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Scientists discover first selective inhibitors of DAGL enzymes

Scientists at The Scripps Research Institute (TSRI) have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known as diacylglycerol lipases (DAGL), their products, and the pathways they regulate.

1 Nov 2012

BWH researchers propose new model that shifts how we think about mindfulness

Achieving mindfulness through meditation has helped people maintain a healthy mind by quelling negative emotions and thoughts, such as desire, anger and anxiety, and encouraging more positive dispositions such as compassion, empathy and forgiveness. Those who have reaped the benefits of mindfulness know that it works. But how exactly does it work?

31 Oct 2012

Empathetic and analytic thinking mutually exclusive in the brain

New research shows a simple reason why even the most intelligent, complex brains can be taken by a swindler's story - one that upon a second look offers clues it was false.

31 Oct 2012

Lateral intraparietal area in the brain activates internal sensors to help keep time

Researchers at the University of Minnesota's Center for Magnetic Resonance Research (CMRR) have found a small population of neurons that is involved in measuring time, which is a process that has traditionally been difficult to study in the lab.

31 Oct 2012

Animals adjust their sense of smell through sniffing techniques

Animals use their noses to focus their sense of smell, much the same way that humans focus their eyes, new research at the University of Chicago shows.

31 Oct 2012

Viewpoints: Friedman on why Democrats are really the 'pro-life' party; Myths about doctor-assisted suicide

Hard-line conservatives have gone to new extremes lately in opposing abortion. ... These are the authentic voices of an ever-more-assertive far-right Republican base that is intent on using uncompromising positions on abortion to not only unseat more centrist Republicans ... but to overturn the mainstream consensus in America on this issue.

30 Oct 2012

Children with migraine more likely to have below average school performance

Children with migraine are more likely to have below average school performance than kids who do not have headaches, according to new research published in the October 30, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

30 Oct 2012

Ultra-high performance SPECT systems announced by MILabs

MILabs, B.V. the Netherlands‐based innovator and manufacturer of pre‐clinical SPECT/PET/CT imaging devices announces the release of the Plus! Systems: the U‐SPECT+ and U‐SPECT+ /CT.

29 Oct 2012

AstraZeneca commences FASLODEX Phase III study for hormone receptor-positive metastatic breast cancer

AstraZeneca today announced the start of a Phase III study (FALCON), a global clinical trial which will involve 450 postmenopausal patients with hormone receptor-positive locally advanced or metastatic breast cancer who have not previously been treated with any hormonal therapy. The Phase III study is designed to evaluate the efficacy and tolerability of fulvestrant 500 mg compared to anastrozole 1 mg in this patient population.

29 Oct 2012

Homocysteine not linked to cognition in FEP

Patients experiencing a first episode of psychosis have significantly higher homocysteine levels than mentally healthy individuals, researchers report.

26 Oct 2012

Highlights from 25th European College of Neuropsychopharmacology Congress

In the course of the 25th ECNP Congress leading experts and five and a half thousand psychiatrists, neurologists, neuroscience researchers and public health professionals from over 90 different countries met from 13 to 17 October 2012 in Vienna, Austria, to celebrate ECNP´s 25-year anniversary and engage in groundbreaking debate.

26 Oct 2012

Study defines complexity of underlying mutations responsible for pancreatic cancers

A large-scale study that defines the complexity of underlying mutations responsible for pancreatic cancers in more than 100 patients was published in Nature today.

26 Oct 2012

Omega-3 fatty acid can enhance cognition in highly functional young individuals

While Omega-3 essential fatty acids-found in foods like wild fish and grass-fed livestock-are necessary for human body functioning, their effects on the working memory of healthy young adults have not been studied until now.

26 Oct 2012

Simple approach results in low rates of MRSA infections

High compliance with hand hygiene and focusing on other simple infection control measures on medical, surgical and neuroscience intensive care units resulted in reduced rates of methicillin-resistant Staphylococcus aureus (MRSA) infection by 95 percent in a nine-year study, according to research findings by Virginia Commonwealth University physicians presented during IDWeek 2012.

26 Oct 2012

Kessler Foundation expert to study effects of prism adaptation therapy for spatial neglect

A.M. Barrett, MD, of Kessler Foundation received a grant totaling $595,756 to study the effects of prism adaptation therapy for spatial neglect in survivors of right-sided stroke.

25 Oct 2012

Anterior insular cortex associated with human empathy

An international team led by researchers at Mount Sinai School of Medicine in New York has for the first time shown that one area of the brain, called the anterior insular cortex, is the activity center of human empathy, whereas other areas of the brain are not. The study is published in the September 2012 issue of the journal Brain.

25 Oct 2012

Social or daily drinking may be more harmful to brain health

Drinking a couple of glasses of wine each day has generally been considered a good way to promote cardiovascular and brain health. But a new Rutgers University study indicates that there is a fine line between moderate and binge drinking - a risky behavior that can decrease the making of adult brain cells by as much as 40 percent.

25 Oct 2012

Novel approach to assemble the 'connectome' via genetic barcoding

A team of neuroscientists has proposed a new and potentially revolutionary way of obtaining a neuronal connectivity map (the "connectome") of the whole brain of the mouse. The details are set forth in an essay published October 23 in the open-access journal PLOS Biology.

24 Oct 2012

Kessler Foundation to study role of environmental factors in rehabilitation outcomes in SCI

Amanda Botticello, PhD, MPH, research scientist in Outcomes & Assessment Research at Kessler Foundation, received a National Institutes of Health (NIH) grant to study the role of environmental factors in rehabilitation outcomes in spinal cord injury.

24 Oct 2012

Exendin-4 could effectively treat addiction

Vanderbilt researchers are reporting today that a drug currently used to treat type 2 diabetes could be just as effective in treating addiction to drugs, including cocaine.

24 Oct 2012