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D737 compound restores motor function and longevity in fruit flies with Alzheimer's

An efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease, according to new research that could help put the search for an effective Alzheimer's drug on a faster track.

16 Nov 2012

Cook receives FDA approval for Zilver PTX Drug-Eluting Peripheral Stent to treat PAD

The U.S. Food and Drug Administration approved the Zilver PTX Drug-Eluting Peripheral Stent (Zilver PTX Stent), the first drug-eluting stent indicated to re-open a particular artery in the thigh (femoropopliteal artery) when narrowed or blocked as a result of peripheral artery disease (PAD).

15 Nov 2012

Tuberculosis pathogen has an ingenious defence mechanism against oxygen

Flemish biologists lead by Joris Messens (VIB / Vrije Universiteit Brussel) have discovered that Mycobacterium tuberculosis - the bacterium that causes tuberculosis - has an ingenious defence mechanism against oxygen. This knowledge is important in the search for a treatment for tuberculosis. 9.4 million people are infected with tuberculosis annually and 1.7 million people die as a result.

15 Nov 2012

Study evaluates benefits of HBO2 therapy on post-concussion symptoms in military personnel with TBI

The average incidence of traumatic brain injury (TBI) among service members deployed in Middle East conflict zones has increased 117% in recent years, mainly due to proximity to explosive blasts. Therapeutic exposure to a high oxygen environment was hoped to minimize the concussion symptoms resulting from mild TBI, but hyperbaric oxygen (HBO2) treatment may not offer significant advantages, according to an article in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

14 Nov 2012

Atpif1 gene regulates heme synthesis in red blood cell formation

Scientists at the University of Georgia, Harvard Medical School and the University of Utah have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood.

14 Nov 2012

Antioxidant imbalance in abnormal sperm

An imbalance exists in oxidative stress markers, such as reactive nitrogen species, reactive oxygen species, and total antioxidant capacity, in infertile men with abnormal semen parameters, report researchers.

13 Nov 2012

New England Journal of Medicine publishes BMC's capnography training video

Physicians at Boston Medical Center (BMC) have developed a training video for health care providers about how to effectively use capnography to monitor ventilation and carbon dioxide levels for patients under anesthesia or conscious sedation. This is the sixth video published in the New England Journal of Medicine's Videos in Clinical Medicine section produced by BMC. It highlights the importance of using capnography to increase patient safety.

9 Nov 2012

Low antioxidant levels contribute to increased blood pressure during exercise for people with PAD

Low antioxidant levels contribute to increased blood pressure during exercise for people with peripheral arterial disease, according to researchers at Penn State Hershey Heart and Vascular Institute.

8 Nov 2012

Autologous stem cells do not improve heart function when given three weeks after heart attack

Administering stem cells derived from patients' own bone marrow either three or seven days after a heart attack is safe but does not improve heart function six months later, according to a clinical trial supported by the National Institutes of Health (NIH).

8 Nov 2012

Atpif1 gene regulates hemoglobin synthesis during red blood cell formation

Researchers at Brigham and Women's Hospital (BWH) have discovered a new gene that regulates hemoglobin synthesis during red blood cell formation. The findings advance the biomedical community's understanding and treatment of human anemias and mitochondrial disorders.

7 Nov 2012

Excessive turnover of placental cells may trigger unnatural increase in blood pressure

Excessive turnover of cells in the placenta may trigger an unnatural increase in blood pressure that puts mother and baby at risk, researchers say.

7 Nov 2012

MASP-1 enzyme plays a central role in activating the complement system

Researchers from Aarhus University, Denmark, have now discovered an important mechanism behind one of our most fundamental lines of immune function. The discovery has been published in the esteemed scientific journal, The Journal of Immunology, where it has been highlighted as a top story.

7 Nov 2012

Turning off GSK-3α protein activity can prevent heart remodeling

When a person has a heart attack, portions of the heart muscle die in the next several days or even weeks if deprived of oxygen for long enough. The recovering heart slowly remodels itself, even fostering the growth of new blood vessels, in an attempt to regain some of its former function. But all too often, the remodeling is actually harmful, and the damaged heart is on an inevitable downward slide to heart failure.

6 Nov 2012

Hospital quality may affect infant morbidity

Birth in or postnatal transfer to hospitals with a lower level of resources and facilities may negatively impact the health of very preterm infants, show research findings.

6 Nov 2012

Physical exercise may help preserve mobility in Parkinson’s patients

Aerobic and resistance exercise significantly improve fitness, gait speed, and muscle strength in patients with Parkinson’s disease, shows research published in the Archives of Neurology.

6 Nov 2012

Comprehensive overview of vascular risk factors to Alzheimer's disease

Over the last 15 years, researchers have found a significant association between vascular diseases such as hypertension, atherosclerosis, diabetes type 2, hyperlipidemia, and heart disease and an increased risk of Alzheimer's disease.

6 Nov 2012

Comprehensive review article on baroreflex sensitivity after SCI

Spinal cord injury (SCI) can disrupt the body's sensitive signaling mechanisms that control blood pressure, breathing, and oxygen delivery to the heart and other organs during changes in body position. Cardiovascular (CV) disease is a leading cause of illness and death following SCI, and changes in baroreflex sensitivity-the body's ability to detect and respond to changes in blood pressure-may be predictive of a CV event.

6 Nov 2012

Genkyotex announces positive results from GKT137831 Phase I studies on healthy subjects

Genkyotex, the leading developer of NOX inhibitors to treat oxygen-radical mediated diseases, announced today that Phase I studies have demonstrated excellent safety and tolerability following single and multiple oral doses of GKT137831, the first in class NOX 1 and 4 inhibitor. In addition, GKT137831 demonstrated a favourable pharmacokinetic profile in these subjects.

3 Nov 2012

XJB-5-131 compound suppresses symptoms of Huntington's in mice

There's new hope in the fight against Huntington's disease. A group of researchers that includes scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.

2 Nov 2012

Malarial drug shows promise in stopping breast cancer

A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.

2 Nov 2012

Oxygen News and Research

D737 compound restores motor function and longevity in fruit flies with Alzheimer's

Cook receives FDA approval for Zilver PTX Drug-Eluting Peripheral Stent to treat PAD

Tuberculosis pathogen has an ingenious defence mechanism against oxygen

Study evaluates benefits of HBO2 therapy on post-concussion symptoms in military personnel with TBI

Atpif1 gene regulates heme synthesis in red blood cell formation

Antioxidant imbalance in abnormal sperm

New England Journal of Medicine publishes BMC's capnography training video

Low antioxidant levels contribute to increased blood pressure during exercise for people with PAD

Autologous stem cells do not improve heart function when given three weeks after heart attack

Atpif1 gene regulates hemoglobin synthesis during red blood cell formation

Excessive turnover of placental cells may trigger unnatural increase in blood pressure

MASP-1 enzyme plays a central role in activating the complement system

Turning off GSK-3α protein activity can prevent heart remodeling

Hospital quality may affect infant morbidity

Physical exercise may help preserve mobility in Parkinson’s patients

Comprehensive overview of vascular risk factors to Alzheimer's disease

Comprehensive review article on baroreflex sensitivity after SCI

Genkyotex announces positive results from GKT137831 Phase I studies on healthy subjects

XJB-5-131 compound suppresses symptoms of Huntington's in mice

Malarial drug shows promise in stopping breast cancer

Oxygen Measurement eBook - Easily Understand Dissolved Oxygen Measurement eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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