Neurons News and Research

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Scientists focus on the role of mutated adult neural stem cells play in human diseases

CHARGE syndrome* is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the broad spectrum of characteristic CHARGE symptoms has been a mystery.

6 Jul 2013

Epigenome mapping uncovers unique patterns that emerge during generation of brain circuitry

High-resolution mapping of the epigenome has discovered unique patterns that emerge during the generation of brain circuitry in childhood.

6 Jul 2013

Findings uncover epigenomic modification that occurs during brain formation

Changes in the epigenome, including chemical modifications of DNA, can act as an extra layer of information in the genome, and are thought to play a role in learning and memory, as well as in age-related cognitive decline.

5 Jul 2013

Physical activity reduces stress and promotes growth of new neurons

Physical activity reorganizes the brain so that its response to stress is reduced and anxiety is less likely to interfere with normal brain function, according to a research team based at Princeton University.

5 Jul 2013

Research: People's frontal cortex undergoes a significant change from infancy to adolescence

Experience of parents with their children and teachers with their students demonstrate how kids change their behaviours and knowledge from infancy to adolescence. Until now, little was known of the causes that could lead to these changes.

5 Jul 2013

Study shows possible biological cause of narcolepsy

In 2000, researchers at the UCLA Center for Sleep Research published findings showing that people suffering from narcolepsy, a disorder characterized by uncontrollable periods of deep sleep, had 90 percent fewer neurons containing the neuropeptide hypocretin in their brains than healthy people.

4 Jul 2013

Study: Different strains of alpha-synuclein may contribute to different types of brain diseases

It only takes one bad apple to spoil the bunch, and the same may be true of certain proteins in the brain. Studies have suggested that just one rogue protein (in this case, a protein that is misfolded or shaped the wrong way) can act as a seed, leading to the misfolding of nearby proteins.

4 Jul 2013

Salk studies pave way to better computer object recognition and therapies for visual disorders

How is it possible for a human eye to figure out letters that are twisted and looped in crazy directions, like those in the little security test internet users are often given on websites?

3 Jul 2013

Researchers develop stimulation technique to improve language function in stroke patients with aphasia

On July 2nd, JoVE will publish a video article showing the details of a technique developed by researchers to improve language function in stroke patients with chronic speech-language impairment.

3 Jul 2013

Researchers pinpoint role of Arl13b gene in guiding placement of neurons during brain development

Researchers have pinpointed the role of a gene known as Arl13b in guiding the formation and proper placement of neurons in the early stages of brain development. Mutations in the gene could help explain brain malformations often seen in neurodevelopmental disorders.

3 Jul 2013

FDA-approved formoterol drug improves cognitive function in mouse model of Down syndrome

An existing FDA-approved drug improves cognitive function in a mouse model of Down syndrome, according to a new study by researchers at the Stanford University School of Medicine.

3 Jul 2013

Scientists find new links in gene networks that control movement

The idea that worms can be seen as waveforms allowed scientists at Rice University to find new links in gene networks that control movement.

2 Jul 2013

Study suggests patient's neurons may be altered in different ways, although resulting disease is same

Epilepsy, irregular heartbeats and other conditions caused by malfunctions in the body's nerve cells, also known as neurons, can be difficult to treat. The problem is that one medicine may help some patients but not others.

2 Jul 2013

Researchers find new treatment option for schizophrenia

A research group led by professor Jesper Ekelund showed that by giving a very large dose of famotidine (200 mg daily), sufficient amounts of the drug are able to penetrate the so-called blood-brain barrier to affect the histamine system in the brain.

1 Jul 2013

Scientists identify neuronal circuits in spinal cord control limb alternation during walking

Scientists at Karolinska Institutet in Sweden have identified the neuronal circuits in the spinal cord of mice that control the ability to produce the alternating movements of the legs during walking.

1 Jul 2013

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

A team of researchers from Rush University, Yale University, the University of Colorado and the St. Kitts Biomedical Research Foundation transplanted human embryonic stem cells into primate laboratory animals modeled with Parkinson's disease and found "robust survival" of the cells after six weeks and indications that the cells were "well integrated" into the host animals.

29 Jun 2013

Scientists use brain-tracing technique to untangle circuitry that guides brain function

The power of the brain lies in its trillions of intercellular connections, called synapses that together form complex neural "networks." While neuroscientists have long sought to map these individual connections to see how they influence specific brain functions, traditional techniques have been unsuccessful.

28 Jun 2013

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find. A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta (Αβ) plaques that are associated with Alzheimer's disease, a study by researchers with the UC Davis Alzheimer's Disease Center has found.

28 Jun 2013

Study examines role of six-layered cerebral cortex in processing sensory information

A series of studies conducted by Randy Bruno, PhD, and Christine Constantinople, PhD, of Columbia University's Department of Neuroscience, topples convention by showing that sensory information travels to two places at once: not only to the brain's mid-layer (where most axons lead), but also directly to its deeper layers. The study appears in the June 28, 2013, edition of the journal Science.

28 Jun 2013

Mouse models demonstrate new potential target in fight against Alzheimer's disease

Building on research published eight years ago in the journal Chemistry and Biology, Kenneth S. Kosik, Harriman Professor in Neuroscience and co-director of the Neuroscience Research Institute (NRI) at UC Santa Barbara, and his team have now applied their findings to two distinct, well-known mouse models, demonstrating a new potential target in the fight against Alzheimer's and other neurodegenerative diseases.

27 Jun 2013

Neurons News and Research

Scientists focus on the role of mutated adult neural stem cells play in human diseases

Epigenome mapping uncovers unique patterns that emerge during generation of brain circuitry

Findings uncover epigenomic modification that occurs during brain formation

Physical activity reduces stress and promotes growth of new neurons

Research: People's frontal cortex undergoes a significant change from infancy to adolescence

Study shows possible biological cause of narcolepsy

Study: Different strains of alpha-synuclein may contribute to different types of brain diseases

Salk studies pave way to better computer object recognition and therapies for visual disorders

Researchers develop stimulation technique to improve language function in stroke patients with aphasia

Researchers pinpoint role of Arl13b gene in guiding placement of neurons during brain development

FDA-approved formoterol drug improves cognitive function in mouse model of Down syndrome

Scientists find new links in gene networks that control movement

Study suggests patient's neurons may be altered in different ways, although resulting disease is same

Researchers find new treatment option for schizophrenia

Scientists identify neuronal circuits in spinal cord control limb alternation during walking

Study: Pluripotent stem cell line-derived neurons survive and respond to cues in the primate brain

Scientists use brain-tracing technique to untangle circuitry that guides brain function

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

Study examines role of six-layered cerebral cortex in processing sensory information

Mouse models demonstrate new potential target in fight against Alzheimer's disease

Neuroscience - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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