Photodynamic Therapy News and Research

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Combined therapeutic approach of stenting and photodynamic therapy improves survival in late stage liver cancer patients

A combined therapeutic approach of stenting and photodynamic therapy may improve survival rates for patients suffering from advanced liver bile duct cancer, according to a study published this month in Clinical Gastroenterology and Hepatology , the official journal of the American Gastroenterological Association (AGA) Institute.

12 Mar 2008

Light powered platinum more targeted and powerful than similar cancer treatments

Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light activation" to kill cancer cells in much more targeted way than similar treatments.

28 Dec 2007

Tumour cells could be used to develop personalised light-activated cancer vaccines

Cancer tissue taken directly from patients could be used to produce a light-triggered vaccine to target and treat their own tumours, according to a study published in the British Journal of Cancer.

14 Nov 2007

New approaches to wet age-related macular degeneration treatment

Two particularly notable research presentations at the American Academy of Ophthalmology's Annual Meeting described new approaches to the treatment of "wet" Age-Related Macular Degeneration (AMD), the most common cause of severe vision loss in the western world in people over age 50.

13 Nov 2007

New way to deliver agents for the treatment of skin cancer

Queen's University scientists have hit upon a revolutionary way to deliver agents for the treatment of skin cancer.

1 Oct 2007

Organically modified silica nanoparticles with covalently incorporated photosensitizer for photodynamic therapy of cancer

Photodynamic therapy, in which light activates a chemical known as a photosensitizer, triggering the production of cell-killing reactive oxygen, has proven itself as an effective therapy for a limited number of cancers.

27 Sep 2007

Jet injection system to improve skin cancer treatment

Researchers at Queen's University in Belfast have demonstrated that needle-free jet injection of an agent used in the treatment of skin cancer significantly increases the amount delivered into skin, compared to the conventional approach of topical application.

10 Sep 2007

Concentrated radio waves proide new approach to treating precancerous esophagus condition

The use of concentrated radio waves appears to be a safe and effective way to "burn" away abnormal cell growth in the esophagus that can be a precursor of cancer.

24 May 2007

Capsule endoscopy effective in diagnosing gastrointestinal bleeding and small bowel Crohn's disease in children

The technology has been used successfully at Thomas Jefferson University Hospital for more than five years to diagnose unexplained abdominal bleeding in adults.

22 May 2007

Cancer cells can be killed by a new cancer drug that is triggered by a laser light

Their paper describes how these new photosensitizer drugs can only be activated by light once they have been localized in the target tumour cells. For the first time Zheng and Wilson have demonstrated that tumour cells can be selectively attacked using a PDT.

17 May 2007

Drug delivery system that consists of nanocrystals of a hydrophobic drug

The problem of efficiently delivering drugs, especially those that are hydrophobic or water-repellant, to tumors or other disease sites has long challenged scientists to develop innovative delivery systems that keep these drugs intact until reaching their targets.

8 Mar 2007

Nanoparticles advance photodynamic therapy to kill tumor cells

Photodynamic therapy (PDT) is a powerful approach for destroying tumors, one that uses light and a light-sensitive chemical to rapidly kill cells.

20 Feb 2007

Vascular targeted nanoparticles for imaging and treatment of brain tumors

Combining two promising approaches to diagnosing and treating cancer, a multidisciplinary research team at the University of Michigan has created a targeted multifunctional polymer nanoparticle that successfully images and kills brain tumors in laboratory animals.

4 Dec 2006