Neuropsychopharmacology News and Research

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New tool to detect Alzheimer's early

Doctors have long known that smell is one of the first senses to fail as Alzheimer's begins its slow and incurable progression. Tracking the process whereby a person loses their ability to smell could play a pivotal role in early detection and treatment of Alzheimer's. And now researchers at Columbia have developed a tool that will aid early detection.

12 Jan 2005

Modafinil may be a possible medicinal treatment for cocaine dependence

Cocaine dependence is a major public health problem affecting thousands of people around the globe. Despite years of active research there are still no approved medications for the treatment of this life-shattering addiction.

10 Jan 2005

Odor identification test, strong predictor of Alzheimer's Disease

The inability to identify the smell of lemons, lilac, leather and seven other odors predicts which patients with minimal to mild cognitive impairment (MMCI) will develop Alzheimer's Disease, according to a study presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting.

13 Dec 2004

Early ritalin may cause long-term effects on the brain

A new study conducted in rats by the National Institutes of Health (NIH) and McLean Hospital/Harvard Medical School suggests that the misdiagnosis of attention-deficit hyperactivity disorder (ADHD) combined with prescription drug use in children may lead to a higher risk of developing depressive symptoms in adulthood.

13 Dec 2004

Cigarette smoking can dramatically affect appetite and weight control

The study by researchers in the Department of Pharmacology and the CRC for Chronic Inflammatory Diseases found that mice exposed to four days of cigarette smoke displayed significant loss of appetite, fat tissue and body weight.

1 Nov 2004

Acetaldehyde appears to increase the addictive properties of nicotine

Acetaldehyde, one of the main chemical components of tobacco smoke, appears to increase the addictive properties of nicotine, according to animal studies conducted by the UC Irvine Transdisciplinary Tobacco Use Research Center (TTURC).

29 Oct 2004

Cocaine addicts experience a decrease in D2 receptors affecting brain regions involved with movement, as well as motivation

A new study builds on previous research showing that cocaine-addicted people have a low expression of specific dopamine receptors—D2 receptors—in a portion of the brain called the striatum.

6 Oct 2004