Paralysis News and Research

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Paralysis is the loss of muscle function in part of your body. It happens when something goes wrong with the way messages pass between your brain and muscles. Paralysis can be complete or partial. It can occur on one or both sides of your body. It can also occur in just one area, or it can be widespread. Paralysis of the lower half of your body, including both legs, is called paraplegia. Paralysis of the arms and legs is quadriplegia.

Researchers isolate gene mutations in patients with inherited amyotrophic lateral sclerosis

Researchers at the University of Massachusetts Medical School (UMMS) have discovered a new gene whose mutations cause familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.

26 Feb 2009

New gene associated with Lou Gehrig's disease

A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King's College London (KCL) has identified a novel gene for inherited amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

26 Feb 2009

Significant Rett syndrome discovery

A paper published online today in Nature Neuroscience reveals the presence of methyl CpG binding protein 2 (MeCP2) in glia. MeCP2 is a protein associated with a variety of neurological disorders, including Rett Syndrome, the most physically disabling of the autism spectrum disorders.

23 Feb 2009

Robotic therapy may reduce stroke physical disability years later

Robot-assisted therapy may help stroke patients attain gains in their physical abilities long after the stroke, according to research presented at the American Stroke Association's International Stroke Conference 2009.

20 Feb 2009

HPV vaccine does not increase the risk of developing Guillain-Barré syndrome

The HPV vaccine does not increase the risk of developing Guillain-Barré syndrome, according to a study released today that will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009.

16 Feb 2009

Statins may treat cerebral cavernous malformation

In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol.

27 Jan 2009

Lou Gehrig's disease in humans has genetic links to degenerative myelopathy in dogs

An incurable, paralyzing disease in humans is now genetically linked to a similar disease in dogs.

21 Jan 2009

New nasal spray vaccine shown to be effective against botulism

A preclinical study found a new nasal spray vaccine to provide complete protection against a major botulism toxin, according to a study published today in the Nature journal Gene Therapy .

8 Jan 2009

All VX nerve agent munitions destroyed in U.S.

The U.S. Army Chemical Materials Agency (CMA) marked the destruction of all VX nerve agent munitions at its destruction sites on Wednesday, Dec. 24, 2008.

30 Dec 2008

Patient-derived induced stem cells retain disease traits

The dying cells - the same type lost in patients with the devastating neurological disease spinal muscular atrophy - confirmed that the University of Wisconsin-Madison stem cell biologist had recreated the hallmarks of a genetic disorder in the lab, using stem cells derived from a patient.

22 Dec 2008

Neuralstem files IND for amyotrophic lateral sclerosis stem cell trial

Neuralstem, Inc. announced this morning that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) to begin a clinical trial to treat amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

18 Dec 2008

Magnetic resonance diffusion tensor imaging predicts effects of multiple sclerosis flare-ups on optic nerve

One of the most pernicious aspects of multiple sclerosis (MS) - its sheer unpredictability - may finally be starting to yield to advanced medical imaging techniques.

17 Dec 2008

MRI scans can predict effects of multiple sclerosis 'flare-ups' on optic nerve

One of the most pernicious aspects of multiple sclerosis (MS) - its sheer unpredictability - may finally be starting to yield to advanced medical imaging techniques.

16 Dec 2008

Australians warned of rabies outbreak in Bali

The warning comes from the head of the Northern Territory's Centre for Disease Control, Dr. Peter Markey, who says anyone bitten or scratched on the island by an animal should seek medical advice; the warning also applies to people who have been to Bali recently.

14 Dec 2008

Carrier screening for spinal muscular atrophy should be offered to all couples

Carrier screening for spinal muscular atrophy (SMA) - a serious genetic disease affecting approximately 1 in 10,000 infants that causes progressive muscle weakness and death - should be made available to all families, according to a new practice guideline issued by the American College of Medical Genetics (ACMG).

10 Dec 2008

Motor neurons derived from human embryonic stem cells provide insight into ALS

Two new research studies use motor neurons derived from human embryonic stem (hES) cells to demonstrate that multiple toxic pathways contribute to the devastating degeneration associated with Amyotrophic Lateral Sclerosis (ALS) and that protective therapeutics will need to oppose the disease on multiple fronts.

3 Dec 2008

Researchers develop human embryonic stem cell-based system for modeling ALS

Long thought of as mere bystanders, astrocytes are crucial for the survival and well-being of motor neurons, which control voluntary muscle movements.

3 Dec 2008

Signs of stroke - most people ignorant

A Mayo Clinic study shows a majority of stroke patients don't think they're having a stroke -- and as a result -- delay seeking treatment until their condition worsens.

25 Nov 2008

Cytori announces seven new investigator-initiated clinical studies in Japan

All seven studies are investigator-initiated and to be performed under local and country guidelines. Cytori, who will not sponsor these studies, will continue work with country authorities, such as the Ministry of Health and Labor in Japan, to obtain specific regulatory approvals for its products.

19 Nov 2008

Researchers use embryonic stem cells from mice to grow motor neurons

Dalhousie Medical School researchers have discovered that embryonic stem cells may play a critical role in helping people with nerve damage and motor neuron diseases, such as amyotrophic lateral sclerosis (ALS), regain muscular strength.

19 Nov 2008