Neutrophils News and Research

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Prenatal inflammation may explain why some infants are more prone to neonatal sepsis

Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders.

9 Oct 2018

New inflammatory biomarker correlates with increased thrombosis risk in cancer patients

Cancer patients are known to have an increased risk of thrombosis. As part of the CATS study, MedUni Vienna researchers have now investigated a correlation between an activated immune system in cancer patients and their risk of thrombosis.

26 Sep 2018

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

Non-steroidal anti-inflammatory drugs, or NSAIDs, are commonly used as inflammation blockers worldwide. However, recent clinical data show these painkillers can have serious side effects that create some risk of heart attacks, strokes, and kidney or heart failure.

21 Sep 2018

FDA approves new treatment for people with hairy cell leukemia

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration has approved LUMOXITI (moxetumomab pasudotox-tdfk) for the treatment of adult patients with relapsed or refractory hairy cell leukemia who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

Neutrophil nanosponges provide hope for rheumatoid arthritis

Scientists in San Diego have developed nanosponges coated in neutrophil membranes that can prevent rheumatoid arthritis.

3 Sep 2018

UQ researchers discover new immune defense pathway deployed against bacteria

A new understanding of one of the body’s immune defense mechanisms could lead to the development of novel therapeutic targets for conditions such as cancer and autoimmune diseases, a University of Queensland study has revealed.

31 Aug 2018

Researchers identify neutrophil progenitor in the bone marrow of mice and humans

Neutrophils-;short-lived, highly mobile and versatile-;outnumber all other immune cells circulating through the blood stream.

29 Aug 2018

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

XBiotech Inc. announced today the publication of findings that point toward a white blood cell-derived interleukin-1 alpha (IL-1⍺) as a cause of blood clots that could lead to heart attacks or strokes.

28 Aug 2018

Study provides new insights into how the human immune system protects against Ebola infections

Two types of human antibodies that target different parts of the Ebola virus synergize their antiviral effects by inhibiting different steps of infection, according to a study published August 23 in the open-access journal PLOS Pathogens by Philipp Ilinykh and colleagues from the University of Texas Medical Branch, Vanderbilt University, and Ragon Institute.

24 Aug 2018

Natural enzyme found in the human lungs can biodegrade graphene

Graphene Flagship partners discovered that a natural human enzyme can biodegrade graphene. These findings could have great implications in the development of graphene-based biomedical devices.

23 Aug 2018

Researchers use 3D printer to create microfluidic probe for studying cancer cells

NYU Abu Dhabi Assistant Professor of Mechanical and Biomedical Engineering Mohammad Qasaimeh, and NYU Abu Dhabi Global PhD Fellow in Engineering and first author of the research Ayoola T. Brimmo, along with other researchers, used a 3D printer to create a functional, integrated, and inexpensive microfluidic probe to study cancer cells and other living organisms in a Petri dish.

9 Aug 2018

Study provides new insights into how asthma develops and progresses

Of the more than 24 million people in the U.S. who have asthma, 10 percent have severe asthma - a form of the disease that does not respond to treatment.

3 Aug 2018

Experimental compound reverses hair loss, skin inflammation related to fatty diet, mice study shows

In a series of experiments with mice, Johns Hopkins investigators have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol.

30 Jul 2018

Immune cells may actually disrupt moisturizing glands and cause dry eye disease

Immune cells that normally rush in to protect the eyes from infection might actually be disrupting moisturizing glands and causing dry eye, a disease that afflicts more than 30 million people in the United States.

26 Jul 2018

Pfizer announces FDA approval of biosimilar to Neupogen

Pfizer Inc. today announced that the United States Food and Drug Administration has approved NIVESTYM (filgrastim-aafi), a biosimilar to Neupogen (filgrastim), for all eligible indications of the reference product.

23 Jul 2018

SATB1 protein important for maintaining pluripotency of hematopoietic stem cells

Osaka University scientists demonstrate that SATB1 is important for maintaining pluripotency of hematopoietic stem cells

4 Jul 2018

Seeing the Unexpected: Regulatory T Cells and Basophils

Dr. Jagadeesh Bayry from INSERM discusses his recent research in the field of immunology, and how T regulatory cells activate, rather than suppress, basophils.

4 Jul 2018

Preventive treatment for recurrent pregnancy loss proved ineffective in large study

An immune response to pregnancy (in which the uterus rejects the embryo or fetus) is said to explain a large number of otherwise "unexplained" miscarriages.

3 Jul 2018

Antioxidant-enriched vitamin may decrease exacerbations in cystic fibrosis patients

An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis(CF), according to new research published online in April in the American Journal of Respiratory and Critical Care Medicine.

2 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.