Next generation sequencing NGS News and Research

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Life Technologies adds SOLiD PI System to sequencing solutions portfolio

Life Technologies Corporation today announced plans for the Applied Biosystems SOLiD™ PI System, a new highly accurate, flexible and easy-to-use genomic analysis platform that will bring next-generation sequencing within the grasp of all life science research laboratories worldwide. Early customer adoption of the SOLiD PI System is expected to begin in the second half of 2010.

24 Feb 2010

New England Biolabs adds NEBNext DNA Sample Prep Master Mix Set 3 for use with Life Technologies' SOLiD 3 System

New England Biolabs has expanded its line of reagents for sample preparation to include NEBNext™ DNA Sample Prep Master Mix Set 3, which has been validated for use with the SOLiD™ 3 System from Life Technologies. NEBNext reagents are a series of highly pure reagents that facilitate sample preparation for downstream applications, such as next generation sequencing. All reagents undergo stringent quality controls and functional validation, ensuring maximum yield, convenience and value.

From New England Biolabs 24 Feb 2010

Caliper Life Sciences forms SAB to develop additional solutions for next generation sequencing workflows

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today announced the formation of a scientific advisory board to guide its efforts in automated sample preparation for next generation and third generation sequencing platforms. Caliper worked closely with leading genome centers to develop the LabChip® XT, which was announced today, and is now expanding its efforts to develop additional solutions for next generation sequencing workflows.

22 Feb 2010

$Caliper Life Sciences introduces automated nucleic acid fractionation instrument, LabChip XT$

Caliper Life Sciences introduces automated nucleic acid fractionation instrument, LabChip XT

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today introduced the LabChip XT, an automated nucleic acid fractionation instrument.

19 Feb 2010

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

Life Technologies Corporation today announced the publication of two key scientific papers that highlight the utility of next-generation sequencing instruments in better understanding disease and the genetic differences that cause diversity within and between human populations. The Applied Biosystems SOLiD™ System was used in both of these research studies.

19 Feb 2010

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Scientists at the Johns Hopkins Kimmel Cancer Center have used data from the whole genome sequencing of cancer patients to develop individualized blood tests they believe can help physicians tailor patients' treatments. The genome-based blood tests, believed to be the first of their kind, may be used to monitor tumor levels after therapy and determine cancer recurrence.

19 Feb 2010

RainDance Technologies enters into strategic agreement with Applied Biosystems

RainDance Technologies, Inc., a leading provider of innovative microdroplet-based solutions for human health and disease research, and Applied Biosystems, part of Life Technologies Corporation, announced today they have entered into a strategic agreement to co-market the first solution that combines microdroplet PCR-based sequence enrichment with next-generation sequencing.

19 Feb 2010

febit introduces new HybSelector instrument for next-generation resequencing solutions

febit today announced the launch of its HybSelector, a new instrument for high throughput targeted resequencing, at the 11th annual Advances in Genome Biology and Technology (AGBT) meeting on February 24-27, 2010, in Marco Island, Florida.

18 Feb 2010

Fluidigm releases amplicon tagging protocol for Illumina GA II next-generation sequencer

Fluidigm Corporation today announced the release of its amplicon tagging protocol for the Illumina GA II next-generation sequencer. The 48.48 Access Array integrated fluidic circuit (IFC) allows Illumina GA II users to automatically prepare sequencing-ready libraries from 48 individual samples at a time, for as little as $7 (U.S.) per sample.

10 Feb 2010

New England Biolabs to supply Wellcome Trust Sanger Institute next-generation sequencing library construction reagents

As an important supplier to the Wellcome Trust Sanger Institute, New England Biolabs is pleased to announce that the Sanger Institute will use New England Biolabs as one of its suppliers for next-generation sequencing library construction reagents.

From New England Biolabs 5 Feb 2010

Rubicon Genomics reaches agreement with ZyGEM to market its PicoPlex single-cell amplification kits

Rubicon Genomics, Inc., a developer of pre-analytical amplification products that enable more comprehensive genetic analysis of clinical and research samples, announced today that it has reached agreement with ZyGEM to non-exclusively market Rubicon's PicoPlex™ single-cell amplification kits in Australia and New Zealand.

30 Jan 2010

Life Technologies reports fourth-quarter and fiscal year results ended December 31, 2009

Life Technologies Corporation today announced results for its fourth quarter and full year ending December 31, 2009. Non-GAAP revenue for the fourth quarter was $874 million, resulting in full year non-GAAP revenues of $3.30 billion, an increase of 5 percent over the $3.14 billion reported for 2008, as if Invitrogen and Applied Biosystems had been combined.

