Neuron News and Research

RSS

New drug for melanoma riluzole shows promise

Rutgers Professor Suzie Chen has found that riluzole, a U.S. Food and Drug Administration (FDA) approved drug used to treat Lou Gehrig's disease (ALS), slows the growth of melanoma, the most aggressive form of malignant skin cancer.

16 Apr 2008

New insight into the pathogenesis of neurodegeneration in Ataxia telangiectasia

An upcoming paper from Dr. David Wassarman (University of Wisconsin School of Medicine and Public Health) in the May 1 issue of G&D lends new insight into the pathogenesis of neurodegeneration in Ataxia telangiectasia.

15 Apr 2008

Elevated levels of antioxidant urate may slow Parkinson's progression

Naturally elevated levels of the antioxidant urate may slow the progression of Parkinson's disease in men. Researchers from the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND) and Harvard School of Public Health (HSPH) examined data from an earlier study and found that, among recently diagnosed Parkinson's patients, those with the highest urate levels had a significantly slower rate of disease progression during the two-year study period.

15 Apr 2008

Brain study may lead to improved epilepsy treatments

Using a rodent model of epilepsy, researchers found one of the body's own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain.

15 Apr 2008

Blood urate levels associated with the progression of Parkinson's disease

Higher blood levels of the compound urate, a salt derived from uric acid that is associated with gout, may be associated with a slower progression of Parkinson's disease, according to an article posted online today that will appear in the June 2008 print issue of Archives of Neurology.

15 Apr 2008

Phytochemical-rich foods effective at reversing age-related deficits in memory

If you are getting forgetful as you get older, then a research team from the University of Reading and the Peninsula Medical School in the South West of England may have good news for you.

11 Apr 2008

Researchers close in on origins of main ingredient of Alzheimer's plaques

The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned.

10 Apr 2008

Repeated methamphetamine use causes long-term adaptations in brains of mice

Repeatedly stimulating the mouse brain with methamphetamine depresses important areas of the brain, and those changes can only be undone by re-introducing the drug, according to research at the University of Washington and other institutions.

10 Apr 2008

Omega-3 intake during the last months of pregnancy boosts an infant's development

A study supervised by Universite Laval researchers Gina Muckle and Eric Dewailly reveals that omega-3 intake during the last months of pregnancy boosts an infant's sensory, cognitive, and motor development.

10 Apr 2008

Molecule delivery method improves stem cell differentiation

Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease.

10 Apr 2008

Method to deliver molecules within embryonic stem cells improves differentiation

Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease.

10 Apr 2008

Methamphetamine addiction mechanism discovered

Researchers have identified, for the first time, long-term changes in the brain circuitry of methamphetamine-addicted mice that can explain why the craving of addiction is so stubborn and long-lived.

10 Apr 2008

How protein sludge accumulates in Alzheimer's

Researchers have identified a key mechanism by which the protein sludge that kills brain cells accumulates in Alzheimer's disease (AD).

10 Apr 2008

Diabetes drug may hold potential as treatment for epilepsy, using same mechanism as ketogenic diet

Two years ago, University of Wisconsin-Madison scientists reported they had suppressed epileptic seizures in rats by giving them a glycolytic-inhibitor, inhibiting the brain's ability to turn sugar into excess energy and blocking the expression of seizure-related genes.

9 Apr 2008

Parkinson transplants survive at least 16 years

Transplanted cells can survive in the brain for over one and half decade. However, some of the transplanted cells developed Parkinson-like features which is very surprising.

9 Apr 2008

Identification of dopamine 'mother cells' could lead to future Parkinson's treatments

'Mother cells' which produce the neurons affected by Parkinson's disease have been identified by scientists, according to new research published in the journal Glia.

8 Apr 2008

Leaky blood vessels open up nerve cells to toxic assault In Lou Gehrig's disease

Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience.

7 Apr 2008

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection

As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.

7 Apr 2008

Fetal cells transplanted into the brain to treat Parkinson's may not function long term

Neurons grafted into the brain of a patient with Parkinson's disease fourteen years ago have developed Lewy body pathology, the defining pathology for the disease, according to research by Jeffrey H. Kordower, PhD, and associates and published in the April 6 issue of Nature Medicine.

7 Apr 2008

New potential approach to treat spinal muscular atrophy

In the neuromuscular disease called spinal muscular atrophy, or SMA, a protein deficiency caused by a single gene mutation leads to serious damage in growing nerve cells and the muscles they control.

7 Apr 2008