Pancreatic Cancer News and Research

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Pancreatic cancer is the fourth leading cause of all cancer deaths in the United States and the third leading cause of cancer deaths in individuals ages 40 to 60. Approximately 37,000 Americans are diagnosed with pancreatic cancer each year, and, each year, approximately the same number die from it. Often, pancreatic cancer is found too late for surgical intervention, and chemotherapy and radiation treatments have little effect.

Umbrella review assesses the association between artificially sweetened beverages and health outcomes

A recent umbrella review evaluated the associations between ASBs and health outcomes.

6 Jun 2023

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Three clinical trials led by researchers at The University of Texas MD Anderson Cancer Center demonstrated positive results from the targeted therapy erdafitinib for patients with multiple tumor types harboring FGFR alterations.

5 Jun 2023

Tumors in distant organs remotely reprogram the liver

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying functions, according to a study from investigators at Weill Cornell Medicine.

25 May 2023

New method can kill aggressive brain tumors

Researchers at the University of Gothenburg, working with French colleagues, have successfully developed a method able to kill the aggressive brain tumor glioblastoma.

25 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

22 May 2023

Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

A new clinical trial is testing the effectiveness of chemotherapy treatment following surgery for a subset of pancreatic cancer patients.

19 May 2023

New liquid biopsy tool shows 30% increased sensitivity in detecting ctDNA

Pancreatic cancer is the seventh leading cause of cancer death worldwide and despite the increasing incidence of this disease, effective treatments are lacking and prognosis for patients with this tumor type remains poor, with approximately 70% of patients dying within one year of diagnosis.

16 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

Break Through Cancer funds AML research at MD Anderson

The University of Texas MD Anderson Cancer Center was awarded more than $5.7 million in grants from Break Through Cancer to support collaborative research teams working to discover novel molecular targets to eradicate minimal residual disease in acute myeloid leukemia (AML) and to treat clonal hematopoiesis, a precursor to AML.

16 May 2023

Metabolically healthy and unhealthy 'forms' of obesity linked with increased risk of obesity-related cancers

New research to be presented at this coming week's European Congress on Obesity in Dublin, Ireland (17-20 May) and published in the Journal of the National Cancer Institute shows that both the metabolically healthy and unhealthy 'forms' of obesity are associated with an increased risk of various obesity-related cancers, with the relationship stronger in metabolically unhealthy obesity.

15 May 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

Research sheds light on the early cellular events that give rise to pancreatic cancer

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

11 May 2023

New AI-powered, laser-based breathalyzer can detect COVID-19 in real-time

With each breath, humans exhale more than 1,000 distinct molecules, producing a unique chemical fingerprint or "breathprint" rich with clues about what's going on inside the body.

10 May 2023

Can artificial intelligence help predict the risk of pancreatic cancer using disease trajectories?

Researchers designed surveillance programs for the early detection of patients at elevated risk of pancreatic cancer.

10 May 2023

AI-based population screening could expedite the diagnosis of pancreatic cancer

An artificial intelligence tool has successfully identified people at the highest risk for pancreatic cancer up to three years before diagnosis using solely the patients' medical records, according to new research led by investigators at Harvard Medical School and the University of Copenhagen, in collaboration with VA Boston Healthcare System, Dana-Farber Cancer Institute, and the Harvard T.H. Chan School of Public Health.

8 May 2023

Pancreatic Cancer News and Research

Further Reading

Umbrella review assesses the association between artificially sweetened beverages and health outcomes

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Tumors in distant organs remotely reprogram the liver

New method can kill aggressive brain tumors

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

Clinical trial tests effectiveness of chemotherapy after surgery for pancreatic neuroendocrine tumors

New liquid biopsy tool shows 30% increased sensitivity in detecting ctDNA

Study establishes a mechanistic link between obesity and oral cancer immune escape

Break Through Cancer funds AML research at MD Anderson

Metabolically healthy and unhealthy 'forms' of obesity linked with increased risk of obesity-related cancers

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Research sheds light on the early cellular events that give rise to pancreatic cancer

New AI-powered, laser-based breathalyzer can detect COVID-19 in real-time

Can artificial intelligence help predict the risk of pancreatic cancer using disease trajectories?

AI-based population screening could expedite the diagnosis of pancreatic cancer

Unique treatment can eradicate pancreatic tumors while stopping cancer progression

Researchers explore the role of a genetic process in pancreatic cancer

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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