From Danaher 28 Jan 2010

New insight into reprogramming of cells

A discovery by Babraham scientists brings new insight into how cells are reprogrammed and a greater understanding of how the environment, or factors like nutritional signals, can interact with our genes to affect health. As an embryo develops, cells acquire a particular fate, for example becoming a nerve or skin cell. The findings, reported online in the journal Nature, pinpoint a protein called AID as being important for complete cellular reprogramming in mammals.

28 Jan 2010

IntegraGen now offers Fluidigm's IFC technology to French researchers

Fluidigm, the inventor of integrated fluidic circuits (IFCs), has joined with IntegraGen SA, one of France’s leading providers of genetic research testing services, to bring IFC technology to French researchers. IntegraGen will offer premium class services to its customers using the Fluidigm BioMark™ System for Genetic Analysis and the Access Array™ sample preparation system for next-generation sequencing. IntegraGen’s lab will also be a demonstration site for researchers investigating Fluidigm’s technology.

25 Jan 2010

Affomix, City of Hope collaborate in exploring next generation sequencing using digital proteomics

Affomix Corporation, a pioneer in high performance antibody technology, announced today a collaboration with City of Hope focused on establishing the clinical utility of “digital proteomics” with next generation sequencers. One of the nation’s top cancer research and treatment centers, City of Hope is a leading provider of molecular diagnostic testing services and an innovator in clinical genetics research.

19 Jan 2010

Joubert Syndrome - an inherited neurological disease found among Ashkenazi Jews

Two scientists from Cold Spring Harbor Laboratory (CSHL) are part of an international team that has discovered a genetic mutation that causes Joubert Syndrome. JBTS, as it is commonly called, is a devastating inherited neurological disease that is very rare in the general population but found relatively more often among Ashkenazi Jews.

18 Jan 2010

Kapa Biosystems signs non-exclusive North American distribution agreement with VWR International

Kapa Biosystems and VWR International, LLC announced today that they have entered into a non-exclusive North American distribution agreement for Kapa Biosystems' line of next-generation PCR reagents.

13 Jan 2010

Agilent Technologies, Covaris sign co-marketing agreement to streamline next-generation sequencing experiments

Agilent Technologies, Inc. (NYSE:A) and Covaris Inc. today announced a co-marketing agreement in which Covaris S2 DNA shearing technology will be marketed with the Agilent SureSelect Target Enrichment System to streamline next-generation sequencing experiments.

6 Jan 2010

Scientists use DNA sequence to characterize genome rearrangement in breast cancer samples

The first detailed search of breast cancer genomes to uncover genomic rearrangements is published today. The team characterised the ways in which the human genome is broken and put back together in 24 cases of breast cancer.

23 Dec 2009

Next-generation DNA sequencing demonstrates potential in identifying mutations in SCLC

Applied Biosystems, part of Life Technologies Corporation, today announced the publication of a paper in the journal Nature that demonstrates the power of next-generation DNA sequencing used to identify DNA mutations in a small cell lung cancer (SCLC) line and identify the mutational burden associated with tobacco smoking.

17 Dec 2009

Next generation sequencing NGS News and Research

Life Technologies adds SOLiD PI System to sequencing solutions portfolio

New England Biolabs adds NEBNext DNA Sample Prep Master Mix Set 3 for use with Life Technologies' SOLiD 3 System

Caliper Life Sciences forms SAB to develop additional solutions for next generation sequencing workflows

Caliper Life Sciences introduces automated nucleic acid fractionation instrument, LabChip XT

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

RainDance Technologies enters into strategic agreement with Applied Biosystems

febit introduces new HybSelector instrument for next-generation resequencing solutions

Fluidigm releases amplicon tagging protocol for Illumina GA II next-generation sequencer

New England Biolabs to supply Wellcome Trust Sanger Institute next-generation sequencing library construction reagents

Rubicon Genomics reaches agreement with ZyGEM to market its PicoPlex single-cell amplification kits

Life Technologies reports fourth-quarter and fiscal year results ended December 31, 2009

New insight into reprogramming of cells

IntegraGen now offers Fluidigm's IFC technology to French researchers

Affomix, City of Hope collaborate in exploring next generation sequencing using digital proteomics

Joubert Syndrome - an inherited neurological disease found among Ashkenazi Jews

Kapa Biosystems signs non-exclusive North American distribution agreement with VWR International

Agilent Technologies, Covaris sign co-marketing agreement to streamline next-generation sequencing experiments

Scientists use DNA sequence to characterize genome rearrangement in breast cancer samples

Next-generation DNA sequencing demonstrates potential in identifying mutations in SCLC

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