Phosphorylation News and Research

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Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Researchers developed a screening platform and identified molecules with anti-CoV activity.

12 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Study reveals a promising therapeutic target for Alzheimer's disease

In a recent search for gene variants associated with Alzheimer's disease (AD), several affected families showed a mutation in an enzyme called protein kinase C-alpha (PKCα). Family members with this mutation had AD; those without the mutation did not.

28 Nov 2022

New chemical probe can selectively inhibit human COQ8A protein in cells

Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone.

28 Nov 2022

Flavonoids with potential to fight allergies and inflammation

In a recent study published in the Biomedicine & Pharmacotherapy journal, researchers explored the anti-allergic and anti-inflammatory properties of flavonoids.

28 Nov 2022

Study provides a key link between the social environment and healthy brains

As people age, maintaining a positive and predictable social environment becomes more and more important. For instance, keeping close ties with friends and family has been identified as one of the key ingredients to healthy aging.

24 Nov 2022

Single drug compound may offer a promising new strategy for treating prostate cancer patients

A single drug compound simultaneously attacks hard-to-treat prostate cancer on several fronts, according to a new study in mice and human cells.

23 Nov 2022

Utilizing marine sources to extract DHA to treat Alzheimer’s

The anti-neurodegenerative effects of docosahexaenoic acid (DHA) and DHA-rich phospholipids (DH-PL) derived from fisheries and aquaculture byproducts.

15 Nov 2022

Melatonin could be a potential therapy for long-COVID symptoms

A recent review published in the journal Biomolecules discussed the potential uses of melatonin in treating brain fog, and chronic fatigue syndrome or myalgic encephalomyelitis symptoms associated with long coronavirus disease (COVID)

9 Nov 2022

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

In a recent study posted to the Research Square* preprint server and under review at the Nature Portfolio journal, researchers reported activation and maturation of antigen-presenting cells (APCs) by lipid nanoparticles (LNPs).

9 Nov 2022

New biomarker could aid in early diagnosis of Alzheimer’s disease

A definitive diagnosis of Alzheimer's disease (AD) was once only possible after someone had died, but recent biomarker studies have led to the development of imaging and spinal fluid tests for those still living.

9 Nov 2022

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Researchers identified a genetic association signal, via genome-wide association studies, between severe COVID-19 with systemic lupus erythematosus, an autoimmune disease.

7 Nov 2022

Phosphorylation News and Research

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Detection of filoviruses by the innate immune system

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Study reveals a promising therapeutic target for Alzheimer's disease

New chemical probe can selectively inhibit human COQ8A protein in cells

Flavonoids with potential to fight allergies and inflammation

Study provides a key link between the social environment and healthy brains

Single drug compound may offer a promising new strategy for treating prostate cancer patients

Utilizing marine sources to extract DHA to treat Alzheimer’s

Melatonin could be a potential therapy for long-COVID symptoms

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

New biomarker could aid in early diagnosis of Alzheimer’s disease

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Researchers discover molecular mechanisms behind mitochondrial dysfunction in chronic heart failure

Licorice root extract shows potential as a COVID-19 treatment

Salk's three collaborative projects win 2022 Curebound Discovery Grant

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

Researchers identify a previously unknown mitochondrial disease in identical twins

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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