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Study links sea sponge genome sequence with first animals and cancer

The sponge, which was not recognized as an animal until the 19th century, is now the simplest and most ancient group of animals to have their genome sequenced. In a paper appearing in the August 5 issue of the journal Nature, a team of researchers led by Daniel Rokhsar of the University of California, Berkeley, and the Department of Energy's Joint Genome Institute (JGI), report the draft genome sequence of the sea sponge Amphimedon queenslandica and several insights the genome gives into the origins of both the first animals and cancer.

5 Aug 2010

Detection of Alzheimer's before symptoms occur

Research is on to detect the dreaded Alzheimer's disease even before any symptoms occur. In a newly proposed diagnostic criteria developed by experts from the National Institute on Aging and the Alzheimer's Association three stages of the disease viz. pre-clinical Alzheimer's, mild cognitive impairment and Alzheimer's dementia are described.

4 Aug 2010

Influence of culture on brain structure and function

Where you grow up can have a big impact on the food you eat, the clothes you wear, and even how your brain works. In a report in a special section on Culture and Psychology in Perspectives on Psychological Science, a journal of the Association for Psychological Science, psychological scientists Denise C. Park from the University of Texas at Dallas and Chih-Mao Huang from the University of Illinois at Urbana-Champaign discuss ways in which brain structure and function may be influenced by culture.

4 Aug 2010

Achievement of tenth milestone triggers EUR 2.5 million payment from Boehringer Ingelheim to Evotec

Evotec AG today announced that its research alliance with Boehringer Ingelheim has reached a milestone, triggering a payment of EUR 2.5 million to Evotec. The milestone reached was the selection of a candidate compound for pre-development studies in an inflammation and immunology programme.

4 Aug 2010

People insensitive to quinine's bitter taste may have varied absorption, metabolization capabilities: Study

Some people find quinine to be bitter while others can drink it like water. Now, scientists from the Monell Center and collaborators report that individual differences in how people experience quinine's bitterness are related to underlying differences in their genes.The findings, published online in the journal Human Molecular Genetics, demonstrate that genetic variation in regions of DNA that encode bitter taste receptors predicts a person's perception of bitterness from quinine.

3 Aug 2010

GG genotype may increase severity of multiple sclerosis symptoms: Study

A new study shows a gene variant may increase the severity of multiple sclerosis (MS) symptoms. The research will be published in the August 3, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.For the study, researchers screened the oligoadenylate synthetase gene in 401 people with MS, 394 people without MS and 178 people receiving the MS treatment beta interferon.

3 Aug 2010

Repligen receives three additional grants to develop HDAC inhibitors for neurodegenerative diseases

Repligen Corporation today announced that the Company has received three additional grants to support its research program to develop HDAC inhibitors for neurodegenerative diseases. Repligen has received $436,000 in research funding to support the ongoing development of histone deacetylase inhibitors for Friedreich's ataxia.

2 Aug 2010

Merck reports strong bottom-line performance in second quarter

Merck & Co., Inc. today announced financial results for the second quarter of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the second quarter of $0.86, which excludes purchase accounting adjustments, merger-related expenses, restructuring costs and the gain on AstraZeneca's asset option exercise. Second-quarter GAAP EPS was $0.24.

2 Aug 2010

FDA lifts hold, allows Geron to proceed with Phase I clinical trial of GRNOPC1 in spinal cord injury

Geron Corporation announced today that the U.S. Food and Drug Administration (FDA) has notified the company that the clinical hold placed on Geron's Investigational New Drug (IND) application has been lifted and the company's Phase I clinical trial of GRNOPC1 in patients with acute spinal cord injury may proceed.

30 Jul 2010

Researchers find new pathway that leads to brain cell death in neurodegenerative disorders

Although their genetic underpinnings differ, Alzheimer's disease, Parkinson's disease and Huntington's disease are all characterized by the untimely death of brain cells. What triggers cell death in the brain? According to a new study published by researchers at Sanford-Burnham Medical Research Institute in the July 30 issue of Molecular Cell, the answer in some cases is the untimely transfer of a gaseous molecule (known as nitric oxide, or NO) from one protein to another.

30 Jul 2010

Research to help people born with 'face blindness'

A specific area in our brains is responsible for processing information about human and animal faces, both how we recognize them and how we interpret facial expressions. Now, Tel Aviv University research is exploring what makes this highly specialized part of the brain unique, a first step to finding practical applications for that information.

