Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that cigarette smoking boosts the risk of peripheral artery disease, and this elevated risk can persist up to 30 years after smoking cessation.
Microvascular disease is independently associated with a higher risk of leg amputation compared to people without the disease, according to new research in the American Heart Association's journal Circulation.
For people who survive a heart attack, the days immediately following the event are critical for their longevity and long-term healing of the heart's tissue.
Millions of patients do not benefit from taking statins and fail to achieve a cholesterol level low enough to reduce their risk of heart or stroke, report researchers.
New research published in the March 18th edition of Lipids showed that people who have peripheral artery disease have a lower Omega-3 Index compared to those who don't have the disease.
Researchers at the University of Virginia School of Medicine have discovered an ingredient vital for proper blood vessel formation that explains why numerous promising treatments have failed.
A daily aspirin is a commonly used, generally safe therapy for people who need help preventing heart attacks or stroke.
African Americans who smoke cigarettes are more likely than those who don't smoke to develop peripheral artery disease, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.
For the first time, researchers have successfully cultivated “vascular organoids” in a petri dish that perfectly mimic real human blood vessels.
The cholesterol-lowering drugs called statins have demonstrated substantial benefits in reducing the risk of heart attacks and strokes caused by blood clots (ischemic strokes) in at-risk patients.
Cook Medical announced that a new 5 mm diameter version of Zilver® PTX® was approved by the FDA. It is the first 5 mm drug-eluting stent in the U.S. with lengths available up to 140 mm that is indicated to treat vessels as small as 4mm in diameter.
Resistant hypertension affects 12 percent to15 percent of patients treated for high blood pressure according to a new scientific statement from the American Heart Association.
Cristina Sabliov, LSU Biological and Agricultural Engineering professor, and Tammy Dugas, professor in the LSU School of Veterinary Medicine's Department of Comparative Biomedical Sciences, have joined forces to fight peripheral artery disease, or PAD, an ailment affecting 8 million Americans.
Bleeding in patients treated with anticoagulants should stimulate a search for cancer, according to late breaking results from the COMPASS trial presented today at ESC Congress 2018.
Combined oral anticoagulant and antiplatelet therapy is associated with a worse prognosis than anticoagulation alone in newly diagnosed atrial fibrillation patients without a clear indication for antiplatelets, according to late breaking results from the GARFIELD-AF registry presented today at ESC Congress 2018.
Patients with cardiovascular disease who develop major internal bleeding are much more likely to be diagnosed with cancer, a large international clinical trial has found.
A weight loss drug does not increase cardiovascular events, according to late breaking results from the CAMELLIA-TIMI 61 trial presented today in a Hot Line Session at ESC Congress and published in the New England Journal of Medicine.
A single pill with two drugs could transform blood pressure treatment, according to the 2018 European Society of Cardiology and European Society of Hypertension Guidelines on arterial hypertension published online today in European Heart Journal, and on the ESC website.
Treatments that restore blood flow to the lower limbs of people with a serious circulation condition may be cheaper and associated with longer survival, than amputation according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.
Higher levels of oxidative stress in males results in lower levels of cofactor BH needed to make the powerful blood vessel dilator nitric oxide.