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Drug Discovery 2023: A Conversation with Professor Janet Hemingway

We spoke to Professor Janet Hemingway, founding Director of iiCON and Professor of Tropical Medicine at Liverpool School of Tropical Medicine.

9 Oct 2023

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers have delved into the intricate heterogeneity of glioblastoma, a notoriously aggressive brain tumor, using advanced single-cell RNA sequencing and innovative zebrafish avatars. Their findings spotlighted the LGALS1 gene's role in immunosuppression and suggested potential therapeutic avenues for personalized GBM treatment.

8 Oct 2023

Researchers develop innovative treatment option for therapy-resistant epilepsy

Neuroscientist Professor Sonja Bröer from Freie Universität Berlin is involved in the development of an innovative treatment option for therapy-resistant epilepsy.

6 Oct 2023

Pyrvinium can be repurposed as a preventative treatment for stomach cancer

A study published Oct. 4 in Gastroenterology further validates that pyrvinium, a drug that has been used for decades for intestinal pinworms, can be repurposed as a preventative treatment for stomach cancer.

6 Oct 2023

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs).

6 Oct 2023

Bio-Rad Extends Range of Anti-Idiotypic Antibodies for Use in Preclinical and Clinical Drug Development

Bio-Rad Laboratories, a global leader in life science research and clinical diagnostics products, today extended its range of recombinant monoclonal anti-idiotypic antibodies with the introduction of six antibodies specific to dupilumab (Dupixent) and the addition of new evolocumab (Repatha), ipilimumab (Yervoy), and secukinumab (Cosentyx) antibodies.

From Bio-Rad Laboratories 6 Oct 2023

USC-led team develops vaccine to boost immune system against superbugs

What if a vaccine, given to patients just before or after arriving at the hospital, could protect them against lethal superbugs that lurk in healthcare settings?

5 Oct 2023

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alzheimer's disease.

5 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Remote ischemic conditioning for acute stroke

The effect of remote ischemic conditioning (RIC) on functional outcomes in patients with acute stroke.

5 Oct 2023

Groundbreaking research focuses on brain health monitoring, early detection of neurodegenerative diseases

Associate Professor at the University of Oulu Teemu Myllylä, a leading expert in biomedical engineering, recently discussed his team's groundbreaking work in brain health monitoring and early detection of neurodegenerative diseases at the recent 6G-enabled sustainable society event.

4 Oct 2023

New nasal vaccine shows promise in preventing deadly Strep A infections

As Streptococcus A cases continue to be prevalent in Queensland and internationally, a new nasal vaccine could provide long-term protection from the deadly bacteria.

4 Oct 2023

Selective removal of aging cells represents a new paradigm for treating age-related diseases

A research team, led by Professor Ja Hyoung Ryu from the Department of Chemistry at UNIST, in collaboration with Professor Hyewon Chung from Konkuk University, has achieved a significant breakthrough in the treatment of age-related diseases.

4 Oct 2023

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a PhD student in the Institute of Chemical Biology EPSRC Centre for Doctoral Training (CDT) in Chemical Biology, at Imperial College London.

From Ubiquigent Limited 4 Oct 2023

Walking and Mediterranean diet may be the ticket to reducing dementia risk

The study explores the MedWalk intervention, promoting a Mediterranean-style diet and regular walking, to potentially slow cognitive decline in older adults without existing impairments. Despite COVID-19 disruptions, progress with 157 participants suggests this approach, rooted in psychosocial techniques, could offer a lifestyle-based deterrent against dementia and cognitive deterioration.

4 Oct 2023

Metabolism-targeting drug could offer new hope for cancer-related fatigue

Cancer-related fatigue (CRF) is a debilitating yet all-too-common condition, which can severely affect quality of life for patients undergoing treatment.

3 Oct 2023

Research opens the door for better use of people's own immune system T cells to fight cancer

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

3 Oct 2023

Optibrium releases powerful metabolism prediction capability in next generation StarDrop software

Optibrium, a leading developer of software and AI solutions for drug discovery, today launched the latest version of its drug discovery platform, StarDrop.

From Optibrium Ltd. 2 Oct 2023

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer's disease in its earliest stages, according to research published in the September issue of The Journal of Nuclear Medicine.

29 Sep 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

Preclinical News and Research

Drug Discovery 2023: A Conversation with Professor Janet Hemingway

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers develop innovative treatment option for therapy-resistant epilepsy

Pyrvinium can be repurposed as a preventative treatment for stomach cancer

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Bio-Rad Extends Range of Anti-Idiotypic Antibodies for Use in Preclinical and Clinical Drug Development

USC-led team develops vaccine to boost immune system against superbugs

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

Researchers spearhead a new method to hone in on new cancer drug targets

Remote ischemic conditioning for acute stroke

Groundbreaking research focuses on brain health monitoring, early detection of neurodegenerative diseases

New nasal vaccine shows promise in preventing deadly Strep A infections

Selective removal of aging cells represents a new paradigm for treating age-related diseases

Ubiquigent collaborates with Imperial College London on DUB probe discovery to facilitate preclinical and clinical target engagement studies

Walking and Mediterranean diet may be the ticket to reducing dementia risk

Metabolism-targeting drug could offer new hope for cancer-related fatigue

Research opens the door for better use of people's own immune system T cells to fight cancer

Optibrium releases powerful metabolism prediction capability in next generation StarDrop software

New tau PET radiotracer shows promise for early detection of Alzheimer's disease

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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