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Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, University of California, San Francisco (UCSF) medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

20 May 2005

Researchers prevent post-traumatic brain damage using experimental drug

In animal studies, researchers from Georgetown University Medical Center have shown how traumatic brain injury leads to loss of brain function - and found that an experimental drug can stop the damage and promote recovery.

18 May 2005

Vaccine candidate to treat nicotine addiction shows promise

Cytos Biotechnology AG has announced that its vaccine candidate CYT002-NicQb to treat nicotine addiction has achieved proof of efficacy.

16 May 2005

Common antibiotic called minocycline may slow or prevent diabetic retinopathy

The team found that minocycline, often used to treat acne, limits by about 50 percent the retinal damage caused by microglia. Microglia are cells that act as the "cleanup crew" for the Central Nervous System (CNS).

11 May 2005

Magnetic stimulation treatment for depression

Barbara Baas ran away from home and tried to kill herself as a teenager. As an adult, she has tried more than 15 varieties of antidepressants. But, thanks to a new weapon, she has finally reached a truce in a 45-year battle.

10 May 2005

Discovery reveals how stem cells can be used to help repair acute spinal cord damage

A treatment derived from human embryonic stem cells improves mobility in rats with spinal cord injuries, providing the first physical evidence that the therapeutic use of these cells can help restore motor skills lost from acute spinal cord tissue damage.

10 May 2005

Research proves the dangers of salt

Sydney University scientists have proved that salt has a dangerous adrenalin-inducing effect on people suffering from high blood pressure, or 'hypertension'.

10 May 2005

"Anxiety Gene" linked to depression, makes the body out of tune

U.S. scientists in viewing the human body as a well-tuned orchestra, say that think they may have found a discordant note in the form of a gene which appears to increase the likelihood of some people developing anxiety and depression.

9 May 2005

Suspect gene may increase susceptibility to anxiety and depression

People with the depression-linked gene variant showed less gray matter and weaker connections in the mood-regulating circuit. How well the circuit was connected accounted for nearly 30 percent of their anxious temperament

8 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

Does clinical depression bring about chronic pain? Or does pain lead to depression?

Does clinical depression bring about chronic pain? Or does pain lead to depression? Because these two conditions frequently co-exist--30 to 54 percent of patients with major depressive disorder also suffer persistent physical pain--there has been much speculation about whether one causes the other or whether a common underlying factor provokes both. Results of studies into the precise nature of this relationship, however, have been inconsistent.

5 May 2005

The humble snail is helping scientists explore ways of treating memory loss in humans

Drug manufacturers are looking at ways to create a "Viagra for the brain", which could alleviate memory loss, one of the distressing symptoms of diseases such as Alzheimer's. Work carried out by Dr George Kemenes, Senior Fellow in the Department of Biology and Environmental Science at the University of Sussex, will hopefully help to show how such drugs could work.

4 May 2005

Study reveals new approach to Huntington's disease

Scientific theory holds that Huntington's disease (HD) is caused by a mutant protein that arises within brain cells and kills them, triggering the genetic neurological disorder. Now a new UCLA Neuropsychiatric Institute study reveals the first strong evidence that the mutant protein also elicits toxic interactions from neighboring cells to provoke the fatal brain disorder. The May 5 edition of Neuron reports the findings.

4 May 2005

Glucose byproduct prevents brain damage after diabetic coma

A natural, non-toxic byproduct of glucose may prevent brain cell death and cognitive impairment in diabetics following an episode of severely low blood sugar, according to researchers at the San Francisco VA Medical Center (SFVAMC).

4 May 2005

Potential for brain stem cells to be used to cure diabetes

Promising new research by US scientists has shown the potential for brain stem cells to be used to cure diabetes. The work by Stanford University researchers, though not yet ready to be tested on human patients, has shown promising results in animals.

28 Apr 2005

Clues about the causes of dementia in Huntington's disease

Scientists at Melbourne's Howard Florey Institute have uncovered a clue about the causes of dementia in Huntington's disease, one of the disease's symptoms, by showing that mice susceptible to Huntington's disease have problems with learning and memory before the diseases' typical movement problems appear.

27 Apr 2005

Researchers zero in on sleep gene

Zeroing in on the core cellular mechanisms of sleep, researchers at University of Wisconsin Medical School have identified for the first time a single gene mutation that has a powerful effect on the amount of time fruit flies sleep.

27 Apr 2005

Natural glucose byproduct prevents brain damage and cognitive impairment after diabetic coma

27 Apr 2005

Moderate alcohol consumption enhances the formation of new nerve cells

Moderate alcohol consumption over a relatively long period of time can enhance the formation of new nerve cells in the adult brain. The new cells could prove important in the development of alcohol dependency and other long-term effects of alcohol on the brain. The findings are published by Karolinska Institutet.

26 Apr 2005

Substantially more effective therapy than current treatments for Alzheimer's disease

PET scans and cognitive tests have suggested that Alzheimer's disease patients with genetically modified tissue inserted directly into their brains show a reduction in the rate of cognitive decline and increased metabolic activity in the brain, according to a study published in the April 24, 2005 online issue of the journal Nature Medicine by researchers at the University of California, San Diego (UCSD) School of Medicine.

25 Apr 2005