Neuroscience News and Research

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Helsinn Healthcare S.A., Eisai announce signing of licensing agreement

Helsinn Healthcare S.A. and Eisai Inc. today announce the signing of a licensing agreement granting Eisai Inc. commercialization rights for a new product for potential use in the prevention of chemotherapy-induced nausea and vomiting in the United States.

9 Jun 2010

New AAN guideline provides step-by-step process for determining brain death in adults

In an effort to create a uniform and accurate method for determining brain death, the American Academy of Neurology has issued an updated guideline that provides doctors with a step-by-step process for determining brain death in adults. The guideline is published in the June 8, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jun 2010

Self-reported relationship satisfaction among new parents associated with objective total sleep time

First-time parents' relationship satisfaction is related to the amount of sleep they get while caring for an infant, according to a research abstract that will be presented Wednesday, June 9, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

9 Jun 2010

Astellas Pharma acquires OSI Pharmaceuticals for $4.0 billion

Astellas Pharma Inc. announced today that the company has completed its acquisition of OSI Pharmaceuticals, Inc. for $4.0 billion.

9 Jun 2010

Merck's MK-4305 improves overall sleep efficiency in primary insomnia patients

Clinical results from a Phase IIb study showed that MK-4305, Merck's investigational dual orexin receptor antagonist, was significantly more effective than placebo (p<0.005) in improving overall sleep efficiency at night one and at the end of week four in patients with primary insomnia. MK-4305 was generally well-tolerated in the study. Orexins are neuropeptides (chemical messengers) that are released by specialized neurons in the hypothalamus region of the brain and are believed to be an important regulator of the brain's sleep-wake process.

9 Jun 2010

Better understanding of eye movements can help develop strategies for reducing crash risks: Study

More than 16 people are killed and more than 1,300 people are injured each day in crashes involving a distracted driver, a phenomenon that could be reduced with the right application of motion information and appropriate eye movements.

9 Jun 2010

Biogen, Elan launch My MS Health, a web-based PRO research program

Biogen Idec and Elan Corporation, plc, in collaboration with EPI-Q, Inc. and Avatar International, LLC, today announced the launch of My MS Health, a first-of-its-kind, web-based, patient-reported outcomes research program. My MS Health is designed to track and provide instant reports on patient function and quality of life using validated measures over time.

9 Jun 2010

Astellas Pharma completes tender offer for outstanding shares of OSI's common stock

Astellas Pharma Inc. announced today the completion of its tender offer for all outstanding shares of common stock in OSI Pharmaceuticals, Inc..

8 Jun 2010

Vandetanib extends Progression Free Survival in ZETA phase III study for advanced medullary thyroid cancer

Results from ZETA, a phase III study in patients with advanced medullary thyroid cancer (MTC), showed that treatment with the investigational drug vandetanib significantly extended Progression Free Survival (PFS), the primary endpoint of the study, by demonstrating a 54% reduction in the rate of progression compared to placebo.

8 Jun 2010

EKOS receives $2.7M grant to develop product for treatment of ICH

EKOS Corporation announced today that they received a $2.7 million grant from the National Institutes of Health for the development of a product to provide therapy for intracerebral hemorrhagic stroke.

7 Jun 2010

Eisai's eribulin mesylate improves median OS compared with TPC in pre-treated metastatic breast cancer patients

Results of a Phase III study presented today at the American Society of Clinical Oncology (ASCO) Annual Meeting showed that Eisai's eribulin mesylate significantly improved median overall survival (OS) compared with Treatment of Physician's Choice (TPC) in heavily pre-treated metastatic breast cancer patients.

7 Jun 2010

Hunger-signaling hormone ghrelin regulates circulation of cholesterol in brain

Circulation of cholesterol is regulated in the brain by the hunger-signaling hormone ghrelin, researchers say. The finding points to a new potential target for the pharmacologic control of cholesterol levels.

7 Jun 2010

Teva reports encouraging data from study assessing new lower-volume injection of Copaxone at 24th CMSC

Teva Pharmaceutical Industries Ltd. today announced positive results from a study assessing a new lower-volume injection of Copaxone® (glatiramer acetate) containing the currently approved dose in half the injection volume.

