Organoids News and Research

RSS

Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Scientists demonstrate potential of imaging technique based on physical properties of tumors

A team of physicists at the Institut Lumière Matière, in collaboration with the Cancer Research Center of Lyon, has demonstrated the potential, for oncology, of an imaging technique based only on the physical properties of tumors.

8 Jan 2019

Salk researchers reveal clues into early development of ASD

Autism spectrum disorder is a relatively common developmental disorder of communication and behavior that affects about 1 in 59 children in the US, according to the Centers for Disease Control and Prevention. Despite its prevalence, it is still unclear what causes the disease and what are the best ways to treat it.

7 Jan 2019

Scientists create patient-specific model to identify most effective treatment for appendix cancer

Scientists at the Wake Forest Institute for Regenerative Medicine have recently developed a process that may change the way cancer of the appendix is treated in the future.

17 Dec 2018

Research pinpoints two proteins involved in creation of stem cells

Mammalian embryos are unlike those of any other organism as they must grow within the mother's body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ. By contrast, mammalian embryos must first choose between forming the placenta or creating the baby.

11 Dec 2018

Scientists create mini-placenta's to study early stages of pregnancy

Researchers at the University of Cambridge have used organoid culture techniques to create a cellular model of the early stages of the placenta.

29 Nov 2018

“Placental organoids” could be the future of pregnancy and conception research say researchers

Researchers have successfully managed to develop “mini placentas” or placenta organoids in the laboratories that could transform research of pregnancy, conception, stillbirth, miscarriages and pregnancy diseases and disorders.

29 Nov 2018

Two types of cellular asymmetry govern shaping of cells into sheets and tubes

Scientists have developed a mathematical model showing that two types of cellular asymmetry, or 'polarity', govern the shaping of cells into sheets and tubes, according to an article in eLife.

28 Nov 2018

Brain and muscle cells found within kidney organoids

Researchers have discovered the presence of rogue brain and muscle cells inside kidney organoids and used artificial intelligence to remove them.

15 Nov 2018

The Human Mini Heart-in-a-Jar That Could One Day Replace Animal Testing

An interview with Dr. Kevin Costa, discussing the miniaturized heart-in-a-jar model developed by Novoheart, and its applications in personalized medicine.

12 Nov 2018

Multidisciplinaryresearch teams selected to study age-related brain disorders

Could our blood hold the molecular secrets to a fountain of youth, preventing age-related brain disorders? Are brain aging and Alzheimer's disease caused by a failure of interconnected systems in our bodies, triggering a domino-like cascade of disease? Can targeting the red blood cells and blood vessels jointly keep our brains healthy and prevent dementia?

12 Nov 2018

Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline

A team of Salk Institute researchers led by President Rusty Gage has been awarded $19.2 million over eight years by the American Heart Association-Allen Initiative in Brain Health and Cognitive Impairment to investigate mechanisms underlying Alzheimer's disease and aging-related cognitive decline and uncover new therapies.

12 Nov 2018

Scientists identify 'skeleton key' for congenital kidney disease research

Scientists in Japan have found a 'skeleton key' for congenital kidney disease research. Using iPS cells generated from the skin cells of a patient with a nephrin mutation, Kumamoto University scientists have successfully developed kidney tissue that exhibits the early stages of congenital kidney disease.

31 Oct 2018

Groundbreaking Khíron chip enables fast, accurate intra-tissue measurement

A new gold standard for electrical measurement in the emerging in vitro world of three dimensional models. That's what Swiss medtech 3Brain has established by partnering with CSEM.

30 Oct 2018

Lab-created mini retinas allow researchers to understand retinal ganglion cell development

IUPUI biologists are growing 'mini retinas' in the lab from stem cells to mimic the growth of the human retina. The researchers hope to use the research to restore sight when critical connections between the eye and the brain are damaged.

25 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Study to explore bioethics of brain organoids

Research scientists around the world are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids.

16 Oct 2018

Lab grown retinal cells provide clues to color blindness treatment

Researchers have grown human retinal cells in the laboratories and thus attempted to understand the basis of color vision and its development in humans. The results showed that certain hormones are essential for the development of color vision in humans and were published in the latest issue of the journal Science.

11 Oct 2018

Researchers develop organoid that functions as real salivary gland

Researchers have successfully used induced pluripotent stem cells to grow a 3D salivary gland tissue that produces saliva when implanted in mice.

11 Oct 2018

Scientists succeed in growing functional salivary gland

A research group led by scientists from Showa University and the RIKEN Center for Biosystems Dynamics Research in Japan have, for the first time, succeeded in growing three-dimensional salivary gland tissue that, when implanted into mice, produced saliva like normal glands.

11 Oct 2018

Researchers aim to create more authentic organoids for drug testing, transplantation

Human embryos start as a tiny mass of cells that are all the same. The first step in growing from a homogenous ball of cells into a complex individual with distinct organs and tissues is for the cells to divide into distinct populations.

10 Oct 2018