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Oral pathogen linked to increased risk of heart rupture after heart attack

Researchers from Tokyo Medical and Dental University(TMDU) find that a periodontal pathogen, Porphyromonas gingivalis, inhibits autophagosome–lysosome fusion, and can therefore worsen cardiac remodeling and cause cardiac rupture after myocardial infarction.

19 Oct 2023

Researchers profile new drug combinations to fight antibiotic-resistant bacteria

Antimicrobial resistance – occurring when pathogens can survive antibiotic treatment – is one of the most rapidly emerging global public health threats today.

19 Oct 2023

Blue light technology to combat surface contamination by foodborne pathogens

How effectively antimicrobial blue light (aBL) inactivated dried cells and biofilms.

19 Oct 2023

Children's immune system better prepared to defend against SARS-CoV-2, study finds

Why are severe courses of SARS-CoV-2 infection much less common in children and adolescents than in adults? Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now discovered that the immune system in the upper respiratory tract is much more alert and active in children before infection than in adults and is therefore better equipped to fight the virus.

18 Oct 2023

Researchers develop experimental vaccine to prevent spread of metastatic cancers to the lungs

Engineers at the University of California San Diego have developed an experimental vaccine that could prevent the spread of metastatic cancers to the lungs.

18 Oct 2023

Strengthening the immune system to fight cytomegalovirus on its own

Some viruses can be dormant throughout a person's life and cause no harm but become dangerous when the immune system is weakened.

17 Oct 2023

Public health interventions prevented most SARS-CoV-2 introductions from leading to outbreaks

SARS-CoV-2, the causative agent of COVID-19, began impacting the U.S. in March 2020 with many schools and universities shifting to remote education by early April 2020 in response to the public health emergency.

17 Oct 2023

NIAID grant supports research aimed at improving outcomes for patients with Aspergillus infections

Aspergillus fumigatus is the major airborne fungus present indoors and outdoors that causes various diseases, the severity of which are dependent on an individual's immune status.

17 Oct 2023

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

The success and challenges of developing different tuberculosis (TB) vaccine types.

17 Oct 2023

Acinetobacter baumannii can fall into a deep sleep to survive harsh conditions

A research team led by Beate Averhoff and Volker Müller of Goethe University Frankfurt has discovered a fundamental mechanism that helps the dreaded hospital pathogen Acinetobacter baumannii to survive.

16 Oct 2023

Lab-grown skin organoids help scientists understand monkeypox infection

Skin organoids offer a powerful platform for drug discovery in the ongoing fight against the virus formerly known as monkeypox.

16 Oct 2023

Antibiotic-resistant bacteria in Ghana confined to clinical settings

Calland, J. K., et al. (2023). Population structure and antimicrobial resistance among Klebsiella isolates sampled from human, animal, and environmental sources in Ghana: a cross-sectional genomic One Health study. The Lancet Microbe. doi.org/10.1016/S2666-5247(23)00208-2.

16 Oct 2023

Study reveals previously unappreciated role for innate immune cells in early stages of TB infection

A new study from the University of Pittsburgh Center for Vaccine Research published today in the Journal of Experimental Medicine describes a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.

16 Oct 2023

Study shows widespread prevalence of dangerous pathogens in ventilated patients

University of Maryland School of Medicine (UMSOM) researchers conducted a statewide survey of all patients on breathing machines in hospitals and long-term care facilities and found that a significant percentage of them harbored two pathogens known to be life-threatening in those with compromised immune systems.

15 Oct 2023

Study identifies significant percentage of ventilated patients colonized with life-threatening pathogens

13 Oct 2023

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation.

11 Oct 2023

Nasal mupirocin found to be highly effective at preventing Staphylococcus aureus infections in critically ill patients

A large multi-state study by the Centers for Disease Control and Prevention, the Harvard Pilgrim Health Care Institute, HCA Healthcare, and the University of California, Irvine has found that a nasal antibiotic ointment, mupirocin, which is currently used daily for intensive care unit (ICU) patients in only one-third of U.S. hospitals, is highly effective at preventing Staphylococcus aureus infections in critically ill patients, outperforming an antiseptic solution.

10 Oct 2023

RSV in seniors: Less common than COVID-19, but hits harder, CDC study reveals

In a recent CDC's MMWR study, researchers found that while respiratory syncytial virus (RSV) infections are less common than COVID-19 and influenza in Americans aged 60+ years, they result in much more severe clinical outcomes. This insight supports the CDC's recommendation for RSV vaccination in older adults, emphasizing its potential in preventing severe respiratory disease.

10 Oct 2023

Halting pandemics at the source: The call for a proactive 'One Health' approach

The recent PLoS Pathogens review emphasizes proactively preventing pathogen spillover from animals to humans as a strategy against future pandemics, advocating for a holistic One Health approach that considers the interconnectedness of humans, animals, and the environment. The study underscores the importance of primary prevention, differentiating it from secondary containment, and highlights the economic and societal benefits of preemptive actions over reactive responses.

10 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Pathogen News and Research

Oral pathogen linked to increased risk of heart rupture after heart attack

Researchers profile new drug combinations to fight antibiotic-resistant bacteria

Blue light technology to combat surface contamination by foodborne pathogens

Children's immune system better prepared to defend against SARS-CoV-2, study finds

Researchers develop experimental vaccine to prevent spread of metastatic cancers to the lungs

Strengthening the immune system to fight cytomegalovirus on its own

Public health interventions prevented most SARS-CoV-2 introductions from leading to outbreaks

NIAID grant supports research aimed at improving outcomes for patients with Aspergillus infections

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

Acinetobacter baumannii can fall into a deep sleep to survive harsh conditions

Lab-grown skin organoids help scientists understand monkeypox infection

Antibiotic-resistant bacteria in Ghana confined to clinical settings

Study reveals previously unappreciated role for innate immune cells in early stages of TB infection

Study shows widespread prevalence of dangerous pathogens in ventilated patients

Study identifies significant percentage of ventilated patients colonized with life-threatening pathogens

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

Nasal mupirocin found to be highly effective at preventing Staphylococcus aureus infections in critically ill patients

RSV in seniors: Less common than COVID-19, but hits harder, CDC study reveals

Halting pandemics at the source: The call for a proactive 'One Health' approach

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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