Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Long-COVID associated with a greater likelihood of unemployment

In a recent study published in the journal JAMA Network Open, researchers assessed the unemployment rates among individuals who developed post–coronavirus disease 2019 (COVID-19) condition (PCC) or long COVID after an acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to determine the functional and neurocognitive impairment levels associated with long COVID.

16 Feb 2023

Chest CT findings and pulmonary function in COVID-19 patients

In a recent study published in the Radiology journal, researchers performed the longitudinal evaluation of chest computerized tomography (CT) findings along with pulmonary function in coronavirus disease 2019 (COVID-19) patients.

16 Feb 2023

After recovering from mild to moderate COVID-19, asthma control deteriorates

In a recent study published in the Respiratory Research journal, researchers in Hong Kong assessed the deterioration of asthma control in patients recovering from mild to moderate coronavirus disease 2019 (COVID-19).

16 Feb 2023

Nirmatrelvir–ritonavir found to lower COVID-19 severity outcomes

Researchers evaluated the effectiveness of nirmatrelvir–ritonavir in preventing coronavirus disease 2019 (COVID-19) severity outcomes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant predominance.

16 Feb 2023

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Researchers performed a retrospective population-wide cohort study using anonymized data in Hong Kong, China, between February 26 and July 3, 2022.

16 Feb 2023

Post-COVID-19 CT scans show lung abnormalities persist two years later

In a recent study published in the journal Radiology, researchers longitudinally assessed changes in chest computed tomography (CT) abnormities and lung function among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

New insights into the driving factors of COVID-19 dynamics in England

In a recent study posted to the medRxiv* preprint server, researchers provided quantitative estimates of population-level drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and infection severity by fitting coronavirus disease 2019 (COVID-19) epidemiological surveillance data from England into dynamic transmission models.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

"AutoPLP" technique enables rapid, accurate detection of mutating bacteria and viruses

As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment.

15 Feb 2023

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

Researchers investigated the tolerability and safety of a microbiome therapy called SER-109 to treat recurrent infections of Clostridioides difficile in adults.

15 Feb 2023

Fibromyalgia may occur post-COVID

Researchers investigate the incidence of fibromyalgia among individuals hospitalized due to SARS-CoV-2 infection.

14 Feb 2023

Influenza A virus suppresses SARS-CoV-2 replication during co-infection

SARS-CoV-2 does not suppress the replication of influenza A in simultaneous or sequential co-infections.

13 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

No new SARS-CoV-2 variants detected in China since COVID policy change

In a recent study published in The Lancet, researchers reported the trends in coronavirus disease 2019 (COVID-19) cases and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in Beijing in 2022.

9 Feb 2023

Study suggests SARS-CoV-2 is likely to only infect placental mammals

Researchers perform ontological and taxonomical analysis of human coronavirus hosts.

9 Feb 2023

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Researchers describe a novel SARS-CoV-2 spike protein component vaccine called MT-001.

9 Feb 2023

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Researchers developed a WGS method that read four canonical DNA bases, viz., adenine (A), cytosine (C), guanine (G), and thymine (T) plus 5mC and 5hmC, epigenetic variants of unmodified C to yield an accurate six-letter digital readout in a single workflow.

9 Feb 2023