Phenylalanine News and Research

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Gene editing breakthrough could offer new hope for people with phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

2 Nov 2023

Moringa-infused gluten-free sourdough offers health boost for all, especially celiacs

Researchers have developed a gluten-free sourdough bread fortified with Moringa oleifera, an unconventional crop known for its health benefits. The study found that this novel bread formulation offers enhanced nutritional content, including higher levels of protein and essential minerals, making it a viable option for people with celiac disease and those seeking healthier bread alternatives.

30 Oct 2023

New insights into coronavirus E channel could lead to antiviral drugs

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19.

13 Oct 2023

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Diet sodas trick your saliva: Study reveals how sweetened drinks impact oral enzymes and insulin levels

The study investigates the effects of sweetened beverages on salivary insulin, aspartame, and alpha-amylase levels in healthy young adults. It found that diet soft drinks led to higher salivary aspartame and insulin levels compared to sweetened water, raising questions about artificial sweeteners' impact on metabolic processes.

5 Sep 2023

Study characterizes SARS-CoV-2 subvariants to inform development of next-generation COVID-19 vaccines

Researchers characterized two novel SARS-CoV-2 XBB variants, EG.5.1 and XBB.2.3.

4 Sep 2023

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

Researchers investigated the differential impact of HIV/tuberculosis co-infection on lipid and metabolic profiles.

23 Aug 2023

The interplay between immunity, the nervous system, and microbiota

Researchers review the influence of the gut microbiota on neural and immune network

15 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

Penn Medicine and CHOP receive $26 million NIH grant to develop treatments for three rare genetic diseases

A Penn Medicine and Children's Hospital of Philadelphia (CHOP) team will seek to develop treatments for three rare, incurable genetic diseases with the help of a $26 million grant from the National Institutes of Health (NIH).

1 Aug 2023

The role of diet in the management of retinal vein occlusion

Researchers investigate the potential impact of dietary habits on retinal vein occlusion.

27 Jul 2023

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.

21 Jul 2023

Aspartame intake and cancer risk: What you need to know

Aspartame is a low-calorie sweetener that is approximately 200 times sweeter than sugar and is used to replace sugar and provide sweetness in energy-reduced food, or food with no added sugars.

14 Jul 2023

WHO to declare artificial sweetener aspartame as possible carcinogen

The World Health Organization recently indicated that aspartame will likely be declared a “possible carcinogen to humans.”

29 Jun 2023

The Lancet study unveils exciting findings on retatrutide as a novel treatment for type 2 diabetes

Researchers performed a phase II randomized clinical trial (RCT).

29 Jun 2023

Elucidating the role of the gut-brain-axis in autism

The study investigates the relationship between the gut and the brain in autism spectrum disorder (ASD), identifying microbial profiles and metabolic products associated with ASD phenotypes, dietary patterns, and inflammation. The findings provide insights into the role of the gut-brain axis in ASD and its potential impact on understanding and managing the disorder.

28 Jun 2023

Mapping the by-products of bacteria processing amino acids associated with cardiovascular disease

A Cleveland Clinic research team recently published an "atlas" of metabolites associated with cardiovascular disease in the European Heart Journal. The novel findings provide key details about the routes and potential branching paths taken by bacteria and metabolic by-products, metabolites.

23 Jun 2023