Nucleotides News and Research

RSS

New NGS technique offers quick, accurate diagnosis of sepsis

A report in the Journal of Molecular Diagnostics, published by Elsevier, describes a new technique that uses real-time next-generation sequencing to analyze tiny amounts of microbial cell-free DNA in the plasma of patients with sepsis, offering the possibility of accurate diagnosis of sepsis-causing agents within a few hours of drawing blood.

5 Mar 2020

A new, promising method for developing drugs that target, block macropinocytosis

With drug resistance a major challenge in the fight against cancer, a discovery by University of California, Irvine biologists could offer new approaches to overcoming the obstacle.

3 Mar 2020

New approach to identify pathogenic genes in virus strains at a glance

When new viruses or bacteria spread to humans, it is essential to clarify their special characteristics as quickly as possible.

27 Feb 2020

Scientists think they've found the earliest interbreeding event

A new study published in the journal Science Advances in February 2020 reports that it has found the earliest interbreeding event between different human populations ever, where the "super-archaics" of Eurasia interbred with another group known as the Neanderthal-Denisovan population long ago.

20 Feb 2020

Supersensitive nanomaterials hold promise for DNA analysis and next-generation drugs

In 1900, German physician Paul Ehrlich came up with the notion of a "magic bullet." The basic idea is to inject a patient with smart particles capable of finding, recognizing, and treating a disease. Medicine has pursued the magic bullet ever since.

19 Feb 2020

Researchers identify control of a mitochondrial protective mechanism

Mitochondria are known as the "powerhouses" of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation.

12 Feb 2020

Researchers discover fundamental mechanism that regulates gene activity in cells

Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a fundamental mechanism that regulates gene activity in cells.

4 Feb 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020

Scientists discover a new way to combine coding languages into single "bilingual" molecule

The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes underlying all of life.

10 Jan 2020

Scientists create 3D images of unique RNA molecule critical for stem cell programming

Scientists at Los Alamos and international partners have created the first 3-D images of a special type of RNA molecule that is critical for stem cell programming and known as the "dark matter" of the genome.

10 Jan 2020

Scientists find way to combine two main coding languages into single 'bilingual' molecule

9 Jan 2020

Novel HIV vaccine shows promise

There are millions living with HIV and researchers have been working towards making a successful vaccine against the deadly infection for the past 35 years with no success. Now a new blueprint is being developed to prevent the infection.

15 Dec 2019

Researchers find many psychiatric disorders share the same gene variants

An international team of researchers has found that many psychiatric disorders share a common and specific set of gene variants.

13 Dec 2019

New approach to broadly acting, highly effective HIV vaccine

Researchers have reported a major advance in the creation of a successful HIV vaccine that is not produced by the host animal.

9 Dec 2019

New antiviral drug drives treatment resistance in influenza viruses

On January 31, 2019, an 11-year old boy in Japan went to a medical clinic with a fever. The providers there diagnosed him with influenza, a strain called H3N2, and sent him home with a new medication called baloxavir.

25 Nov 2019

New flu drug makes influenza viruses develop resistance

Researchers have discovered a mutation in strains of influenza treated with a drug that makes the virus resistant to treatment.

25 Nov 2019

Impaired gene expression may influence aging via altered cellular metabolism

Throughout history, humans have been obsessed with finding a way to prevent aging and prolong life. Although the mechanisms have long eluded us, modern science is revealing more and more about the aging process. Now, researchers from Japan have uncovered new information about the genetic processes that may trigger age-related disorders, including low energy production and low cellular growth.

20 Nov 2019

Measuring development in young children: the DNA clock

Scientists have come up with a new discovery that could transform our understanding of how childhood growth and development are measured – the DNA clock. The study, published in the Proceedings of the National Academy of Science, is the first paper to...

16 Oct 2019

Study presents a new view on how mitochondrial dysfunction may contribute to aging

Disturbances in the function of mitochondrial DNA can accelerate the aging process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism.

8 Oct 2019

Video images offer real-time view into the kinetics of viral assembly

For the first time, researchers have captured images of the formation of individual viruses, offering a real-time view into the kinetics of viral assembly. The research provides new insights into how to fight viruses and engineer self-assembling particles.

4 Oct 2019