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Reducing air pollution associated with lower risk of all-cause dementia and Alzheimer's disease

Previous reports have linked long-term air pollution exposure with accumulation of Alzheimer's disease-related brain plaques, but this is the first accumulated evidence that reducing pollution, especially fine particulates in the air and pollutants from the burning of fuel, is associated with lower risk of all-cause dementia and Alzheimer's disease.

27 Oct 2023

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

A four-year, $3.4 million grant to investigate molecular mechanisms and therapeutic treatments for acute respiratory distress syndrome (ARDS) has been awarded to UTHealth Houston researchers by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

26 Oct 2023

Doubts abound about a new Alzheimer’s blood test

For the first time, people worried about their risk of Alzheimer's disease can go online, order a blood test, and receive results in the privacy of their homes.

26 Oct 2023

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies.

25 Oct 2023

Oxford Vaccine Group launches a pioneering study into human immunity

This study will test the responses of cells in lymph nodes before and after immunization with flu and COVID-19 vaccines and compare reactions in older and younger adults.

25 Oct 2023

New consortium to build on breakthroughs in malaria research to develop P. vivax vaccines

Plasmodium vivax is the most widespread human malaria-causing pathogen with 2.5 billion people living at risk in Africa, South America, Oceania, and Asia.

24 Oct 2023

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

While breast cancer survival continues to improve, thanks to advances in detection and treatment, when breast cancer recurs – or returns after initial treatment – it is incurable.

24 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Beijing Chaoyang Hospital have developed a new "pseudo cell" formulation based on self-healing microcapsule-loading exosomes to treat diverse vitreoretinal diseases.

24 Oct 2023

Can strawberries mitigate Alzheimer's risk? Recent study suggests a possibility

Whether strawberry supplementation mitigates the risk for late-life dementia.

23 Oct 2023

Scientists develop gene therapy approach for rare paralyzing disease

The 50 families stretch from the Netherlands and the United Kingdom to the United States and China. Each family has a child who is paralyzed from a mutation in a single gene named Contactin-Associated Protein 1 (Cntnap1).

20 Oct 2023

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

Johns Hopkins researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive.

20 Oct 2023

New method uses extracellular vesicles to enhance immunotherapy responses in glioblastoma

A team of researchers at The University of Texas MD Anderson Cancer Center has developed a new method for using extracellular vesicles to enhance responses to immunotherapy in glioblastoma, potentially opening the door for wider use of engineered messenger RNA (mRNA) for cancer therapy.

19 Oct 2023

Study explores sex-specific effects in Alzheimers disease pathology

The role of biological sex in the development and progression of Alzheimer's Disease (AD).

19 Oct 2023

Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.

17 Oct 2023

Researchers receive NCI grant for the development of new pancreatic cancer therapies

Researchers at Washington University School of Medicine in St. Louis have received an NCI grant that will provide about $10.9 million to research programs for the development of new therapies for pancreatic ductal adenocarcinoma, the deadliest form of pancreatic cancer.

17 Oct 2023

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

The Foundation for Angelman Syndrome Therapeutics (FAST) announced today that the non-profit organization has entered into an exclusive global collaborative research and development agreement with the University of Pennsylvania to develop an investigational adeno-associated virus (AAV) gene therapy for Angelman syndrome (AS).

17 Oct 2023

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

The success and challenges of developing different tuberculosis (TB) vaccine types.

17 Oct 2023

Impact of ketogenic diets on breast cancer

The therapeutic potential of the ketogenic diet (KD) for breast cancer (BC).

17 Oct 2023

Preclinical News and Research

Reducing air pollution associated with lower risk of all-cause dementia and Alzheimer's disease

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

Doubts abound about a new Alzheimer’s blood test

How strep bacteria outsmart your immune system and why it matters for treatment

Oxford Vaccine Group launches a pioneering study into human immunity

New consortium to build on breakthroughs in malaria research to develop P. vivax vaccines

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Can strawberries mitigate Alzheimer's risk? Recent study suggests a possibility

Scientists develop gene therapy approach for rare paralyzing disease

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

New method uses extracellular vesicles to enhance immunotherapy responses in glioblastoma

Study explores sex-specific effects in Alzheimers disease pathology

Lung chip model offers new insights into how radiation damages the lungs

Researchers receive NCI grant for the development of new pancreatic cancer therapies

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

Impact of ketogenic diets on breast cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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