Neural Stem Cells News and Research

RSS

New regulatory code of protein glycosylation

Many proteins in nature exist as glycoproteins, which consist of protein (polypeptide chain) and glycan (sugar chain).

13 Jul 2022

Brain immune response to SARS-CoV-2 infection

In a recently published article in the journal Current Opinion in Neurobiology, scientists at Washington University School of Medicine, St. Louis have described how immunological alterations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may impact brain activities and induce acute and post-acute neurological symptoms in coronavirus disease 2019 (COVID-19) patients.

3 Jul 2022

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Like many neurological diseases, there's a lot we don't understand about fragile X syndrome. But, after studying the disorder for several years, Lynne Maquat's lab knew two important things: the enzyme AKT, which plays a key role in cell growth and survival, and the quality control pathway known as NMD (nonsense-mediated mRNA decay), are both in overdrive in fragile X.

29 Jun 2022

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

We humans lose mental acuity, an unfortunate side effect of aging. And for individuals with neurodegenerative conditions such as Alzheimer's and Parkinson's, the loss of cognitive function often accompanied by mood disorders such as anxiety is a harrowing experience.

16 May 2022

Rutgers study identifies key protein for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, a finding that has important implications for brain health and future therapies for brain disorders.

11 May 2022

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

31 Mar 2022

YME1L protein regulates the production of new nerve cells in the brain

Researchers at the University of Cologne have discovered that the protein YME1L regulates the production of new nerve cells and the maintenance of neural stem cells in the adult brain.

16 Feb 2022

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according to findings published in Proceedings of the National Academy of Sciences.

1 Feb 2022

Nanostructured polymeric scaffolds accelerate neuronal differentiation of neural stem cells

Collaboration between different UPV/EHU departments has achieved a promising advance for future cell therapy: nanostructured scaffolds based on bioresorbable polymers and graphene derivatives that induce aligned migration and accelerate the neuronal differentiation of neural stem cells.

20 Dec 2021

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient.

22 Oct 2021

Study explains how stem cells can help lizards regenerate better tails

Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, the replacement structure is an imperfect cartilage tube.

15 Oct 2021

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Glioblastoma is one of the deadliest cancers known to man. While the advent of immunotherapy and other cutting-edge treatments have prolonged life for people afflicted with other types of cancer, the prognosis for glioblastoma has remained relatively constant: just 18 months.

3 Oct 2021

Stringent lineage tracing is vital for nerve cell regeneration studies

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

29 Sep 2021

Green tea extract and cocoa-supplemented diets improve survival rate of aging mice

Aging-US published "Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system" which reported that green tea extract (GTE) and cocoa-supplemented diets significantly improved the survival rate of mice.

1 Sep 2021

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Aging-US published "PirB functions as an intrinsic suppressor in hippocampal neural stem cells" which reported that neural stem cells play pivotal roles during prenatal development and throughout life.

20 Aug 2021

Researchers create detailed molecular atlas of fetal development of the brain

Researchers at Karolinska Institutet in Sweden have developed a detailed molecular atlas of the fetal development of the brain.

28 Jul 2021

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

20 Jul 2021

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Medical researchers led by Kyushu University have revealed a possible underlying genetic pathway behind the neurological dysfunction of Rett syndrome.

2 Jul 2021

Novel interactions between proteins play a critical role in the brain injury recovery process

Patients with brain injury (caused by stroke or trauma) primarily rely on rehabilitation therapy for recovery, as there are no other known effective treatment methods. The rate of recovery from brain injury observed in adults is significantly slower (or the recovery is impossible) than that observed in young children.

21 Jun 2021

UVA researchers shed new light on brain development

University of Virginia School of Medicine researchers have shed new light on how our brains develop, revealing that the very last step in cell division is crucial for the brain to reach its proper size and function.

31 May 2021