Neuropsychopharmacology News and Research

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Study sheds light on the mechanisms of brain plasticity induced by fluoxetine

A recent study, published in Neuropsychopharmacology, conducted by researchers from the University of Helsinki and the University of Eastern Finland, sheds light on the mechanisms of neural plasticity induced by the antidepressant fluoxetine.

5 Apr 2023

Researchers use the drug fasudil to reverse two key symptoms of schizophrenia

A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of pyramidal neurons and cognitive dysfunction associated with methamphetamine treatment.

17 Feb 2023

Scientists reveal why common anti-depressants cause emotional ‘blunting’ in users

Scientists have worked out why common anti-depressants cause around a half of users to feel emotionally 'blunted'.

23 Jan 2023

Common psychiatric medications can give some protection against COVID-19

A new meta-analysis shows that psychiatric medications can give some protection against COVID-19, with the common antidepressant fluvoxamine showing the strongest effect.

16 Dec 2022

Johns Hopkins researchers characterize a broad range of psychedelic occasioned belief changes

Johns Hopkins Medicine researchers continue their exploration into psychedelics and how these drugs may produce a wide range of profound changes in perception, cognition and mood.

9 Dec 2022

Scientists identify a class of drugs that may prevent alcohol use disorder in people with PTSD

Survivors of abuse and trauma are vastly more likely than other people to develop alcohol use disorder (AUD); according to some estimates, as many as three-quarters of people with post-traumatic stress disorder (PTSD) report drinking problems.

21 Nov 2022

Does CBD mitigate harms of cannabis?

Researchers examine adverse outcomes of THC could be alleviated by increasing the concentrations of CBD in these products.

20 Nov 2022

Understanding the brain correlates of dissociative disorders

Trauma can cause dissociative symptoms-;such as having an out-of-body experience, or feeling emotionally numb-;that may help an individual cope in the short term but can have negative impacts if the symptoms persist for a long period of time.

3 Nov 2022

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Alzheimer's disease (AD), characterized by an accumulation of β-amyloid protein (Aβ) in brain tissue, is a leading cause of dementia.

24 Oct 2022

COVID pandemic saw a huge drop in patients seeking treatment for clinical depression

In the first study of its kind, German researchers have shown that the COVID pandemic saw a huge drop in the number of patients being admitted to hospital for clinical depression.

17 Oct 2022

Heart medication may also be effective for treating alcohol use disorder

A medication for heart problems and high blood pressure may also be effective for treating alcohol use disorder, according to a new study by researchers at the National Institutes of Health and their colleagues.

20 Sep 2022

Johns Hopkins researchers explore the link between psychedelics and consciousness

Psychedelic drugs, like psilocybin, an ingredient found in so-called magic mushrooms, have shown promise in treating a range of addictions and mental health disorders.

31 Mar 2022

European research project focuses on fighting against new psychoactive drugs

Promoting the fight against the use of drugs of abuse, anticipating to the appearance of new psychoactive drugs and assessing the risks these have on human health are the main objectives of the European research project approved by the European Commission and led by the Research Group on Neuropsychopharmacology of Amphetamine Derivatives of the University of Barcelona.

21 Feb 2022

Two doses of psilocybin may ease depression symptoms for up to 12 months

Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month.

15 Feb 2022

Researchers identify gene expression signatures linked to suicide risk

Is risk of suicide in our genes? Findings of an international scientific team led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that gene expression studies could offer insights into the underlying causes of suicide, a highly complex public health problem that takes the lives of more than 800,000 people each year worldwide.

10 Jan 2022

$15 million gift to fund undergraduate programs and graduate student fellowships in life sciences

A decades-long friendship and a shared passion for basic science has inspired a $15 million gift to the Division of Biology & Biomedical Sciences (DBBS) at Washington University in St. Louis to fund undergraduate programs and graduate student fellowships in the life sciences.

30 Oct 2021

EQIPD consortium develops quality system to facilitate adherence to evidence-based research practices

The European Quality in Preclinical Data (EQIPD) consortium has announced the official finalisation of the EQIPD Innovative Medicines Initiative (IMI) project.

12 Oct 2021

Psychedelic drug changes the emotional state of people listening to music

Scientists have found that the psychedelic drug psilocybin, in development as an anti-depressive treatment, changes the emotional state of people listening to music.

4 Oct 2021

Post-COVID depressive symptoms respond well to antidepressants, study shows

The COVID pandemic has led to a significant increase in mental health problems. Now, in some good news, a pilot study has shown that depressed patients who have suffered from COVID respond better to standard antidepressants than do people who have not had COVID.

4 Oct 2021

Existing drug used to treat constipation may boost people's ability to think more clearly

The development of drugs to treat cognitive problems in patients with mental illness may be a step closer after a team of researchers discovered that an existing drug - used to treat constipation - may be able to boost our ability to think more clearly.

4 Oct 2021

Neuropsychopharmacology News and Research

Study sheds light on the mechanisms of brain plasticity induced by fluoxetine

Researchers use the drug fasudil to reverse two key symptoms of schizophrenia

Scientists reveal why common anti-depressants cause emotional ‘blunting’ in users

Common psychiatric medications can give some protection against COVID-19

Johns Hopkins researchers characterize a broad range of psychedelic occasioned belief changes

Scientists identify a class of drugs that may prevent alcohol use disorder in people with PTSD

Does CBD mitigate harms of cannabis?

Understanding the brain correlates of dissociative disorders

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

COVID pandemic saw a huge drop in patients seeking treatment for clinical depression

Heart medication may also be effective for treating alcohol use disorder

Johns Hopkins researchers explore the link between psychedelics and consciousness

European research project focuses on fighting against new psychoactive drugs

Two doses of psilocybin may ease depression symptoms for up to 12 months

Researchers identify gene expression signatures linked to suicide risk

$15 million gift to fund undergraduate programs and graduate student fellowships in life sciences

EQIPD consortium develops quality system to facilitate adherence to evidence-based research practices

Psychedelic drug changes the emotional state of people listening to music

Post-COVID depressive symptoms respond well to antidepressants, study shows

Existing drug used to treat constipation may boost people's ability to think more clearly

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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