29 Jul 2010

MedTera, HealthPrize Technologies partner to help patients self-manage their diseases

MedTera, an integrated marketing solutions company dedicated to improving education, promotion and communications in the healthcare, life sciences and pharmaceutical industries, today announced its formal partnership with HealthPrize Technologies, a web-based software company that motivates people to fill and stay on prescription medications.

29 Jul 2010

Genetic signals determine neurotransmitter use for communication

Cascades of genetic signals determine which neurotransmitter a brain cell will ultimately use to communicate with other cells. Now a pair of reports from biologists at the University of California, San Diego, have shown for the first time that electrical activity in these developing neurons can alter their chemical fate-and change an animal's behavior-by tweaking this genetic program.

29 Jul 2010

FDA Advisory Committee recommends approval of AstraZeneca's ticagrelor for Acute Coronary Syndromes

AstraZeneca today announced that the US Food and Drug Administration Cardiovascular and Renal Drugs Advisory Committee recommended the FDA approve AstraZeneca's investigational drug ticagrelor for the reduction of thrombotic events in patients with Acute Coronary Syndromes.

29 Jul 2010

REM sleep behavior disorder may later lead to neurologic disorders

A new study shows that a sleep disorder may be a sign of dementia or Parkinson's disease up to 50 years before the disorders are diagnosed. The research is published in the July 28, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Jul 2010

NIH grants $14.85 million to complete two floors of NRI at Texas Children's Hospital

Neurological research at Baylor College of Medicine and Texas Children's Hospital is getting a big boost in the form of a $14.85 million grant from the National Institutes of Health to complete two floors of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital.

29 Jul 2010

Increased SIRT1 protein can delay delay aging, extend lifespan

Researchers watched two groups of mice, both nearing the end of a two-day fast. One group was quietly huddled together, but the other group was active and alert. The difference? The second set of mice had been engineered so their brains produced more SIRT1, a protein known to play a role in aging and longevity.

29 Jul 2010

The neck played major role in evolution of human brain: Study

By deciphering the genetics in humans and fish, scientists now believe that the neck - that little body part between your head and shoulders - gave humans so much freedom of movement that it played a surprising and major role in the evolution of the human brain, according to New York University and Cornell University neuroscientists in the online journal Nature Communications (July 27, 2010.)

28 Jul 2010

Experts to discuss treatment options for wounded warriors at USU-HJF Military Medicine Symposium

The USU-HJF Military Medicine Symposium will gather prominent civilian and military researchers and clinicians from across the United States to discuss current research and identify opportunities to collaborate and share information that could speed treatments to wounded warriors. The symposium also will bring together a broad spectrum of participants from military health leadership, federal agencies and private research institutions to philanthropists and charitable foundations, representatives of industry, and policymakers.

28 Jul 2010

Astellas extends non-exclusive license agreement with Regeneron for VelocImmune technology

Regeneron Pharmaceuticals, Inc. and Astellas Pharma Inc. announced that Astellas has extended through 2023 the non-exclusive license agreement that allows Astellas to utilize Regeneron's VelocImmune® technology in its internal research programs to discover fully human monoclonal antibody product candidates.

28 Jul 2010

Neuroscience News and Research

Study links sea sponge genome sequence with first animals and cancer

Detection of Alzheimer's before symptoms occur

Influence of culture on brain structure and function

Achievement of tenth milestone triggers EUR 2.5 million payment from Boehringer Ingelheim to Evotec

People insensitive to quinine's bitter taste may have varied absorption, metabolization capabilities: Study

GG genotype may increase severity of multiple sclerosis symptoms: Study

Repligen receives three additional grants to develop HDAC inhibitors for neurodegenerative diseases

Merck reports strong bottom-line performance in second quarter

FDA lifts hold, allows Geron to proceed with Phase I clinical trial of GRNOPC1 in spinal cord injury

Researchers find new pathway that leads to brain cell death in neurodegenerative disorders

Research to help people born with 'face blindness'

MedTera, HealthPrize Technologies partner to help patients self-manage their diseases

Genetic signals determine neurotransmitter use for communication

FDA Advisory Committee recommends approval of AstraZeneca's ticagrelor for Acute Coronary Syndromes

REM sleep behavior disorder may later lead to neurologic disorders

NIH grants $14.85 million to complete two floors of NRI at Texas Children's Hospital

Increased SIRT1 protein can delay delay aging, extend lifespan

The neck played major role in evolution of human brain: Study

Experts to discuss treatment options for wounded warriors at USU-HJF Military Medicine Symposium

Astellas extends non-exclusive license agreement with Regeneron for VelocImmune technology

Neuroscience - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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