the ARRS 2010 Annual Meeting in San Diego, CA.

7 May 2010

Inadvertent reprogramming of genes in peripheral nervous system may cause chronic pain

Chronic pain severely limits patients' quality of life and is among the cost drivers in U.S. health care. Patients can suffer pain without an apparent cause and often fail to respond to available treatments. Mayo Clinic researchers and collaborators now report that chronic pain may be caused by the inadvertent reprogramming of more than 2,000 genes in the peripheral nervous system. The research findings appear in the current issue of the journal Genome Research.

7 May 2010

Study highlights benefits of using endometrial stem cells to restore functioning of brain cells

Stem cells derived from the endometrium (uterine lining) and transplanted into the brains of laboratory mice with Parkinson's disease appear to restore functioning of brain cells damaged by the disease, according to a new study by Yale School of Medicine researchers.

7 May 2010

Neurons' complicated tree-like structure formation unravelled

A breakthrough about the formation and maintenance of tree-like nerve cell structures could have future applications in the treatment of neurodegenerative diseases and the repair of injuries in which neurons are damaged. The findings by the international team led by Prof. Benjamin Podbilewicz of the Technion-Israel Institute of Technology Faculty of Biology are published in the May 6th issue of Science Express.

7 May 2010

Survey reveals low awareness of postherpetic neuralgia amongst Americans

The American Pain Foundation (APF) announced today at the American Pain Society (APS) Annual Meeting the results of a national survey that showed postherpetic neuralgia (PHN), also known as after-shingles pain, continues to be a condition with low awareness amongst Americans, demonstrating a need for health care provider (HCP) intervention.

7 May 2010

Preoperative MRI helps spare erectile function, continence after RALP for prostate cancer

Preoperative prostate magnetic resonance imaging (MRI) can help urologic surgeons spare the neurovascular bundle (NVB) (which controls a man's erectile function and continence) during a robotic assisted laparoscopic prostatectomy (RALP) for the treatment of prostate cancer, according to a study to be presented at the ARRS 2010 Annual Meeting in San Diego, CA.

7 May 2010

Nerve News and Research

Mild-mannered organelles can detect virus invasion signals: Researchers

New Infrared Relief therapy now available for patients with diabetic neuropathies

Being physical and mental activity delays onset of Huntington’s disease: Research

Repligen files IND for Phase 1 study of RG2833 selective HDAC-3 inhibitor for Friedreich's ataxia

Regeneron Pharmaceuticals provides update on REGN727, REGN475 antibody product candidates

Daily dose of iron reduces breath-holding spells in children by 90%: Studies

Neurimmune Therapeutics honored with ZKB TECHNOPARK Pioneer Award

St. Jude Medical launches Promote Quadra CRT-D in Europe

NeuroMetrix first-quarter total revenues decrease to $3.7 million

UCF receives $1.9M NIH grant for exploring new ways of reversing damage caused by MS

Exposure to fine particulate matter can trigger cardiovascular deaths, heart attacks

UT Southwestern researchers uncover core function of gene involved in Fragile X syndrome

Majority of Iraq and Afghanistan veterans experience multi-symptom pain disorders

Fragile X syndrome iPS cells and embryonic stem cells behave differently: Study

High resolution ultrasound can be used to evaluate patients with foot drop: Study

Inadvertent reprogramming of genes in peripheral nervous system may cause chronic pain

Study highlights benefits of using endometrial stem cells to restore functioning of brain cells

Neurons' complicated tree-like structure formation unravelled

Survey reveals low awareness of postherpetic neuralgia amongst Americans

Preoperative MRI helps spare erectile function, continence after RALP for prostate cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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