Petri Dish News and Research

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Pannexin1 protein may play an important role in mechanics of tumors

By studying tumor cell behavior in a novel "scaffold-free" 3-D system, researchers have determined that the protein Pannexin1 may play an important biomechanical role in binding tissues together, an effect that is lost in cancerous cells.

31 Jan 2012

Inhibiting glutaminase can curb growth of B cell cancers

Cancer cells have been long known to have a "sweet tooth," using vast amounts of glucose for energy and for building blocks for cell replication.

11 Jan 2012

Cancer cells feed on sugar-free diet

Cancer cells have been long known to have a “sweet tooth,” using vast amounts of glucose for energy and for building blocks for cell replication.

10 Jan 2012

Stem cell like progenitor cells could be key to aging slowly: Study

In new research on mice, scientists have found that stem cells could help slow the aging process. This new research was conducted on mice that had been bred to have progeria, a disorder that causes premature aging. Mice with the condition typically live only 21 to 28 days instead of the usual two years.

4 Jan 2012

Rainbow Biosciences signs letter of intent to form new joint venture with n3D

Rainbow Biosciences, a division of Rainbow Coral Corp. announced today that it signed a letter of intent to acquire or form a new joint venture with cutting-edge biotech firm n3D Biosciences, Inc.

12 Dec 2011

Implantable replacement cartilages hold promise for damaged knees, shoulders, ears and noses

A lab discovery is a step toward implantable replacement cartilage, holding promise for knees, shoulders, ears and noses damaged by osteoarthritis, sports injuries and accidents.

3 Dec 2011

Most people with Timothy syndrome mutation have autistic symptoms

Neuroscientists at Stanford University School of Medicine have homed in on potential differences in autistic people's brain cells by studying brainlike spheres grown in an elaborate process from skin cells.

28 Nov 2011

Research shows how the bite of a small Texas snake causes extreme pain

Examining venom from a variety of poisonous snakes, a group of researchers at the University of California, San Francisco has discovered why the bite of one small black, yellow and red serpent called the Texas coral snake can be so painful.

17 Nov 2011

Cultivating cells in sealed, sterile plastic bags

Using plasmas, sealed plastic bags can be modified at atmospheric pressure so that human cells can adhere to and reproduce on their walls. Cell culture bags of this kind are an important aid for research and clinical purposes and may eventually replace the Petri dishes used today.

11 Nov 2011

ESCs express genes linked with early germ cell specification

Ordinarily, embryonic stem cells exist only a day or two as they begin the formation of the embryo itself. Then they are gone. In the laboratory dish, however, they act more like perpetual stem cells - renewing themselves and exhibiting the ability to form cells of almost any type, a status called totipotency.

14 Oct 2011

Scientists reprogram skin cells of patients with mental disorders into brain cells

For many poorly understood mental disorders, such as schizophrenia or autism, scientists have wished they could uncover what goes wrong inside the brain before damage ensues.

13 Oct 2011

Scientists find a way to rapidly produce pure populations of oligodendrocyte progenitor cells

Scientists at Case Western Reserve University School of Medicine found a way to rapidly produce pure populations of cells that grow into the protective myelin coating on nerves in mice. Their process opens a door to research and potential treatments for multiple sclerosis, cerebral palsy and other demyelinating diseases afflicting millions of people worldwide.

26 Sep 2011

Researchers inject cultured red blood cells created from HSCs into human donor

For the first time, researchers have successfully injected cultured red blood cells (cRBCs) created from human hematopoietic stem cells (HSCs) into a human donor, according to study results published today in Blood, the Journal of the American Society of Hematology.

3 Sep 2011

New medicines to target LPA receptors may prevent serious developmental brain diseases

Examining brain damage that occurs when fetuses in the womb are deprived of oxygen, researchers at The Scripps Research Institute have discovered that damage does not occur randomly but is linked to the specific action of a naturally occurring fatty molecule called LPA, acting through a receptor that transfers information into young brain cells.

2 Sep 2011

VOA News examines new drug compound that shows broad-based efficacy in lab tests

VOA News looks at a new drug compound developed by researchers at the Massachusetts Institute of Technology (MIT) that they say has so far "killed every virus it's been tested on in the laboratory." "The drug - known by the acronym DRACO - works by chemically targeting viral-infected cells and prompting them to self-destruct, eliminating the disease in the process," VOA writes.

20 Aug 2011

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue.

18 Aug 2011

Scientists study how nervous system translates sensory information into coordinated motor output

Escape responses are some of the most studied behaviors by neurobiologists who want to understand how the brain processes sensory information. The ability to evade predators plays a vital role in the process of natural selection.

30 Jul 2011

New insights into sleep difficulties among older people

A new study of the brain's master circadian clock - known as the suprachiasmatic nucleus, or SCN - reveals that a key pattern of rhythmic neural activity begins to decline by middle age. The study, whose senior author is UCLA Chancellor Gene Block, may have implications for the large number of older people who have difficulty sleeping and adjusting to time changes.

20 Jul 2011

A*Star Institute of Microelectronics shortens drug development cycle with new silicon-based screening tool

Researchers from A*STAR Institute of Microelectronics (IME) have developed a lateral silicon-based drug screening tool that has demonstrated simultaneous capture of 12 individual cells – 12 times higher throughput than conventional patch clamping. The device can be scaled up to allow 1536 cell-recordings simultaneously, permitting 16 times higher throughput than existing planar patch clamp approach.

19 Jul 2011

Researchers identify potential therapeutic target for ER-negative breast cancer

Using a new in vivo screening system, Whitehead Institute researchers have identified a protein in the serine biosynthesis pathway that is essential in estrogen receptor (ER)-negative breast cancer—a notoriously difficult disease to treat associated with low five-year survival rates.