Orthopedics News and Research

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Congenital anomaly prevalence should spark ART policy change

Assisted reproductive technology may be associated with the increased proportion of multiple birth infants affected by congenital abnormalities since the 1980s, European research suggests.

12 Feb 2013

Lipid associated variant linked to aortic stenosis, valve disorders

People who carry a lipoprotein(a) gene variant are at increased risk for aortic valve calcification and aortic stenosis, suggest study findings.

11 Feb 2013

Taro, Sun Pharma mutually agree to terminate merger agreement

Taro Pharmaceutical Industries Ltd. and Sun Pharmaceutical Industries Ltd. announced today that they have mutually agreed to terminate their merger agreement, announced in August 2012, pursuant to which all shareholders of Taro would have received a cash payment of $39.50 per share upon the closing of the merger.

10 Feb 2013

Patients with low-grade ACL injuries from skiing can heal without surgery

Roughly a quarter of recreational skiers who tear their anterior cruciate ligament (ACL) while hitting the slopes can be successfully treated without surgery, according to a new study.

7 Feb 2013

SOS Children's Villages launches new Nursing and Midwife Scholarship program in Ethiopia

SOS Children's Villages, a global organization dedicated to providing family-based care for orphaned and abandoned children, today announced the launch of a brand new Nursing and Midwife Scholarship program in Ethiopia.

6 Feb 2013

Tumor suppressor mutant may predict poor outcome in breast cancer

An oncogenic variant of the Krüppel-like family 6 tumor suppressor gene appears to play a role in driving breast cancer metastasis and may be a prognostic marker for poor patient outcome, report researchers.

6 Feb 2013

Epidemiology model supports 20:80 transmission rule in HCV

A new hepatitis C virus transmission model combining genetic and epidemiologic data reveals that the majority of transmission of the virus is by a minority of intravenous drug users.

4 Feb 2013

Ultrasound signs can predict Down’s syndrome

Ultrasound markers that can be detected in the second trimester of pregnancy are strongly predictive for Down’s syndrome, show findings from a systematic review and meta-analysis.

4 Feb 2013

Gene variant boosts ulcer susceptibility in NSAID users

A single nucleotide polymorphism in the cytochrome P450 2C gene cluster influences the risk for peptic ulcer disease in people taking non-steroidal anti-inflammatory drugs, a study reveals.

31 Jan 2013

Finding medical applications for unused inventions: an interview with Gabriel Mecklenburg, Co-Founder of Marblar

Marblar is gamifying the process of technology transfer. We post technology on our platform in the form of a challenge, and the Marblar community then competes to uncover new problems these technologies could solve – thereby discovering new market applications for these technologies.

31 Jan 2013

Five genes hold key to meningioma make up

Research published in Science shows that mutations in five genes characterize most meningiomas.

28 Jan 2013

BPA-containing resin not needed to bond retainers

Metal lingual retainers can be bonded successfully without the use of composite liquid resin, a study by Chinese researchers indicates.

28 Jan 2013

IRHOM2-targeted drugs can effectively treat patients with rheumatoid arthritis

Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis (RA), a protein known as IRHOM2. The finding could provide an effective and potentially less toxic alternative therapy to tumor necrosis factor-alpha blockers (TNF-blockers), the mainstay of treatment for rheumatoid arthritis, and could help patients who do not respond to this treatment. Efforts to develop drugs that hone in on this new target are underway.

28 Jan 2013

Researchers study innovative stem cell drug for treating localized cartilage damage

Rush University Medical Center is conducting the nation's first clinical study of an innovative stem cell drug, Cartistem, to repair knee cartilage damaged by aging, trauma or degenerative diseases such as osteoarthritis.

25 Jan 2013

KLF6-SV1 gene variant drives the spread of breast cancer

A team of researchers led by Goutham Narla, MD, PhD, at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, and collaborators at the Mount Sinai School of Medicine and Erasmus Medical Center, have discovered a gene variant that drives the spread of breast cancer.

23 Jan 2013

Russia approves FzioMed’s Oxiplex gel for lumbar spine surgery

FzioMed, a privately held medical device company based in San Luis Obispo, CA., is pleased to announce the approval of Oxiplex in Russia. Oxiplex is an absorbable, clear, viscoelastic gel that is applied during lumbar spine surgery immediately prior to wound closure.

22 Jan 2013

Winning the genetic body odor lottery could save on deodorant

Research shows that people who have two copies of the minor allele of a single nucleotide polymorphism found in the ABCC11 gene could save money on deodorant as they are genetically odorless.

21 Jan 2013

Ceram to develop its Controlled Release Technology for the delivery of selected AstraZeneca compounds

AstraZeneca, a global pharmaceutical company, has signed an agreement with Ceram Research Ltd, the international materials development company, for Ceram to develop its Inorganic-based Controlled Release Technology in a feasibility study for the delivery of selected AstraZeneca compounds.

18 Jan 2013

Jersey Shore University Medical Center launches Meridian Executive Health program

Jersey Shore University Medical Center announces the launch of the Meridian Executive Health program, a health care pilot initiative designed for busy individuals whose schedule demands a streamlined but high quality experience.

17 Jan 2013

Tailored asthma therapy on the horizon

UK researchers report that montelukast therapy is more effective than salmeterol in children with asthma who have a particular genotype – a finding that could pave the way for personalized asthma management.

15 Jan 2013