Periodontitis News and Research

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Hidden dental root tip infections may increase risk of coronary artery disease

According to a study carried out at the University of Helsinki, an infection of the root tip of a tooth increases the risk of coronary artery disease, even if the infection is symptomless.

2 Aug 2016

New study finds link between periodontal disease and lacunar stroke

A new study has revealed a relationship between chronic periodontitis and lacunar infarct, two common diseases in the elderly. Chronic periodontitis is an inflammatory disease of the gums, whereas lacunar infarct is a type of cerebral small vessel disease that can lead to a stroke.

19 Jul 2016

Overweight and obesity increase risk for periodontitis

Today at the 94th General Session & Exhibition of the International Association for Dental Research, researcher Marco Peres, The University of Adelaide, South Australia, will present a study titled "Overweight and Obesity Impact on Periodontitis: A Brazilian Birth Cohort."

24 Jun 2016

Cigarette smoke promotes bacteria colonization, immune invasion

The mouth is one of the "dirtiest" parts of the body, home to millions of germs. But puffing cigarettes can increase the likelihood that certain bacteria like Porphyromonas gingivalis will not only set up camp but will build a fortified city in the mouth and fight against the immune system.

1 Jun 2016

Specific oral microbiome linked to pancreatic cancer risk

The presence of certain bacteria in the mouth may reveal increased risk for pancreatic cancer and enable earlier, more precise treatment. This is the main finding of a study led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center to be presented April 19 in New Orleans at the annual meeting of the American Association for Cancer Research.

20 Apr 2016

Antimicrobial silicon nitride holds promise as therapeutic aid for treating periodontitis

Severe gum disease known as periodontitis can lead to tooth loss, and treating it remains a challenge. But new approaches involving silicon nitride, a ceramic material used in spinal implants, could be on the way. The surface of silicon nitride has a lethal effect on the bacteria that commonly cause periodontitis. Now scientists, reporting in ACS' journal Langmuir, are examining why this happens. Their findings could help inform future efforts to treat the disease.

7 Apr 2016

Study finds correlation between male sex hormones and oral health

More than 20 species of macaques, the most widely distributed nonhuman primates in the world, socialize in lively troops and make frequent appearances on National Geographic documentaries. But, what can we learn from one of our closest primate relatives about our own oral health?

31 Mar 2016

Study shows aging affects adaptive immune responses

Today at the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Jeffrey Ebersole, University of Kentucky, Lexington, USA, will present a study titled "Systemic Antibody Responses to Oral Bacteria with Aging." The AADR Annual Meeting is being held in conjunction with the 40th Annual Meeting of the Canadian Association for Dental Research.

21 Mar 2016

Periodontitis linked to greater rates of cognitive decline in Alzheimer's disease patients

A new study, jointly led by the University of Southampton and King's College London, has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer's Disease.

11 Mar 2016

Patients with chronic kidney disease and periodontitis have higher mortality rate

New findings from the University of Birmingham show that patients with chronic kidney disease patients and periodontitis (severe gum disease) have a higher mortality rate than those with chronic kidney disease alone.

18 Feb 2016

Study estimates prevalence of periodontitis at state and local levels across U.S. using SAE method

The International and American Associations for Dental Research have published an article titled "Predicting Periodontitis at State and Local Levels in the United States" in the OnlineFirst portion of the Journal of Dental Research. In it, authors P.I. Eke, X. Zhang, H. Lu, L. Wei, G. Thornton-Evans, K.J. Greenlund, J.B. Holt and J.B. Croft estimate the prevalence of periodontitis at state and local levels across the United States by using a novel, small area estimation (SAE) method.

5 Feb 2016

Incidence and severity emerging CVD risk factors may differ between genders

The incidence and severity of both traditional and emerging cardiovascular disease (CVD) risk factors as well as the response to treatment may differ between genders. In this narrative review, several emerging CVD risk factors (i.e. inflammatory and haemostatic markers, endothelial dysfunction, homocysteine, lipid disorders, microalbuminuria/proteinuria, coronary artery calcium score, arterial stiffness, periodontitis, inflammatory bowel syndrome, obstructive sleep apnea, impaired glucose metabolism, metabolic syndrome and non-alcoholic fatty liver disease) are discussed in the context of gender differences.

5 Feb 2016

Doctoral thesis explores issues related to dental Implants

Almost 8 percent of patients experience loss of at least one implant within ten years. Even more develop peri-implantitis. Patients with periodontitis run a greater risk of both implant loss and peri-implantitis. A doctoral thesis at Sahlgrenska Academy has explored the various issues.

5 Nov 2015

Saint Louis University receives NIH grant to investigate development of new drugs to treat bone diseases

David Griggs, Ph.D., director of biology at Saint Louis University's Center for World Health & Medicine, has received a $1 million R01 grant from the National Institutes of Health to investigate the development of what could be a new class of drugs to treat bone diseases.

30 Sep 2015

$Common Alzheimer's disease drug increases bone density, reduces fracture risks$

Common Alzheimer's disease drug increases bone density, reduces fracture risks

The most common drug used to treat Alzheimer's disease increases bone mass in mice, according to one of the first research articles published in the new open access journal Heliyon. The authors of the study, from Saitama Medical University in Japan, say this means the drug could also be used to treat bone loss diseases like osteoporosis and periodontitis, following further clinical research.

21 Sep 2015

Regular smokers at increased risk of tooth loss, new study confirms

A new study has confirmed that regular smokers have a significantly increased risk of tooth loss. Male smokers are up to 3.6 times more likely to lose their teeth than non-smokers, whereas female smokers were found to be 2.5 times more likely.

15 Sep 2015

Researchers link molecular dots between periodontitis and heart disease

Periodontitis is a risk factor for heart disease. Now a team of researchers has shown that a periodontal pathogen causes changes in gene expression that boost inflammation and atherosclerosis in aortic smooth muscle cells. The research is published ahead of print in Infection and Immunity, a journal of the American Society for Microbiology.

14 Sep 2015

Research: Some immune cells convert into cells that trigger disease

Researchers at Case Western Reserve University School of Dental Medicine have unraveled one of the mysteries of how a small group of immune cells work: That some inflammation-fighting immune cells may actually convert into cells that trigger disease.

22 May 2015

Natural substance could help people avoid cavities, gum disease

Arginine, a common amino acid found naturally in foods, breaks down dental plaque, which could help millions of people avoid cavities and gum disease, researchers at the University of Michigan and Newcastle University have discovered.

8 May 2015

Study shows that periodontal treatment can reduce symptoms of prostatitis

Treating gum disease reduced symptoms of prostate inflammation, called prostatitis, report researchers from Case Western Reserve University School of Dental Medicine and the Departments of Urology and Pathology at University Hospitals Case Medical Center.

6 May 2015