Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

UCI researchers develop noninvasive, at-home saliva test to detect COVID-19

Researchers in the Henry Samueli School of Engineering at the University of California, Irvine announced promising results in the development of a noninvasive at-home antigen test to detect the spike of SARS-CoV-2 proteins in saliva.

9 Dec 2020

People with Bartonella infection exhibit neuropsychiatric symptoms, skin lesions

Bartonella bacteria are increasingly recognized as an emerging infectious disease threat. A new study by North Carolina State University researchers has found additional instances of Bartonella infection in humans who exhibited neuropsychiatric symptoms, a subset of whom also had skin lesions.

8 Dec 2020

New 'nanoPCR' technology can accurately diagnose COVID-19 in less than 20 minutes

A "nanoPCR" technology was developed for the point-of-care (POC) diagnosis of coronavirus disease-19 (COVID-19).

8 Dec 2020

Saliva samples may be reliable alternative to nasal swabs for SARS-CoV-2 testing

A team of researchers from various institutes in Switzerland report how saliva samples may be a strong alternative to nasal swaps in PCR-related SARS-CoV-2 testing.

8 Dec 2020

Paper-based electrochemical sensor can enable rapid detection of SARS-CoV-2

As the COVID-19 pandemic continues to spread across the world, testing remains a key strategy for tracking and containing the virus.

7 Dec 2020

Sensitive testing system enables rapid, reliable detection of resistance in bacteria

Researchers from the University of Basel have developed a sensitive testing system that allows the rapid and reliable detection of resistance in bacteria.

7 Dec 2020

STE90-C11, a SARS-CoV-2 neutralizing antibody, shows high inhibition of RBD-ACE2 binding

In a new study, researchers describe the identification of a neutralizing antibody that binds to the RBD at the same site as the human host cell receptor.

7 Dec 2020

High-performance ELISA for serology in mild-moderate non-hospitalized COVID-19

A new study describes an ELISA assay that combines the detection of IgM, IgA, and IgG antibodies against the SARS−CoV−2 trimeric spike glycoprotein.

7 Dec 2020

COVID-19 single-shot segmentation for chest CT-based diagnosis

A new study from an artificial intelligence (AI) scientist describes a method to predict COVID-19 from a single chest CT shot.

4 Dec 2020

High seroprevalence of short-lived anti-SARS-CoV-2 antibodies in Paris

A recent study indicates a high seroprevalence of antibodies against SARS-CoV-2 among individuals working in a Paris-based institute.

3 Dec 2020

Guidelines for accurate amplicon-based sequencing of SARS-CoV-2

A new study describes much-needed guidelines for reliable viral sequencing, validated in a large group of clinical samples.

3 Dec 2020

New lab-on-a-chip can process and present results rapidly

The chip, developed at Imperial College London and known as TriSilix, is a 'micro laboratory' which performs a miniature version of the polymerase chain reaction (PCR) on the spot. PCR is the gold-standard test for detecting viruses and bacteria in biological samples such as bodily fluids, faeces, or environmental samples.

2 Dec 2020

Researchers evaluate the most appropriate test for COVID-19

Until a vaccine is available, curbing the coronavirus pandemic relies heavily on how quickly a potentially exposed individual can be tested and quarantined.

2 Dec 2020

How COVID-19 highlights the uncertainty of medical testing

Dr. Jacqueline Chu considered the man with a negative coronavirus test on the other end of the phone, and knew, her heart dropping, that the test result was not enough to clear him for work.

1 Dec 2020

Chinese woman still sheds SARS-CoV-2 over four months post-infection

A new study by Chinese scientists explore an unusual case of extended viral shedding in a 68-year-old woman up to four months post-infection.

1 Dec 2020

Severe COVID-19 can produce high long-term neutralizing antibodies, study finds

A new study published by a team of scientists in Spain indicates that neutralizing immunity can last for up to 8 months, despite a steep drop in antibody titer over this time.

30 Nov 2020

Steam inhalation therapy found to inactivate SARS-CoV-2 virions

Researchers have published a study on the efficacy of steam inhalations as another possible treatment to help mitigate SARS-CoV-2 infection.

30 Nov 2020

Resveratrol shows potential as SARS-CoV-2 antiviral, study finds

A recent study reveals that resveratrol, a phenolic compound produced by spermatophytes, can inhibit the viral replication SARS-CoV-2.

27 Nov 2020

Monoclonal antibody HB27 shows potent neutralizing activity against SARS-CoV-2

A new study reports a very promising anti-SARS-CoV-2 monoclonal antibody, HB27, that appears to have two distinct mechanisms of action inhibiting the virus-host cell interaction and subsequent infection.

27 Nov 2020

$Multiple fractionation approach for measuring cancer biomarker enrichment in exosomes$

Multiple fractionation approach for measuring cancer biomarker enrichment in exosomes

Postnova Analytics reports that researchers from the University of Utah have used a novel combination of Asymmetrical Flow Field-Flow Fractionation and Centrifugal Field-Flow Fractionation to measure cancer biomarker enrichment in exosomes.

From Postnova Analytics 27 Nov 2020