Non Steroidal Anti Inflammatory Drug (NSAIDS) News and Research

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Role of acetaminophen in acute myocardial infarction

Acetaminophen is safe to use as a pain reliever and fever reducer after a heart attack, but it does not protect the heart muscle, a new study using sheep and rabbits concluded.

16 May 2006

Drug combo significantly more effective in reducing dyspepsia in arthritis patients

UCLA/VA researchers found that for arthritis patients, taking a combination of two drugs may be most effective in protecting against stomach upset called dyspepsia, which is a side effect of common pain medications.

3 May 2006

Researchers clarify the mechanism by which drugs like Celebrex and Vioxx cause heart problems

Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models.

18 Apr 2006

Nimesulide fights breast cancer by targeting key enzyme

A pain-killing medication appears to halt the production of an enzyme that is key to a common form of breast cancer, a new study using tissue cultures suggests.

16 Apr 2006

Inflammation cuts both ways

Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder.

6 Apr 2006

Regular use of COX-2 inhibitors may reduce the risk of breast cancer

Results from a new, five-year study show that regular use of popular prescription pain relievers may reduce the risk of breast cancer by up to 71 percent and may offer similar benefit in the prevention of prostate, colon and lung cancers.

4 Apr 2006

Treatment reduces gastric ulcers in at-risk patients using long-term NSAIDS

Esomeprazole magnesium can reduce the incidence of gastric (stomach) ulcers in patients at risk of developing gastric ulcers and who regularly take either non-selective nonsteroidal anti-inflammatory drugs (NSAIDs) or COX-2-selective NSAIDs

30 Mar 2006

Medicinal properties in mahogany bark may hold colon cancer cure

U of So. Carolina cancer researcher Dr. Michael Wargovich is studying whether medicinal properties in the bark of mahogany trees may hold clues to understanding colon cancer.

27 Mar 2006

Celebrex safe for osteoarthritis

According to a study by Stanford University School of Medicine, Celebrex causes fewer gastrointestinal complications than traditional nonsteroidal anti-inflammatory painkillers or NSAIDs in osteoarthritis patients and does not increase the risk of heart attacks.

1 Mar 2006

Link between rheumatoid arthritis and cancer examined

Rheumatoid arthritis is an inflammatory disease of the immune system and is thought to be linked to an increased risk of cancers of the lymphatic system.

28 Feb 2006

Study associates chronic, severe inflammation with increased lymphoma risk among RA patients

An inflammatory disease of the immune system, rheumatoid arthritis (RA) is associated with increased occurrence of lymphoma--or cancers of the lymphatic system, which plays an integral role in the body's ability to fight infection.

27 Feb 2006

Drugs formerly contraindicated for inflammatory bowel disease prove beneficial for pain relief

According to two studies published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, prescription painkillers are effective in easing the pain of patients with dormant inflammatory bowel disease (IBD) and are not likely to cause symptom flare-ups in IBD patients in remissions

12 Feb 2006

Regular use of COX-2 inhibitors reduces breast cancer risk

A case-control study published today in the open access journal BMC Cancer observed that daily use of selective COX-2 inhibitors, including celecoxib (Celebrex) and rofecoxib (Vioxx), was associated with a 71% reduction in the risk of breast cancer.

2 Feb 2006

Celebrex and Vioxx reduce the risk of breast cancer

According to a new study, the regular use of drugs such as Celebrex and Vioxx significantly reduces the risk of breast cancer.

30 Jan 2006

Vioxx may still be the best option for treating some forms of arthritis

Scientists believe that despite the current concerns around anti-inflammatory drugs like Vioxx, they may still be the best option for treating some forms of arthritis.

18 Jan 2006

Pfizer to fund independent trial on Celebrex and heart risks

Drug company Pfizer Inc., the maker of Celebrex, will pay for an international study of 20,000 people.

14 Dec 2005

COX-2 inhibitors may not be as safe as originally thought

There is no evidence to back up claims that the new generation of anti-inflammatory drugs (COX-2 inhibitors) are less harmful to the stomach lining than many traditional anti-inflammatory drugs, concludes a study in the British Medical Journal.

7 Dec 2005

Short-term use of painkiller drugs does not increase the risk of heart attack

Short-term use of painkiller drugs in the same family as ibuprofen does not increase the risk of having a heart attack.

7 Dec 2005

Warning labels on high-risk drugs ignored by doctors

In a survey of approximately 930,000 ambulatory care patients, researchers from the Department of Ambulatory Care and Prevention (of Harvard Medical School and Harvard Pilgrim Health Care) and colleagues found that 42 percent received prescriptions for drugs with Black Box Warnings (BBW), the Food and Drug Administration's strongest label for high-risk medication.

21 Nov 2005

Taking either COX-2 inhibitors or NSAIDs after a heart attack increases the risk of death

In recent years, evidence has shown that patients treated with selective cyclo-oxygenase-2 (COX-2) inhibitors are at increased risk of heart attack and death. COX-2 inhibitors are used primarily to treat pain and arthritis in patients at risk of gastrointestinal bleeding.

13 Nov 2005