5 Jun 2010

Researchers generate the first comprehensive genetic parts list of mouse hypothalamus

A Johns Hopkins and Japanese research team has generated the first comprehensive genetic "parts" list of a mouse hypothalamus, an enigmatic region of the brain — roughly cherry-sized, in humans — that controls hunger, thirst, fatigue, body temperature, wake-sleep cycles and links the central nervous system to control of hormone levels.

4 Jun 2010

Novel brain mechanism promises new and effective anesthetics

A brain mechanism involved in both dreaming and waking from sleep may hold the key to new, more effective anesthetics and stimulants, reported neuroscientists at the University of Arkansas for Medical Sciences (UAMS).

4 Jun 2010

A sense of humor keeps people healthy

A sense of humor helps to keep people healthy and increases their chances of reaching retirement age. But after the age of 70, the health benefits of humor decrease, researchers at the Norwegian University of Science and Technology (NTNU) have found.

4 Jun 2010

Study: Rash adolescent behaviors tied to biological motivations

There are biological motivations behind the stereotypically poor decisions and risky behavior associated with adolescence, new research from a University of Texas at Austin psychologist reveals.

4 Jun 2010

Study confirms Azilect as a selective MAO-B inhibitor

Teva Neuroscience Inc. today announced the publication of a study demonstrating the selectivity of Azilect® (rasagiline tablets) for inhibition of MAO-B (monoamine oxidase-B) at the maximum approved dose of 1 mg/day. The data was published in the Journal of Clinical Pharmacology OnlineFirst on May 5, 2010.

4 Jun 2010

New UNC-Olympus Research Imaging Center opens doors

The University of North Carolina (UNC) at Chapel Hill today opened the doors of a new facility designed to be one of the world's most sophisticated research centers devoted to life science imaging. The new UNC-Olympus Research Imaging Center provides researchers with advanced microscopes and camera equipment, software, consultation and expertise, in an environment intended to encourage the highest levels of scientific inquiry.

From Evident Corporation - Life Sciences 4 Jun 2010

CHOC Children's receives royalty-free research license to certain StemCells' patents

StemCells, Inc. and the Children's Hospital of Orange County ("CHOC Children's") announced today that they have entered into an agreement that provides CHOC Children's with a royalty-free research license to certain of StemCells' patents. This license authorizes CHOC Children's to proliferate, maintain and use human neural stem cells for non-commercial purposes.

4 Jun 2010

Neuroscience News and Research

Helsinn Healthcare S.A., Eisai announce signing of licensing agreement

New AAN guideline provides step-by-step process for determining brain death in adults

Self-reported relationship satisfaction among new parents associated with objective total sleep time

Astellas Pharma acquires OSI Pharmaceuticals for $4.0 billion

Merck's MK-4305 improves overall sleep efficiency in primary insomnia patients

Better understanding of eye movements can help develop strategies for reducing crash risks: Study

Biogen, Elan launch My MS Health, a web-based PRO research program

Astellas Pharma completes tender offer for outstanding shares of OSI's common stock

Vandetanib extends Progression Free Survival in ZETA phase III study for advanced medullary thyroid cancer

EKOS receives $2.7M grant to develop product for treatment of ICH

Eisai's eribulin mesylate improves median OS compared with TPC in pre-treated metastatic breast cancer patients

Hunger-signaling hormone ghrelin regulates circulation of cholesterol in brain

Teva reports encouraging data from study assessing new lower-volume injection of Copaxone at 24th CMSC

Researchers generate the first comprehensive genetic parts list of mouse hypothalamus

Novel brain mechanism promises new and effective anesthetics

A sense of humor keeps people healthy

Study: Rash adolescent behaviors tied to biological motivations

Study confirms Azilect as a selective MAO-B inhibitor

New UNC-Olympus Research Imaging Center opens doors

CHOC Children's receives royalty-free research license to certain StemCells' patents

Neuroscience - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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