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Discovery of key molecular target in age-related macular degeneration

A team of researchers led by Dr. Jayakrishna Ambati at the University of Kentucky has discovered a biological marker for neovascular age-related macular degeneration (AMD), the leading cause of blindness in older adults.

15 Jun 2009

Discovery of new angiogenesis protein - possible cancer drug target

To grow and spread, tumors need new blood vessels, a process called angiogenesis. One growth factor that causes angiogenesis has been identified - vascular endothelial growth factor or VEGF - and drugs to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long term. Thus new growth factors need to be identified to aid in developing the next generation of angiogenesis inhibitors.

9 Jun 2009

Noninvasive screening test detects digestive cancers in multiple organs

Mayo Clinic researchers have demonstrated that a noninvasive screening test can detect not only colorectal cancer but also the common cancers above the colon -- including pancreas, stomach, biliary and esophageal cancers. This is one of more than 100 Mayo Clinic studies being presented at Digestive Disease Week 2009 in Chicago, May 30 - June 4.

2 Jun 2009

Language use decreases in young children and caregivers when TV is on

In a new study, young children and their adult caregivers uttered fewer vocalizations, used fewer words and engaged in fewer conversations when in the presence of audible television.

1 Jun 2009

Intradigm issued RNA interference (RNAi) patent covering potent siRNA sequence

Intradigm Corporation has announced the issuance of United States patent 7,534,878, titled "Composition and Methods of RNAi Therapeutics for Treatment of Cancer and Other Neovascularization Diseases."

19 May 2009

Biovail acquires worldwide rights to Tetrabenazine

Biovail Corporation today announced a wholly owned subsidiary has entered into a definitive agreement to acquire worldwide development and commercialization rights to the entire portfolio of tetrabenazine products, including Xenazine/Nitoman (tetrabenazine tablets), and the associated intellectual property rights held by Cambridge Laboratories (Ireland) Ltd and its affiliates.

18 May 2009

FDA clears new treatment for facial wrinkles

Ellman International, Inc. announced today that the Food and Drug Administration (FDA) has granted clearance to Pelleve, a skin tightening system for the non-ablative treatment of mild to moderate facial wrinkles and rhytids for skin phototypes I-IV.

18 May 2009

Nanodiamonds for drug delivery

A research team at Northwestern University has demonstrated a tool that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells.

18 May 2009

Endorphins, personality, and inheritance

A new article published in Elsevier's journal Bioscience Hypotheses suggests that our feelings in our lifetime can affect our children.

14 May 2009

From implantable devices to electric vehicles, UB Professor focuses on power sources

A University at Buffalo professor who has garnered more than 140 patents for power sources for tiny biomedical devices now is working to develop batteries that could power much larger devices, such as electric vehicles.

13 May 2009

Scientists develop whole-genome sequencing approach to mapping mutations in fruit flies

The Stowers Institute's Hawley Lab and Molecular Biology Facility have developed a "whole-genome sequencing approach" to mapping mutations in fruit flies.

5 May 2009

Call for mothers to address bone health with daughters

Of all the gifts that generations of women have passed on to their loved ones, one of the most important is the gift of knowledge about health - especially information about bone health and osteoporosis.

3 May 2009

Collagen bioscaffolds used to treat diabetic ulcers, save limbs

San Diego surgeons report that they have been successfully utilizing a collagen bioscaffold material developed by Irvine-based Pegasus Biologics, Inc. to complement soft tissue repair and regeneration among high risk wound patients.

22 Apr 2009

DNA of uncultured organisms sequenced using novel single cell genome sequencing approach

Scientists from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) and the Bigelow Laboratory for Ocean Sciences have assembled high quality, contamination-free draft genomes of uncultured biodegrading microorganisms using a novel single cell genome sequencing approach.

22 Apr 2009

Study finds link between a mother's height and the health of her children

Researchers at the Harvard School of Public Health (HSPH) have found a link between a mother's height and the health of her children in a study using national data from India.

22 Apr 2009

Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies

Peregrine Pharmaceuticals, Inc. has reported that two preclinical studies presented during the AACR 100th Annual Meeting 2009 provided further confirmation of the immunomodulatory mechanisms contributing to the anti-tumor activity of its phosphatidylserine (PS) targeting antibodies.

22 Apr 2009

The DNA proteome

The human genome complete sequencing project in 2003 revealed the enormous instruction manual necessary to define a human being.

22 Apr 2009

Potential genetic cause of congenital defect colonic atresia

In a finding that helps resolve a long-standing question in developmental biology, Klaus H. Kaestner, PhD, Professor of Genetics, and colleagues report in the journal Developmental Cell this week about how the mammalian gut forms. Mice were genetically engineered to lack the protein Cdx2 in the cells that normally go on to form the stomach and intestine.

22 Apr 2009

New clues to how stem cells form

An Emory University study shows some of the first direct evidence of a process required for epigenetic reprogramming between generations – a finding that could shed more light on the mechanisms of fertilization, stem-cell formation and cloning.

16 Apr 2009