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Whole-genome sequencing and sharing real-time data could limit spread of foodborne bacteria

Employing advanced genetic-tracing techniques and sharing the data produced in real time could limit the spread of bacteria -- Bacillus cereus -- which cause foodborne illness, according to researchers who implemented whole-genome sequencing of a pathogen-outbreak investigation.

14 Feb 2019

Researchers comprehensively sequence the human immune system

For the first time ever, researchers are comprehensively sequencing the human immune system, which is billions of times larger than the human genome. In a new study published in Nature from the Human Vaccines Project, scientists have sequenced a key part of this vast and mysterious system -- the genes encoding the circulating B cell receptor repertoire.

14 Feb 2019

Microbiologists identify enzyme that makes Helicobacter so adaptable

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet Munich microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

13 Feb 2019

New AI-driven platform analyze how pathogens infect human cells

Researchers have developed a new AI-driven platform that can analyze how pathogens infect our cells with the precision of a trained biologist.

13 Feb 2019

New bioengineered device enhances the production of T-cells

Bone marrow transplants, also known as hematopoietic stem cell transplants, are life-saving treatments for aggressive diseases, such as leukemia and multiple myeloma, and infections such as HIV. The procedure entails infusion of blood stem cells from a matched donor into the patient to 'reset' the blood and immune system.

12 Feb 2019

Inhibiting tuberculosis-induced cell death with immunotherapy

Tuberculosis treatment still entails the intake several antibiotics over a period of many months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy treatment, and side effects frequently lead to a discontinuation of treatment and high mortality rates.

12 Feb 2019

New research sheds fresh light on the history of malaria

The anopheline mosquitoes that carry malaria were present 100 million years ago, new research shows, potentially shedding fresh light on the history of a disease that continues to kill more than 400,000 people annually.

12 Feb 2019

Scientists develop novel way with genome sequences to study widespread form of malaria

Scientists at the Institute of Genome Sciences at the University of Maryland School of Medicine have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria. P. vivax is a single-celled transmitted by mosquitoes.

11 Feb 2019

Researchers find how Aspergillus fumigatus knocks out immune defenses

Research team from the University of Jena clarifies the mechanism of gliotoxin, a mycotoxin from the fungus Aspergillus fumigatus. The researchers present their findings in the current issue of the specialist journal Cell Chemical Biology

11 Feb 2019

Therapy derived from parasitic worms helps protect against one of chemotherapy's side effects

A therapy derived from the eggs of parasitic worms helps to protect against one of chemotherapy's debilitating side effects by significantly downregulating major proinflammatory pathways and reducing inflammation, indicates the first transcriptome-wide profiling of the bladder during ifosfamide-induced hemorrhagic cystitis.

8 Feb 2019

Scientists receive $1.5 million to develop new technology for detecting healthcare-associated infections

Healthcare-associated infections are the fourth leading cause of death in Canada, predicted to move up to second place by 2050.

8 Feb 2019

Caltech scientists develop new methods for rapidly determining T cell targets

The human body's immune system is like a vast team of special agents. Certain cells called T cells each individually specialize in recognizing a particular intruder, such as the influenza virus or salmonella.

8 Feb 2019

Researchers reveal novel computational tool used to analyze genetic variation

The field of genetic sequencing has undergone a dramatic revolution over the past 20 years. In 2001 the first copy of the three billion base pairs that assemble the human genome was published.

8 Feb 2019

Inaccurate tests carried out on tuberculosis patients lead to high mortality rate

Inaccurate tests carried out on tuberculosis patients in developing countries often fail to reliably detect resistance to drugs, leading to incorrect treatment and a higher mortality rate.

8 Feb 2019

New research on viral biology could lead to efficient vaccines against leishmaniasis

New research from McGill University has found that a virus infecting the Leishmania parasite spreads by exploiting a mechanism used for cell-to-cell communication, a discovery that could pave the way to new vaccines against infections that cause severe disfiguration.

8 Feb 2019

Kansas geologist reveals startling global spread of antibiotic-resistant microbes

A University of Kansas geologist's work in the remote High Arctic of Norway has exposed the startling global spread of antibiotic-resistant microbes -- including multidrug-resistant "superbugs" -- that could have dire implications for human health worldwide.

6 Feb 2019

Study uncovers how lung tissue remodels to support immune response to influenza

Immunology researchers at the Babraham Institute have discovered how lung tissue in mice is remodelled in response to infection with influenza in order to support an immune system response.

6 Feb 2019

New disease surveillance tool enables early detection of viral outbreaks

During the Zika virus outbreak of 2015-16, public health officials scrambled to contain the epidemic and curb the pathogen's devastating effects on pregnant women. At the same time, scientists around the globe tried to understand the genetics of this mysterious virus.

5 Feb 2019

Researchers harness immune system to reveal new clues to produce HIV vaccine

The immune system is the body's best defense in fighting diseases like HIV and cancer. Now, an international team of researchers is harnessing the immune system to reveal new clues that may help in efforts to produce an HIV vaccine.

4 Feb 2019

Insect-borne microbes outperform soil bacteria in stopping certain dangerous antibiotic-resistant pathogens

Medicine was transformed in the 20th century by the discovery and development of antibiotics, the vast majority of which came from one source: soil bacteria.

4 Feb 2019

Pathogen News and Research

Whole-genome sequencing and sharing real-time data could limit spread of foodborne bacteria

Researchers comprehensively sequence the human immune system

Microbiologists identify enzyme that makes Helicobacter so adaptable

New AI-driven platform analyze how pathogens infect human cells

New bioengineered device enhances the production of T-cells

Inhibiting tuberculosis-induced cell death with immunotherapy

New research sheds fresh light on the history of malaria

Scientists develop novel way with genome sequences to study widespread form of malaria

Researchers find how Aspergillus fumigatus knocks out immune defenses

Therapy derived from parasitic worms helps protect against one of chemotherapy's side effects

Scientists receive $1.5 million to develop new technology for detecting healthcare-associated infections

Caltech scientists develop new methods for rapidly determining T cell targets

Researchers reveal novel computational tool used to analyze genetic variation

Inaccurate tests carried out on tuberculosis patients lead to high mortality rate

New research on viral biology could lead to efficient vaccines against leishmaniasis

Kansas geologist reveals startling global spread of antibiotic-resistant microbes

Study uncovers how lung tissue remodels to support immune response to influenza

New disease surveillance tool enables early detection of viral outbreaks

Researchers harness immune system to reveal new clues to produce HIV vaccine

Insect-borne microbes outperform soil bacteria in stopping certain dangerous antibiotic-resistant pathogens

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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