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Machine learning unlocks secrets of antimicrobial resistance, identifying over 900 key genes

Researchers employed advanced techniques like gene annotation, pangenomics, and machine learning to identify over 900 genes responsible for antimicrobial resistance in 12 bacterial species, outperforming traditional identification methods. This breakthrough approach offers new insights into the genetic basis of resistance, potentially guiding the development of more effective antibiotics

27 Nov 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

Scientists succeed in mapping a central part of the immune system

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system - the HLA class II molecules - while accurately predicting how they display fragments of pathogens on the surface of cells.

24 Nov 2023

New insights into how SARS-CoV-2 evades our immune system

This review in Cellular and Molecular Immunology delves into the innate immune response to SARS-CoV-2, exploring how the virus evades immunity and the potential role of innate immunity in long-COVID and vaccine responses, shedding light on future therapeutic strategies.

23 Nov 2023

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism -; the intrinsic link between metabolism in immune cells and their immune function.

20 Nov 2023

Kiwi cafés sizzle with success on meat-free mondays, cooking up environmental change

Study explores the implementation and support of Meat-Free Mondays in New Zealand's hospital cafés, finding strong participation and environmental concerns as key drivers while identifying knowledge gaps and taste preferences as main barriers to its success.

20 Nov 2023

Study finds high levels of enteric pathogens in children from Alabama's rural areas, highlights sanitation issues

The study reveals a significant presence of enteric pathogens in children from Alabama's Black Belt region, linking well water consumption to increased pathogen detection and underscoring the need for improved sanitation infrastructure.

19 Nov 2023

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Promising new cancer therapy appears to be extremely potent against tuberculosis

A promising new cancer therapy also appears extremely potent against one of the world's most devastating infectious diseases: tuberculosis (TB).

16 Nov 2023

Oral antibiotic taken once-daily for six months reduces risk of developing drug-resistant TB

Two landmark clinical trials reported today at the Union meeting showed that an oral antibiotic taken for six months once-daily substantially reduced the risk of developing drug-resistant TB.

16 Nov 2023

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

An interview with Dr Beverley Isherwood.

16 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test-;a phenomenon known as virologic rebound.

13 Nov 2023

Study unravels the molecular mechanisms underlying influenza B virus pathogenicity

Announcing a new article publication for Zoonoses journal. Influenza B virus is a significant respiratory pathogen responsible for seasonal influenza.

13 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

New study sheds light on the genes and nutrients that give MAIT cells their fighting power

Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented type of T cell.

10 Nov 2023

Pediatric viral threats surge in the 21st century: A call for One Health approach

Scoping review in "Pediatric Research" examines the rise of pediatric viral diseases in the 21st century and underscores the importance of a One Health approach, integrating human, animal, and ecosystem health, to combat these emerging and re-emerging infectious threats effectively.

9 Nov 2023

Human tissue model reveals diversity of bacterial strategies for urinary tract infections

The research, published today in Science Advances, is the first to use a sophisticated human tissue model to explore the interaction between host and pathogen for six common species that cause urinary tract infections.

8 Nov 2023

New antifungal molecule shows promise in combatting fungal infections without toxicity

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

8 Nov 2023

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

This research paper delves into the risks of contamination in ready-to-eat fruits and vegetables by enteric pathogens like E. coli, Salmonella, and Listeria, which can lead to foodborne illnesses. It also explores the contamination sources and plant-pathogen interactions, emphasizing the importance of improved safety measures in the food supply chain.

6 Nov 2023

Researchers identify a 'Threshold of Immunity' to SARS-CoV-2

How much immunity do we need against COVID-19? New international research led by scientists in Ireland and published in Nature Communications, has identified a 'Threshold of Immunity' to SARS-CoV-2.

6 Nov 2023

Pathogen News and Research

Machine learning unlocks secrets of antimicrobial resistance, identifying over 900 key genes

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Scientists succeed in mapping a central part of the immune system

New insights into how SARS-CoV-2 evades our immune system

Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

Kiwi cafés sizzle with success on meat-free mondays, cooking up environmental change

Study finds high levels of enteric pathogens in children from Alabama's rural areas, highlights sanitation issues

Unraveling the immune system's response to nanoparticle drug delivery

Promising new cancer therapy appears to be extremely potent against tuberculosis

Oral antibiotic taken once-daily for six months reduces risk of developing drug-resistant TB

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Study unravels the molecular mechanisms underlying influenza B virus pathogenicity

Revolutionizing critical care: the potential of gut microbiota therapeutics

New study sheds light on the genes and nutrients that give MAIT cells their fighting power

Pediatric viral threats surge in the 21st century: A call for One Health approach

Human tissue model reveals diversity of bacterial strategies for urinary tract infections

New antifungal molecule shows promise in combatting fungal infections without toxicity

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

Researchers identify a 'Threshold of Immunity' to SARS-CoV-2

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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