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New method uses extracellular vesicles to enhance immunotherapy responses in glioblastoma

A team of researchers at The University of Texas MD Anderson Cancer Center has developed a new method for using extracellular vesicles to enhance responses to immunotherapy in glioblastoma, potentially opening the door for wider use of engineered messenger RNA (mRNA) for cancer therapy.

19 Oct 2023

Study explores sex-specific effects in Alzheimers disease pathology

The role of biological sex in the development and progression of Alzheimer's Disease (AD).

19 Oct 2023

Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.

17 Oct 2023

Researchers receive NCI grant for the development of new pancreatic cancer therapies

Researchers at Washington University School of Medicine in St. Louis have received an NCI grant that will provide about $10.9 million to research programs for the development of new therapies for pancreatic ductal adenocarcinoma, the deadliest form of pancreatic cancer.

17 Oct 2023

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

The Foundation for Angelman Syndrome Therapeutics (FAST) announced today that the non-profit organization has entered into an exclusive global collaborative research and development agreement with the University of Pennsylvania to develop an investigational adeno-associated virus (AAV) gene therapy for Angelman syndrome (AS).

17 Oct 2023

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

The success and challenges of developing different tuberculosis (TB) vaccine types.

17 Oct 2023

Impact of ketogenic diets on breast cancer

The therapeutic potential of the ketogenic diet (KD) for breast cancer (BC).

17 Oct 2023

Fluorescence lifetime imaging shows promise for improved tumor detection

Removing a patient's tumor while sparing healthy tissue requires exquisite precision, but often surgeons must rely on their eyes and hands to determine where to cut.

16 Oct 2023

Insilico Medicine to present scientific data on novel anti-cancer assets at major cancer conferences

Clinical stage artificial intelligence (AI) drug discovery company Insilico Medicine ("Insilico") has been invited to present scientific data on its novel anti-cancer assets at three major upcoming cancer conferences -- the European Society for Medical Oncology (ESMO) conference in Madrid Oct. 20-24, 2023; the Society of Immunotherapy of Cancer (SITC) conference Nov. 1-5, 2023 in San Diego; and the San Antonio Breast Cancer Symposium (SABCS) Dec. 5-9, 2023.

16 Oct 2023

Researchers identify new biomarker to predict neuronal regeneration after injury

Neurons, the main cells that make up our brain and spinal cord, are among the slowest cells to regenerate after an injury, and many neurons fail to regenerate entirely.

16 Oct 2023

Antiverse and GlobalBio, Inc. extend collaboration to advance antibody cancer therapeutics

Antiverse Ltd (Antiverse) and GlobalBio, Inc. (GlobalBio) today announced they will be extending their collaboration to advance immune checkpoint inhibitors in cancer therapy.

From Antiverse 16 Oct 2023

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

Deep brain stimulation improves memory and promotes neuron growth in Rett mice

A recent study from the lab of Dr. Jianrong Tang, associate professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital shows that deep brain stimulation (DBS) of a specific brain region results in a significant and sustained improvement of memory in Rett mice.

13 Oct 2023

Nongenetic mechanisms play a role in lung cancer treatment resistance

In a recent study led by Ravi Salgia, M.D., Ph.D., the Arthur & Rosalie Kaplan Chair in Medical Oncology, a team of researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, and other institutions found that nongenetic mechanisms are important in lung cancer patients who develop a resistance to one cancer therapy.

13 Oct 2023

Stroke experts map out path for better patient outcomes

Scientists from The Florey are among the world's leading stroke experts who have mapped out how researchers and clinicians can improve outcomes for people who have survived a stroke.

12 Oct 2023

BioLizard launches new BioVerse Platform to accelerate life sciences R&D processes

BioLizard, the bioinformatics, data analytics and data management service and consulting company heading digital transformation in the life sciences industry, today announced the launch of its new BioVerse platform.

12 Oct 2023

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Researchers used a genetically engineered porcine donor to develop kidney grafts.

11 Oct 2023

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer's early stages, when it's easiest to treat.

10 Oct 2023

FDA approves the use of sound waves to break down tumors in humans for liver treatment

The U.S. Food and Drug Administration has approved the use of sound waves to break down tumors—a technique called histotripsy—in humans for liver treatment.

9 Oct 2023

Compound found to inhibit influenza virus replication by targeting host enzyme

How can the propagation of influenza viruses be stopped? For a new approach in the therapy of influenza infections, Prof. Hiroki Kato from the Institute of Cardiovascular Immunology at the University Hospital Bonn (UKB) and the Cluster of Excellence ImmunoSensation2 of the University of Bonn receives an Open Philanthropy grant of 2.2 million US dollars.

9 Oct 2023

Preclinical News and Research

New method uses extracellular vesicles to enhance immunotherapy responses in glioblastoma

Study explores sex-specific effects in Alzheimers disease pathology

Lung chip model offers new insights into how radiation damages the lungs

Researchers receive NCI grant for the development of new pancreatic cancer therapies

FAST joins with University of Pennsylvania to develop investigational AAV gene therapy for Angelman syndrome

Promising breakthroughs ignite hope for a novel and effective Tuberculosis vaccine

Impact of ketogenic diets on breast cancer

Fluorescence lifetime imaging shows promise for improved tumor detection

Insilico Medicine to present scientific data on novel anti-cancer assets at major cancer conferences

Researchers identify new biomarker to predict neuronal regeneration after injury

Antiverse and GlobalBio, Inc. extend collaboration to advance antibody cancer therapeutics

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

Deep brain stimulation improves memory and promotes neuron growth in Rett mice

Nongenetic mechanisms play a role in lung cancer treatment resistance

Stroke experts map out path for better patient outcomes

BioLizard launches new BioVerse Platform to accelerate life sciences R&D processes

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

New blood test could detect ovarian cancer early, improve treatment

FDA approves the use of sound waves to break down tumors in humans for liver treatment

Compound found to inhibit influenza virus replication by targeting host enzyme

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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