Nitric Oxide News and Research

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Inhaled nitric oxide safe for very premature infants

A nationwide study led by researchers at UCSF provides evidence that inhaled nitric oxide is safe and effective for the prevention of the most common type of long-term lung disease of very premature infants.

7 Aug 2007

Ibuprofen improves cognitive function in rats induced with chronic liver failure

Cognitive impairment is one of the neurological effects in patients with hepatic encephalopathy (abnormal brain function due to severe liver disease).

2 Aug 2007

Preconditioning protects brain from stroke

Challenging brain tissue with a small noxious stimulus beforehand gives it a resilience that can lessen damage to blood vessels during a stroke, report researchers at Weill Cornell Medical College in New York City.

18 Jul 2007

Warwick first new medical school to join MRC strategic partnership

Warwick Medical School has become the first new medical school to join a strategic partnership with the Medical Research Council (MRC).

16 Jul 2007

Myeloperoxidase offers clues to heart attack in seemingly healthy people

We've all wondered how a seemingly healthy person can actually be at high risk for heart disease or a heart attack.

4 Jul 2007

Myeloperoxidase protein provides clues to heart attacks in healthy people

We've all wondered how a seemingly healthy person can actually be at high risk for heart disease or a heart attack.

4 Jul 2007

Research explains why those with obstructive sleep apnea are at higher risk for cardiovascular disease

Researchers have found that patients with obstructive sleep apnea (OSA) have higher levels of a type of dead cells (apoptotic cells) from the lining (endothelium) of their blood vessels circulating in their bloodstream than people who do not have OSA.

3 Jun 2007

Pycnogenol natural pine bark extract reduces heart failure

A study to be published in an upcoming edition of the journal of Cardiovascular Toxicology reveals Pycnogenol natural pine bark extract from the French maritime pine tree, helps prevent damage that high blood pressure causes to the heart.

17 May 2007

Premature birth rate in U.S. linked to increased use of pesticides and nitrates

The growing premature birth rate in the United States appears to be strongly associated with increased use of pesticides and nitrates, according to work conducted by Paul Winchester, M.D., professor of clinical pediatrics at the Indiana University School of Medicine.

8 May 2007

Premature births may be linked to seasonal levels of pesticides and nitrates in surface water

7 May 2007

Nitric oxide may be the key to why specific drugs for heart failure or asthma lose their effectiveness over time

A naturally occurring molecule in the body appears to control whether certain medications, such as beta adrenergic receptor agonists used in acute heart failure or in inhalers for asthma, lose their effectiveness over time.

4 May 2007

Cause of gender differences in high blood pressure and related kidney disease

While men and women both get high blood pressure and related kidney disease, the path to get there is shorter, steeper and just different for men, researchers say.

4 May 2007

BioMarin starts phase 2a study of 6R-BH4 in sickle cell disease

BioMarin Pharmaceutical has announced that the first patient has initiated treatment in the Phase 2a clinical study of 6R-BH4 (sapropterin dihydrochloride) for the treatment of sickle cell disease (SCD).

4 May 2007

Simvastatin may help sufferers with Alzheimer's

Treatment with Simvastatin, one of the statin drugs widely used for lowering cholesterol in humans, significantly improved spatial memory - how to navigate a water maze - in mice genetically bred to have an Alzheimer's like disease.

1 May 2007

Taming chronic cough

Chronic cough – often causing much discomfort, frustration, irritability and sleep disturbances in 10 percent to 20 percent of adults – is one of the leading reasons for consultation with a physician according to a report published this month in Annals of Allergy, Asthma & Immunology , the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

21 Apr 2007

Pollen which is allergenic releases much greater amounts of nitric oxide and nitrite than a non-allergenic pollen

Hayfever is a major irritation for up to 20% of the population in most economically developed countries.

4 Apr 2007

Tilarginine does not reduce risk of death after heart attack

The medication tilarginine, a drug that was believed could be beneficial for patients who develop cardiogenic shock (low blood pressure due to impaired cardiac function) after a heart attack, did not reduce the risk of death up to six months after a heart attack, according to a JAMA study published online March 26.

2 Apr 2007

Fats in our stomach may reduce the protective effects of antioxidants

Scientists at the University of Glasgow found that in the presence of lipid the ability of antioxidants, such as ascorbic acid (the active component of vitamin C), to protect against the generation of potential cancer-forming compounds in the stomach is less than when no lipids are present.

2 Apr 2007

C-Reactive protein plays a direct role in the onset of hypertension

We have discovered that C-Reactive Protein (CRP) is not merely a marker of the risk of hypertension, it actually induces hypertension.

19 Feb 2007

New understanding of blood pressure gene could lead to new treatments

Research by scientists at UCL (University College London) has clearly demonstrated for the first time the structure and function of a gene crucial to the regulation of blood pressure. The discovery could be important in the search for new treatments for illnesses such as heart disease, the UK's biggest killer.

5 Feb 2007