Neuropsychopharmacology News and Research

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Stable sleep patterns and regular routines may improve outcomes in bipolar disorder

Bipolar disorder, commonly known as manic-depressive disorder, is highly influenced by the circadian system - the body's internal clock - and a specific kind of psychotherapy may help decrease irregularities in the circadian system that can trigger key symptoms of bipolar disorder, according to a study presented at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

Possible genetic link between schizophrenia and cancer

A series of studies presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting elucidates evidence that there is a genetic link between schizophrenia and cancer, providing a surprising possible scientific explanation for lower rates of cancer among patients with schizophrenia – despite having poor diets and high rates of smoking – and their parents.

10 Dec 2007

Depression nearly triples the risk of death following a heart attack

...even when accounting for other heart attack risk factors, according to research presented at the American College of Neuropsychopharmacology (ACNP) annual meeting, which showed that among 360 depressed, post myocardial infarction patients followed for more than six years, those who did not recover from their depression in the first six months were more than twice as likely to die.

10 Dec 2007

Brain overgrowth in 1-year-olds linked to development of autism

Brain overgrowth in the latter part of an infant's first year may contribute to the onset of autistic characteristics, according to research presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

Mental disorders are disorders of the brain

Depression, anxiety disorders such as panic disorder and obsessive-compulsive disorders, alcohol and drug dependence, dementia and Parkinson's disease are just a few examples of "disorders of the brain".

17 Oct 2007

Women with anorexia taste different!

Although anorexia nervosa is categorized as an eating disorder, it is not known whether there are alterations of the portions of the brain that regulate appetite.

26 Sep 2007

Women more prone to brain damage from alcohol abuse than men

Alcoholism has traditionally been considered a male disease because there are many more alcoholic males than females.

27 Jul 2007

New hope for people with therapy-resistant depression

A study at the University Clinics of Bonn and Cologne gives people with therapy-resistant depression reason for hope.

19 Apr 2007

Acne drug leads to depression-related behavior in mice

A drug commonly used to treat severe acne can lead to depression-related behavior in mice, according to research published in the journal Neuropsychopharmacology by scientists from The University of Texas at Austin and the University of Bath.

21 Sep 2006

Acne drug Roaccutane linked to depression

A drug commonly used to treat severe acne can lead to depressive behaviour in mice, according to research published in the journal Neuropsychopharmacology.

19 Sep 2006

Neuropsychopharmacology editor resigns after failure to disclose conflict of interest

Charles Nemeroff has decided to resign as editor of the journal Neuropsychopharmacology after he co-authored a favorable article on a chest implant that treats depression and did not disclose his financial ties to Cyberonics, which manufactures the device, the Wall Street Journal reports.

30 Aug 2006

Link between expectancy, visual cues and the desire to smoke

In a study recently published in the journal Neuropsychopharmacology, researchers at the Montreal Neurological Institute (MNI) and the Department of Psychology at McGill University found that when people expect to smoke in the near future, external cues such as watching someone smoke affects their brain more than their level of craving or how long they have gone without a cigarette.

23 Apr 2006

Profound alterations in the brain mechanisms that regulate motivated behavior with addiction

Rats that have a strong craving for cocaine have a different biochemical response to the drug than their less-addicted counterparts, researchers at UT Southwestern Medical Center have found.

15 Mar 2006

Nicotine has an unusual psychological property that may drive dependence

Associate Professor Athina Markou, Ph.D., who is in the Scripps Research Molecular and Integrative Neurosciences Department at Scripps Research’s La Jolla Campus, and Paul Kenny, Ph.D., a former Research Associate in her laboratory, report in an upcoming issue of the journal Neuropsychopharmacology that nicotine has an unusual psychological property that may drive dependence.

28 Sep 2005

Genetic makeup may detemine likely success of quit smoking therapies

A study by researchers at the Transdisciplinary Tobacco Use Research Center (TTURC) of the University of Pennsylvania School of Medicine indicates that a smoker's genetic make-up may affect whether they quit or not while using either bupropion (Zyban) or nicotine replacement therapies (NRTs) such as the nicotine patch or nasal spray.

30 Aug 2005

Teenage drug use can lead to adult addiction and heart attack

A new study from the Howard Florey Institute in Melbourne may help explain why people who experimented with amphetamines, such as 'speed', as teenagers are more likely to become addicted and more susceptible to heart attack following re-use of the drug as adults.

30 Aug 2005

Overactive dopamine receptors may help explain anorexia nervosa symptoms

Just why those with anorexia nervosa are driven to be excessively thin and seem unaware of the seriousness of their condition could be due to over-activity of a chemical system found in a region deep inside the brain, a University of Pittsburgh study suggests.

11 Jul 2005

Findings suggest important differences among smokers in brain responses that underlie the smoking habit

Not all smokers are alike when it comes to cravings, and a new study conducted by researchers at Duke University Medical Center suggests the difference may lie in their brains' sensitivity to drug cues.

29 Jun 2005

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

An experimental drug combined with an already-popular memory-enhancing compound may further delay memory loss in patients with Alzheimer's disease and other dementias, Johns Hopkins University scientists, in collaboration with researchers from University of North Carolina, have found.

9 Jun 2005

Finding opens new doors to determining susceptibility to antidepressant side effects

In a finding that opens new doors to determining susceptibility to antidepressant side effects, researchers at the UCLA Neuropsychiatric Institute report that changes in brain activity prior to treatment with antidepressants can flag patient vulnerability.

30 Mar 2005