Pertussis News and Research

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Discovery provides basis for new pertussis treatments

The worldwide spreading of the whooping cough, also known as pertussis, has substantially increased since 2010. Researchers from the Biozentrum, University of Basel, have investigated structure and function of an important membrane protein of the bacterium causing pertussis. They discovered that the protein structure differs from a previously postulated model.

24 Jun 2015

Genticel announces positive results of new multivalent HPV therapeutic vaccine based on Vaxiclase platform

Genticel, a French biotechnology company and developer of innovative immunotherapies to prevent cancers caused by the human papillomavirus (HPV), announces today positive preclinical in vivo proof of concept results of GTL002, its multivalent HPV therapeutic vaccine candidate based on the Company’s versatile Vaxiclase platform.

2 Jun 2015

Group Health Research Institute conducts first randomized trial to tackle vaccine hesitancy

Group Health Research Institute conducted the first randomized trial to test an intervention aimed at improving hesitancy about early childhood vaccines by working directly with doctors. Vax Northwest, a Washington state public-private partnership, developed the intervention.

2 Jun 2015

Preclinical data from Synthetic Biologics' SYN-005 for Pertussis treatment presented at ECCMID 2015

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, announced that preclinical data from its novel SYN-005 program for the treatment of Pertussis were presented in two posters at ECCMID 2015 (European Congress of Clinical Microbiology and Infectious Diseases), on April 25, 2015, in Copenhagen, Denmark.

27 Apr 2015

WHO: Progress towards global vaccination targets 'far off track'

Progress towards global vaccination targets for 2015 is far off track with 1 in 5 children still missing out on routine life-saving immunizations that could avert 1.5 million deaths each year from preventable diseases. In the lead-up to World Immunization Week 2015 (24 -30 April), the World Health Organization is calling for renewed efforts to get progress back on course.

24 Apr 2015

New text message alert system helps parents remember child's vaccination appointments

Nearly a third of all children nationwide and in Kentucky aren't up-to-date with the vaccination schedule recommended by the Centers for Disease Control (CDC), but not because their parents are refusing vaccines. Evidence suggests parents tend to forget appointments when children are scheduled to receive immunizations.

16 Apr 2015

Infectious diseases experts release new guidance to avoid infections during hospital visits

Leading infectious diseases experts have released new guidance for healthcare facilities looking to establish precautions for visitors of patients with infectious diseases. The guidance looks to reduce the potential for healthcare visitors in spreading dangerous bacteria within the healthcare facility and community.

13 Apr 2015

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio today revealed the molecular structure of the cytotoxin from Mycoplasma pneumoniae, a widespread, highly contagious bacterium that infects the lungs.

8 Apr 2015

FDA approves Quadracel vaccine to protect young children from life-threatening diseases

Sanofi Pasteur, the vaccines division of Sanofi, announced today that the U.S. Food and Drug Administration has approved use of Quadracel (Diphtheria and Tetanus Toxoids and Acellular Pertussis Absorbed and Inactivated Poliovirus; DTaP-IPV) vaccine for active immunization against diphtheria, tetanus, pertussis and poliomyelitis in children 4 through 6 years of age.

25 Mar 2015

WHO calls for intensification of routine immunization services in all Ebola-affected areas

A growing risk of outbreaks of measles, pertussis, and other vaccine-preventable diseases in countries affected by Ebola must be countered by urgent scaling up of routine immunization activities, according to the World Health Organization.

21 Mar 2015

Ebola crisis increases susceptibility to measles, other vaccine-preventable illnesses

Johns Hopkins Bloomberg School of Public Health researchers say that major disruptions in the health care systems in West Africa caused by the Ebola crisis have led to significant decreases in vaccinations for childhood diseases, increasing susceptibility to measles and other vaccine-preventable illnesses.

13 Mar 2015

Serum Institute of India to use Genticel's Vaxiclase platform to develop pertussis vaccines

Genticel, a French biotechnology company and leading developer of therapeutic vaccines, today announces that it has licensed its Vaxiclase technology to Serum Institute of India Ltd., for use as a component in acellular multivalent combination vaccines including pertussis antigens.

3 Feb 2015

Effective vaccine booster schedules needed to fight against whooping cough resurgence

A key to victory in battle, according to Chinese general and military strategist Sun Tzu, is to know your enemy. In the current fight against whooping cough resurgence, perhaps the biggest obstacle is an incomplete understanding of its underlying causes, according to a University of Michigan population ecologist.

20 Jan 2015

Researchers identify clusters of underimmunization, vaccine refusal in Northern California

Researchers used spatial analysis software and electronic medical records to identify clusters of underimmunization and vaccine refusal among Kaiser Permanente members in Northern California, according to a study published today in the journal Pediatrics.

19 Jan 2015

Tdap vaccination during pregnancy not associated with increased risk of preterm delivery

Among approximately 26,000 women, receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during pregnancy was not associated with increased risk of preterm delivery or small-for-gestational-age birth or with hypertensive disorders of pregnancy, although a small increased risk of being diagnosed with chorioamnionitis (an inflammation of the membranes that surround the fetus) was observed, according to a study in the November 12 issue of JAMA.

12 Nov 2014

MinuteClinic enters into clinical collaboration agreement with Lifespan

MinuteClinic, the retail medical clinic of CVS Health, and Lifespan, Rhode Island's largest health system, which includes five partner hospitals and multiple physician groups, announced today that they have entered into a clinical collaboration agreement.

27 Oct 2014

Foreign-born residents with low vaccination rates face greater risk of exposure to diseases

Foreign-born residents with low vaccination rates and their relatives in the U.S. are at greater risk of exposure to several vaccine-preventable diseases, e.g. influenza; pneumococcal diseases; tetanus, diphtheria and pertussis; hepatitis A; hepatitis B; shingles; and HPV, the human papilloma virus, which can lead to some types of cancer.

16 Oct 2014

Viewpoints: New insurers suggest health law success; slow response on Ebola

Before Obamacare launched, conservative outlets warned that the law would collapse as insurers shunned the overpriced, overregulated insurance exchanges.

26 Sep 2014

Sustained international efforts can help reduce premature deaths by 40% over next 20 years

New research published today [Friday 19 September] in The Lancet suggests that, with sustained international efforts, the number of premature deaths could be reduced by 40% over the next two decades (2010-2030), halving under–50 mortality and preventing a third of the deaths at ages 50–69 years.

19 Sep 2014

Synthetic Biologics' SYN-005 antibody gets FDA Orphan Drug designation for Pertussis treatment

Synthetic Biologics, Inc., a biotechnology company developing novel anti-infective biologic and drug programs targeting specific pathogens that cause serious infections and diseases, announced today that the U.S. Food and Drug Administration has granted Orphan Drug designation to the Company's proprietary SYN-005 monoclonal antibody (mAb) combination for the treatment of Pertussis, more commonly known as whooping cough.

15 Sep 2014